Results 101 to 110 of about 183,701 (268)

Illness in Children Presenting to the Emergency Department After International Travel: A 10‐Year Retrospective Analysis From the University Hospital of Helsinki, Finland

Acta Paediatrica, EarlyView.
ABSTRACT Aim We characterized infections after international travel and identified predictors of severe infection to refine management. Methods We conducted a retrospective cross‐sectional analysis of children aged 0–18 years presenting to Helsinki University Hospital Emergency Department within 90 days of international travel between January 1, 2015 ...
Tuula Pelkonen, Svetlana Vakkilainen
wiley   +1 more source

RNAi-Induced Gene Silencing against Chikungunya and COVID-19: What Have We Learned So Far, and What Is the Way Forward?

Viruses
RNA interference (RNAi) is a process in which small RNA molecules (such as small interfering RNAs or siRNAs) bind to specific messenger RNAs (mRNAs), leading to its degradation and inhibition of protein synthesis.
Kingshuk Panda, Kalichamy Alagarasu, Rajarshee Tagore, Mandar Paingankar, Satyendra Kumar, Manish Kumar Jeengar, Sarah Cherian, Deepti Parashar   +7 more
doaj   +1 more source

Frayed Rope and Resilient Threads: Fijian Healthcare and the COVID‐19 Pandemic

Asia Pacific Viewpoint, EarlyView.
ABSTRACT In April 2021, Fiji faced international scrutiny due to ‘horrific’ hospital conditions, including staff and patients lacking food, non‐operational operating theatres, and critical shortages of beds, medicine, and equipment. After successfully avoiding a major outbreak in 2020, a sudden surge in COVID‐19 cases in 2021 overwhelmed the public ...
Sharon McLennan, Johanna Thomas‐Maude, Apisalome Movono, Akisi Ravono   +3 more
wiley   +1 more source

Lovastatin for adult patients with dengue: protocol for a randomised controlled trial. [PDF]

, 2012
BACKGROUND: Dengue is the most important vector-borne viral infection of man, with approximately 2 billion people living in areas at risk. Infection results in a range of manifestations from asymptomatic infection through to life-threatening shock and ...
Hien, Tran Tinh, Simmons, Cameron, Nguyen Van Hao, Tai, Luong Thi Hue, Marcel Wolbers, Truong, Nguyen Thanh, James Whitehorn, Rosanna Peeling, Peeling, Rosanna, Nguyen Thanh Truong, Tran Tinh Hien, Laura Merson, Nguyen Thi Phuong Dung, Wills, Bridget, Nguyen Van Vinh Chau, Cameron Simmons, Wolbers, Marcel, Bridget Wills, Farrar, Jeremy, Jeremy Farrar, Van Vinh Chau, Nguyen, Whitehorn, James, Merson, Laura, Van Hao, Nguyen, Luong Thi Hue Tai, Dung, Nguyen Thi Phuong   +25 more
core   +2 more sources

In the Spotlight—Established Researcher

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
Rodrigo Nunes‐da‐Fonseca
wiley   +1 more source

Health Research Funders and Justice: Obligations to Coordinate and Counterbalance

Bioethics, EarlyView.
ABSTRACT Government health research funders are frequently criticized on the grounds that their distribution of resources fails to reflect a population's disease burden. These critiques do not take into account what other research funders are doing. In this paper, I argue that this is a mistake.
Joseph Millum
wiley   +1 more source

Role of the chemokine receptors CCR1, CCR2 and CCR4 in the pathogenesis of experimental dengue infection in mice [PDF]

, 2010
Dengue virus (DENV), a mosquito-borne flavivirus, is a public health problem in many tropical countries. Recent clinical data have shown an association between levels of different chemokines in plasma and severity of dengue.
Mauro M Teixeira, Besnard, Anne-Gaëlle, Danielle G Souza, Fagundes, C.T., Teixeira, Mauro M, Guabiraba Rodrigo, Fagundes Caio T., Teixeira Mauro M., Anne-Gaëlle Besnard, Souza, Danielle G., Souza Danielle G., Danielle G. Souza, Mauro M. Teixeira, Teixeira, M.M., Caio T Fagundes, Ryffel Bernhard, Bernhard Ryffel, Souza, Danielle G, Besnard, A., Marques, Rafael Elias, Fagundes, Caio T., Ryffel, Bernhard, Rodrigo Guabiraba, Fagundes, Caio T, Marques Rafael Elias, Marques, R.E., Guabiraba, Rodrigo, Guabiraba Brito, R., Besnard Anne-Gaëlle, Rafael Elias Marques, Caio T. Fagundes   +30 more
core   +2 more sources

Dengue [PDF]

New England Journal of Medicine, 2012
Simmons, C, Farrar, J, Nguyen, V, Wills, B   +3 more
openaire   +5 more sources

Explorations on the antiviral potential of zinc and magnesium salts against chikungunya virus: implications for therapeutics

Frontiers in Cellular and Infection Microbiology
BackgroundChikungunya virus (CHIKV), which causes chikungunya fever, is an arbovirus of public health concern with no approved antiviral therapies. A significant proportion of patients develop chronic arthritis after an infection.
Kusuma Sai Davuluri, Shridhar Shukla, Mahadeo Kakade, Sarah Cherian, Sarah Cherian, Kalichamy Alagarasu, Kalichamy Alagarasu, Deepti Parashar, Deepti Parashar   +8 more
doaj   +1 more source

Phase 3, randomised, placebo‐controlled trial of voxelotor for the resolution of leg ulcers in sickle cell disease: RESOLVE

British Journal of Haematology, EarlyView.
In this trial, conducted in Kenya, Nigeria and Brazil, the resolution of leg ulcers was similar between the voxelotor and placebo arms. In the 12‐week blinded period, the number of sickle cell anaemia with crisis events was higher in the voxelotor arm compared to placebo.
Bernhards Ogutu, Janet Oyieko, Halima Bello‐Manga, Adeseye Akinsete, Jessie Githanga, José Valber Lima Meneses, Carolyn Hoppe, Mark W. Davis, Jeremy Rupon, Ching‐Ray Yu, Roberto Pinto, Elena Tudone, Ibrahim Musa Idris, Martin Meremikwu, Aderson da Silva Araújo, Rodolfo D. Cançado, Guilherme Fonseca, Patrícia Santos Resende Cardoso, Obiageli Eunice Nnodu, on behalf of the RESOLVE Investigators   +19 more
wiley   +1 more source