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Dendritic spines and linear networks

Journal of Physiology-Paris, 2004
The function of the cortical microcircuitry is still mysterious. Using a bottom-up analysis based on the biophysics and connectivity of cortical neurons, we propose the hypothesis that the neocortex is essentially a linear integrator of inputs. Dendritic spines would slow the neuron and contribute to linearize input summation.
Rafael, Yuste, Rochelle, Urban
openaire   +2 more sources

Regulation of dendritic spine stability

Hippocampus, 2000
Dendritic spines undergo several types of transformations, ranging from growth to collapse, and from elongation to shortening, and they experience dynamic morphological activity on a rapid time scale. Changes in spine number and morphology occur under pathological conditions like excitotoxicity, but also during normal central nervous system development,
F M, Smart, S, Halpain
openaire   +2 more sources

Electrical Compartmentalization in Dendritic Spines

Annual Review of Neuroscience, 2013
Most excitatory inputs in the CNS contact dendritic spines, avoiding dendritic shafts, so spines must play a key role for neurons. Recent data suggest that, in addition to enhancing connectivity and isolating synaptic biochemistry, spines can behave as electrical compartments independent from their parent dendrites. It is becoming clear that, although
openaire   +2 more sources

Dendritic Spines

2013
D. Muller, I. Nikonenko
openaire   +2 more sources

Integrative oncology: Addressing the global challenges of cancer prevention and treatment

Ca-A Cancer Journal for Clinicians, 2022
Jun J Mao,, Msce   +2 more
exaly  

Dendritic Spine

2010
Nicola Simola   +141 more
openaire   +1 more source

Dendritic Spines

1991
Valentino Braitenberg, Almut Schüz
openaire   +1 more source

Obesity and adverse breast cancer risk and outcome: Mechanistic insights and strategies for intervention

Ca-A Cancer Journal for Clinicians, 2017
Cynthia Morata-Tarifa   +1 more
exaly  

Multidisciplinary standards of care and recent progress in pancreatic ductal adenocarcinoma

Ca-A Cancer Journal for Clinicians, 2020
Aaron J Grossberg   +2 more
exaly  

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