Results 91 to 100 of about 183,701 (268)

Genome-wide association study identifies susceptibility loci for dengue shock syndrome at MICB and PLCE1. [PDF]

, 2011
Hypovolemic shock (dengue shock syndrome (DSS)) is the most common life-threatening complication of dengue. We conducted a genome-wide association study of 2,008 pediatric cases treated for DSS and 2,018 controls from Vietnam.
Tuan, NM, Long, H.T., Sarah J Dunstan, Gan, Tran Thi, Martin L Hibberd, Chau, T.N.B., Long, Hoang Truong, Van N Vinh Chau, Nguyen, Khor, C.C., Tuan, Nguyen Minh, Hieu, Nguyen Trong, Hong, Rick T. H., Wills, Bridget, Lanh, M.N., Tan, Dennis EK, Thuy, Tran Thi, Tham, NTH, Farrar, Jeremy, Gan, TT, Dunstan, Sarah, Dunstan, SJ, Pang, J., Nguyen Minh Tuan, Lien, LB, Tuan, N.M., Tran Thi Thuy, Davila, Sonia, Pang, J, Lanh, MN, Long, HT, Hoang Truong Long, Thuy, T.T., Sonia Davila, Binh, Nguyen Thi Nguyet, Simmons, Cameron P, Davila, S, Nguyen Trong Hieu, Tan, DEK, Ong, R.T.H., Tham, Nguyen Thi Hong, Le Bich Lien, Hibberd, ML, Sakuntabhai, A, Gan, T.T., Mai Ngoc Lanh, Van Tram, T, Anavaj Sakuntabhai, Dennis E K Tan, Teo, Yik-Ying, Binh, NTN, Nguyet, N.M., Tan, Dennis E. K., Hibberd, Martin L, Dunstan, Sarah J, Chau, Tran Nguyen Bich, Rick T H Ong, Teo, YY, Wills, B, Van N Vinh Chau, N, Wills, B., Simmons, Cameron P., Lien, L.B., Ta Van Tram, Tan, D.E.K., Chiea Chuen Khor, Pang, Junxiong, Ong, RTH, Nguyen Thi Nguyet Binh, Nguyen Minh Nguyet, Farrar, J, Nguyet, NM, van Vinh Chau, Nguyen, Jeremy Farrar, Khor, CC, Simmons, C.P., Nguyen Thi Hong Tham, Tri, Le Trung, Hibberd, M.L., Van Tram, Ta, Le Trung Tri, Simmons, CP, Tran Thi Gan, Sakuntabhai, A., Nguyet, Nguyen Minh, Van N Vinh Chau, N., Nguyen Van N Vinh Chau, Lanh, Mai Ngoc, Farrar, J., Hibberd, Martin, L., Binh, N.T.N., Junxiong Pang, Sakuntabhai, Anavaj, Khor, Chiea Chuen, Tri, L.T., Van Tram, T., Thuy, TT, Ong, Rick TH, Tran Nguyen Bich Chau, Bridget Wills, Yik-Ying Teo, Hieu, NT, Davila, S., Cameron P Simmons, Lien, Le Bich, Tri, LT, Chau, TNB, Tham, N.T.H., Hieu, N.T., Dunstan, S.J., Teo, Y.-Y.   +109 more
core   +1 more source

Estimating Dengue Outbreak Thresholds in West Africa: A Comprehensive Analysis of Climatic Influences in Burkina Faso, 2018–2024

Tropical Medicine and Infectious Disease
Background: Dengue, transmitted by Aedes spp. mosquitoes, poses significant public health challenges in Burkina Faso. This study investigated outbreak thresholds, utilizing historical data since 2018 to explore the climatic impacts on dengue transmission
John Otokoye Otshudiema, Watton R. Diao, Sonia Marie Wend-Kuuni Ouedraogo, Alain Ngoy Kapete, Laurent Moyenga, Emmanuel Chanda, Tieble Traore, Otim Patrick Ramadan, Alimuddin Zumla   +8 more
doaj   +1 more source

Key Amino Acid Substitution for Infection-Enhancing Activity-Free Designer Dengue Vaccines

iScience, 2019
Summary: Dengue is a globally important disease caused by four serotypes of dengue virus. Dengue vaccine development has been hampered by antigenic cross-reactivity among serotypes, which potentially causes antibody-dependent enhancement of infection and
Atsushi Yamanaka, Eiji Konishi
doaj   +1 more source

