Results 211 to 220 of about 553,059 (371)

Copper and Iron‐Based Metal‐Organic Frameworks for Synergistic Cancer Phototherapies: Recent Advances, Challenges, and Future Prospects

Advanced Therapeutics, EarlyView.
The graphical abstract illustrates the combined effect of PTT and PDT using metal‐organic frameworks (MOFs) in a cancer treatment model. Tumor‐bearing mice are irradiated with different laser lights, which activate the MOF nanoparticles within cancer cells. The MOFs produce reactive oxygen species through PDT, while PTT elevates the temperature to kill
Kayalvizhi Samuvel Muthiah, Kalaiarasu Lakshminarayanan, Yu Chien Lin, Udesh Dhawan, Loganathan Rangasamy, Ren‐Jei Chung   +5 more
wiley   +1 more source

Dendritic Spine Structural Anomalies in Fragile-X Mental Retardation Syndrome

, 2000
Scott A. Irwin
openalex   +1 more source

Inositol 1,4,5-Trisphosphate 3-Kinase A Associates with F-actin and Dendritic Spines via Its N Terminus [PDF]

, 2001
Michael J. Schell, Christophé Erneux, Robin F. Irvine   +2 more
openalex   +1 more source

Rewiring Neuroimmunity: Nanoplatform Innovations for CNS Disease Therapy

Advanced Therapeutics, EarlyView.
This review explores emerging nanoplatform strategies designed to modulate neuroimmune responses for treating central nervous system (CNS) disorders. It examines structural and microenvironmental barriers, advances in multifunctional and targeted nanotechnologies, and highlights clinical progress and translational challenges, offering insights into the
Muhammad Usman Akbar, Weiwei Guo, Xin Shen, Yimeng Fang, Yilin Liu, Peng‐Yuan Wang, Roey Elnathan, Yaping Chen   +7 more
wiley   +1 more source

Dendritic spines provide cognitive resilience against Alzheimer's disease

Annals of Neurology, 2017
Benjamin D. Boros, Kelsey M. Greathouse, Erik G. Gentry, Kendall Curtis, Elizabeth L. Birchall, M. Gearing, Jeremy H. Herskowitz   +6 more
semanticscholar   +1 more source

EphB/Syndecan-2 Signaling in Dendritic Spine Morphogenesis [PDF]

, 2001
Iryna M. Ethell, Fumitoshi Irie, Matthew S. Kalo, John Couchman, Elena B. Pasquale, Yu Yamaguchi   +5 more
openalex   +1 more source

Enhancing the Effectiveness of Chemotherapy in Osteosarcoma by Targeting Tumour‐Associated Macrophages (TAMs) through STING Activation

Advanced Therapeutics, EarlyView.
Osteosarcoma isa highly aggressive bone cancer with an immunosuppressive tumor microenvironment that limits immunotherapy. This study explores STING pathway activation to reprogram tumor‐associated macrophages into a tumoricidal M1‐like phenotype and enhance doxorubicin efficacy. Results show that doxorubicin alone failed to activate the STING pathway,
Jordan C. O'Donoghue, Amanda Guitián‐Caamaño, Maeve Boyce, Fiona E. Freeman   +3 more
wiley   +1 more source

Structural and functional plasticity of dendritic spines – root or result of behavior?

Genes, Brain and Behavior, 2017
Cassandra D. Gipson, M. Olive
semanticscholar   +1 more source

SMYD3 Promotes Immune Evasion in Clear Cell Renal Cell Carcinoma via SREBP1‐Mediated Transactivation of CD47

Advanced Science, EarlyView.
Cancer cell‐intrinsic SMYD3 orchestrates an immunosuppressive microenvironment and impairs the response to PD‐1 blockade by reprogramming immune cells landscape in the tumor microenvironment of clear cell renal cell carcinoma (ccRCC). The immunomodulatory function of SMYD3 is mediated via the SREBP1/CD47 pathway.
Zhengfang Liu, Xiumei Zhao, Maolin Zang, Huiyang Yuan, Xin Qin, Xiaofeng Li, Shuo Zhao, Ruirong Tan, Keqiang Yan, Li Liu, Yidong Fan, Ning Zhang, Benkang Shi, Bo Han, Shouzhen Chen   +14 more
wiley   +1 more source

Aberrant Rac1-cofilin signaling mediates defects in dendritic spines, synaptic function, and sensory perception in fragile X syndrome

Science Signaling, 2017
Alexander Pyronneau, Qionger He, Jee-Yeon Hwang, M. Porch, A. Contractor, R. Zukin   +5 more
semanticscholar   +1 more source