Results 261 to 270 of about 553,059 (371)

A Peripheral Mechanism of Depression: Disturbed Intestinal Epithelial Per2 Gene Expression Causes Depressive Behaviors in Mice with Circadian Rhythm Disruption via Gut Barrier Damage and Microbiota Dysbiosis

Advanced Science, EarlyView.
Circardian rhythm disorder (CRD) causes abnormal expression of intestinal Period 2 (Per2) gene, which compromising intestinal barrier integrity and altering the gut microenvironment. Microbiota dysbiosis and aberrant metabolites production drive central inflammation, impair neurogenesis, and promote functional deficits, ultimately facilitating the ...
Huiliang Zhang, Xuan Qin, Haiyue Song, Jieru Zhou, Hui Wei, Lun Zhang, Yi Liu, Zhuoqun Wang, Yiren Zhang, Yiwen Lai, Jiayu Yang, Wenting Hu, Zhongshan Chen, Ji Zeng, Yu Jin, Xiaochuan Wang, Rong Liu   +16 more
wiley   +1 more source

The extracellular matrix molecule Collagen XVIII/CLE-1 affects neuronal dendritic spines. [PDF]

MicroPubl Biol
Lemons L M, McKillop H, Genao N, Francis M M.   +3 more
europepmc   +1 more source

Neurofilament Levels in Dendritic Spines Associate with Synaptic Status. [PDF]

Cells, 2023
Gürth CM, do Rego Barros Fernandes Lima MA, Macarrón Palacios V, Cereceda Delgado AR, Hubrich J, D'Este E.   +5 more
europepmc   +1 more source

Multiple EphB receptor tyrosine kinases shape dendritic spines in the hippocampus [PDF]

, 2003
Mark Henkemeyer, Olga S. Itkis, Michelle Ngo, Peter W. Hickmott, Iryna M. Ethell   +4 more
openalex   +1 more source

Weak and Tunable Adhesion–Clutch Drives Rapid Cell Migration and Glioblastoma Invasion

Advanced Science, EarlyView.
This study proposes that adhesion–clutch can mediate both cell motility and immobilization depending on the force amplitude. Weak adhesion–clutch is well‐suited for cell migration, without forming strong adhesions that impede cell motility. It propels rapid dendritic cell migration controlled by extracellular chemicals, as well as pathologically ...
Kentarou Baba, Ami Fukushi‐Kumagai, Megumi Morisaki, Ryosuke Takeuchi, Zhize Xiao, Yoshikazu Nagashima, Mizuki Sakai, Yasuna Higashiguchi, Hiroko Katsuno‐Kambe, Asako Katsuma, Yoshihiro Ueda, Yuji Kamioka, Daisuke Kawauchi, Tatsuo Kinashi, Yonehiro Kanemura, Naoyuki Inagaki   +15 more
wiley   +1 more source

Dendritic Spines of Layer 5 Pyramidal Neurons of the Aging Somatosensory Cortex Exhibit Reduced Volumetric Remodeling. [PDF]

J Neurosci
Ducote AL, Voglewede RL, Mostany R.
europepmc   +1 more source

Cocaine-induced proliferation of dendritic spines in nucleus accumbens is dependent on the activity of cyclin-dependent kinase-5 [PDF]

, 2003
Seth D. Norrholm, James Bibb, Eric J. Nestler, Charles C. Ouimet, Jane R. Taylor, Paul Greengard   +5 more
openalex   +1 more source

Long Term High‐Salt Diet Induces Cognitive Impairments via Down‐Regulating SHANK1

Advanced Science, EarlyView.
The study identifies a novel mechanistic link between long‐term HS diet and cognitive impairment, wherein PKA/CREB axis inactivation leads to SHANK1 reduction, synaptic damage, and cognitive deficits. Abstract High‐salt (HS) diet is an established risk factor for cognitive impairment, but the underlying mechanisms remain unclear.
Cuiping Guo, Yuanyuan Li, Wensheng Li, Tongrui Wu, Yi Liu, Yacoubou Abdoul Razak Mahaman, Jianzhi Wang, Rong Liu, Wei Liu, Hui Shen, Xiaochuan Wang   +10 more
wiley   +1 more source

Expression of synaptic proteins and development of dendritic spines in fetal and postnatal neocortex of the pig, the European wild boar Sus scrofa. [PDF]

Brain Struct Funct
Sobierajski E, Czubay K, Schmidt MR, Wiedenski S, Rettschlag S, Beemelmans C, Beemelmans C, Wahle P.   +7 more
europepmc   +1 more source

Local autocrine plasticity signaling in single dendritic spines by insulin-like growth factors. [PDF]

Sci Adv, 2023
Tu X, Jain A, Parra Bueno P, Decker H, Liu X, Yasuda R.   +5 more
europepmc   +1 more source