Results 141 to 150 of about 261,993 (301)
Bidirectional Soft Catalysts for Improved Power Performance of Li‐S Batteries
Advanced Science, EarlyView.A soft polymer‐metal catalyst is integrated into the binder to create a catalytically active microenvironment that accelerates bidirectional sulfur redox kinetics in lithium‐sulfur batteries. A model polyvinyl alcohol‐Cu catalyst enables high areal capacities at demanding current densities and stable cycling in pouch‐cell prototypes at 0.5 C, achieving
Maleesha M. Nishshanke +7 more
wiley +1 more source
Advanced Science, EarlyView.Amphiphilic sulfonated chitosan nanoparticles buffer endo/lysosomal acidity in microglia by limiting V‐ATPase membrane recruitment and restoring endosomal homeostasis. Following systemic administration, they accumulate in the ischemic hemisphere partly through association with infiltrating immune cells, suppress TLR3/IRF3 and TLR4/NF‐κB signaling ...
Xuanlin Wang +4 more
wiley +1 more source
Advanced Science, EarlyView.Integrative multi‐cohort analyses identify 14‐3‐3γ as a biomarker and regulator of cognitive vulnerability. Experimental studies show that 14‐3‐3γ loss is associated with Tau Thr205 phosphorylation, synaptic dysfunction, and cognitive impairment, while genetic overexpression or pharmacological stabilization of 14‐3‐3γ confers protective effects in ...
Shouqiang Zhu +5 more
wiley +1 more source
Density of polyribosomes in dendritic spines.
, 2013 Conditioning increases the density of polyribosomes located in spines and associated with excitatory (ANOVA ...
Elzbieta Pyza (283467) +5 more
core +1 more source
Advanced Science, EarlyView.Compared to E8, mTeSR1 culture downregulated WNT and TGF‑β signaling, and upregulated neural differentiation pathways, enhancing neural priming. Under skin organoid induction conditions, mTeSR1‑cultured hESCs generated organoids with significantly higher neuroepithelial differentiation.
Zhongliang Chen +7 more
wiley +1 more source
Advanced Science, EarlyView.MethyAnno enables robust and interpretable annotation of single‐cell DNA methylation data by integrating multi‐scale epigenetic information, bidirectional cross‐attention, and prototype‐based metric learning. The framework resolves rare and novel cell types across datasets while revealing cell‐type‐specific epigenetic signatures associated with disease
Yuhang Jia +4 more
wiley +1 more source
Information Processing in Dendritic Spines
, 1983 Dendritic spines are small twigs on the dendrites of a very large class of neurons in the central nervous system. There are between 10 (3) and 10 (5) spines per neuron, each one including at least one synapse, i.e.
Koch, C., Poggio, Tomaso A
core
Advanced Science, EarlyView.In the post‐stroke brain, Foxa2 induces the transcriptional upregulation of Nrsn1 in NSCs. Nrsn1 functionally couples with Smarcc1, modulating its nuclear availability and protein abundance, thereby influencing Smarcc1‐associated regulatory programs linked to neuronal lineage commitment. Through this coupling, Nrsn1 promotes the differentiation of NSCs
Ruolin Zhang +18 more
wiley +1 more source
Morphological Study of Dendritic Spines [PDF]
, 2011 Reconstruction of the neuron structure and the characterisation of dendritic spines is nowadays a hot topic in neurobiology research. Dendrites are cellular structures whose main objective is to conduct the electrochemical stimulation received from other
Baguear, Miguel Federico
core
Dendritic spines in Tc1 and Ts1Rhr mouse cortex.
, 2013 GFP electroporated embryos at E15 were allowed to develop normally until P21 or 3 months of age. A. Representative image of a wildtype (Ts1Rhr) dendrite segment, at P21. Arrows indicate thin spines. B. Dendritic spines in Ts1Rhr cortex at P21.
Elizabeth M. C. Fisher (245444) +7 more
core +1 more source