Results 111 to 120 of about 183,701 (268)

Determining the efficacy of guppies and pyriproxyfen (Sumilarv® 2MR) combined with community engagement on dengue vectors in Cambodia: study protocol for a randomized controlled trial

open access: yesTrials, 2017
Background Evidence on the effectiveness of low-cost, sustainable, biological vector-control tools for the Aedes mosquitoes is limited. Therefore, the purpose of this trial is to estimate the impact of guppy fish (guppies), in combination with the use of
John Hustedt   +13 more
doaj   +1 more source

Liver Organoids: From Disease Modelling to Regenerative Medicine

open access: yesCell Proliferation, EarlyView.
Liver organoids provide a versatile platform for disease modelling and drug discovery, leveraging stem cells and engineering techniques. They bridge research and clinical applications, offering significant potential for advancing precision medicine and regenerative therapies for liver diseases.
Tiepeng Wang   +5 more
wiley   +1 more source

Dengue virus inhibits alpha interferon signaling by reducing STAT2 expression [PDF]

open access: yes, 2005
Type 1 interferons (IFN-?/?) are key mediators of innate antiviral responses but havelittle effect on established replication of dengue viruses, which are mosquito-borneflaviviruses of immense global health importance.
Jones, M   +9 more
core   +1 more source

Risk Factors for Mortality in Dengue Shock Syndrome (DSS) [PDF]

open access: yes, 2009
Background: Dengue shock syndrome (DSS) is the most severe form of dengue hemorrhagic fever (DHF) and has a high mortality. There are two major pathological changes in DHF determining the severity of disease, plasma leakage and bleeding.
Djokomoeljanto, Robert J   +6 more
core   +1 more source

Early tocilizumab and outcomes in acute necrotizing encephalopathy

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
Early tocilizumab and outcome in acute necrotising encephalopathy. Aim To evaluate the timing and safety of tocilizumab in acute necrotizing encephalopathy (ANE). Method This was a multicentre retrospective study evaluating outcomes (modified Rankin Scale [mRS]) in children with ANE treated with tocilizumab. A logistic regression model determined a cut‐
Velda X Han   +14 more
wiley   +1 more source

Contribution of endosomal proteins EHD1 and EHD4 to the HIV‐1 replication cycle

open access: yesThe FEBS Journal, EarlyView.
EHD1 and EHD4, two key trafficking proteins, regulate multiple stages of HIV‐1 infection: In producer cells, they help produce fully infectious virus particles, regulate Envelope protein incorporation in a cell‐type‐dependent manner, and limit the accumulation of antiviral IFITM proteins in virions.
Grégory Pacini   +4 more
wiley   +1 more source

Dengue and Dengue Virus in Florida

open access: yesEDIS
This publication provides an overview of dengue fever, focusing on its epidemiological landscape in Florida. Dengue, caused by dengue virus and transmitted through the bites of infected Aedes mosquitoes, is a major global health concern. Florida has experienced local dengue transmissions, and the incidence of dengue is increasing in the state.
Yasmin V. Ortiz   +3 more
openaire   +1 more source

Conserved dimerization architecture in C‐type lectins from virus‐vector mosquitoes

open access: yesThe FEBS Journal, EarlyView.
C‐type lectins (CTLs) are involved in the detection of viral/microbial carbohydrates. We studied a family of soluble CTLs in the mosquito Aedes aegypti, which acts as a vector for viruses like dengue and Zika. Using crystallography, biophysics, and structure prediction approaches, we found that these proteins consistently pair together in the same ...
Mattia Bertinelli   +6 more
wiley   +1 more source

Diarrhea and dengue control in rural primary schools in Colombia: study protocol for a randomized controlled trial. [PDF]

open access: yes, 2012
BACKGROUND: Diarrheal diseases and dengue fever are major global health problems. Where provision of clean water is inadequate, water storage is crucial.
Vargas Sandra   +36 more
core   +2 more sources

Treating Dengue haemorrhagic fever with fixed flat rate of fluid and intermittent fluid boluses: Insights from a specialized dengue treatment centre

open access: yesInternational Journal of Infectious Diseases, 2020
L. Fernando   +9 more
doaj   +1 more source

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