Microfluidic Molecular Diagnostic Chips: Functional Modules, Integration Strategies, and Emerging Applications

Small Methods, EarlyView.
This comprehensive review delivers an engineering‐centric analysis of microfluidic molecular diagnostic chips, breaking them down into foundational modules from fluid manipulation to bio‐sensing. Beyond chip design, it evaluates sample‐to‐answer integration strategies and commercial readiness levels.
Donghoon Koo, Egor Kokin, Sangyul Baik, Chanyong Park, Minji Kim, Jeongmin Kim, Ryungeun Song, Hosub Lim   +7 more
wiley   +1 more source

Impact of Environmental Microparticles on Insect Olfaction

Environmental Toxicology, EarlyView.
ABSTRACT Terrestrial insects underpin key ecosystem services, including pollination, herbivory regulation, decomposition, nutrient cycling, and disease control. These functions depend on chemical communication that guides insects to food, mates, hosts, shelters, and oviposition sites while helping them avoid threats.
Steve B. S. Baleba, Danube K. N. Wandji, Yves H. Tchiechoua, Komi Mensah Agboka, Iman B. Hassaballa, Victor O. Omondi, Beatrice T. Nganso, Saliou Niassy, Souleymane Diallo, Merid N. Getahun   +9 more
wiley   +1 more source

Exploring the Role of Pattern Recognition Receptors as Immunostimulatory Molecules

Immunity, Inflammation and Disease
Background Pattern recognition receptors (PRRs) are the receptors of the innate immune system that play a vital role in initiating innate immune response.
Meenal Sharma, Priyanka Wagh, Tanvi Shinde, Diptee Trimbake, Anuradha S. Tripathy   +4 more
doaj   +1 more source

Diagnostics for optimised dengue surveillance: a qualitative focus group study to investigate user experience and requirements in Thailand

BMJ Open
Objectives Effective, real-time surveillance of dengue may provide early warning of outbreaks and support targeted disease-control intervention but requires widespread accurate diagnosis and timely case reporting.
Raheelah Ahmad, Alison Holmes, Pantelis Georgiou, Paul Arkell, Sanhapon Ketklao, Adisak Songjaeng, Dumrong Mairiang, Jesus Rodriguez-Manzano, Prida Malasit, Panisadee Avirutnan, Saranath Lawpoolsri   +10 more
doaj   +1 more source

Multiple introductions of dengue virus strains contribute to dengue outbreaks in East Kalimantan, Indonesia, in 2015–2016

Virology Journal, 2019
Background Dengue fever is a febrile disease caused by dengue virus (DENV), which affects people throughout the tropical and subtropical regions of the world, including Indonesia.
R. Tedjo Sasmono, Lily Pertiwi Kalalo, Suryani Trismiasih, Dionisius Denis, Benediktus Yohan, Rahma F. Hayati, Sotianingsih Haryanto   +6 more
doaj   +1 more source

Iflaviruses in arthropods: when small is mighty

Insect Science, EarlyView.
Many arthropod species harbor iflaviruses, which often cause covert (asymptomatic) infections, but may still affect host fitness. We review the impact of iflaviruses on arthropod fitness, immunity, behaviour as well as the iflavirus’ host range, transmission, tissue tropism and the interactions with other microorganisms within arthropods.
Annamaria Mattia, Hannah‐Isadora Huditz, Monique M. van Oers, Vera I.D. Ros   +3 more
wiley   +1 more source

ANTIVIRAL ACTIVITY OF COPPER(II)CHLORIDE DIHYDRATE AGAINST DENGUE VIRUS TYPE-2 IN VERO CELL

Indonesian Journal of Tropical and Infectious Disease, 2017
Infection of dengue virus (DENV) was number of globally significant emerging pathogen. Antiviral dengue therapies ar importantly needed to control emerging dengue.
Teguh Hari Sucipto, Siti Churrotin, Harsasi Setyawati, Tomohiro Kotaki, Fahimah Martak, Soegeng Soegijanto   +5 more
doaj   +1 more source