Results 51 to 60 of about 70,237 (252)

Unveiling Novel Viral Diversity, Biogeography, and Host Networks in Wildlife Through High‐Throughput Sequencing Data Mining

Advanced Science, EarlyView.
Analysis of 57 536 high‐throughput sequencing datasets uncovers a vast, hidden world of viruses in wildlife. The researchers reveal significant geographic and host‐specific patterns of viruses, and their surprising cross‐species transmissions, such as avian flu viruses infecting goats.
Hai Wang, Yafei Meng, Xiaoyuan Chen, Xinyuan Cui, Qian Zuo, Na Han, Xianghui Liang, Xuejuan Shen, Caiwu Li, Desheng Li, Fumin Wang, Liangping He, Rujian Chen, Xingbang Lu, Wenjie You, Aiping Wu, Rui‐Ai Chen, Wu Chen, Chan Ding, Yongyi Shen   +19 more
wiley   +1 more source

Domperidone inhibits dengue virus infection by targeting the viral envelope protein and nonstructural protein 1

Scientific Reports
Dengue is a mosquito-borne disease caused by dengue virus (DENV) infection, which remains a major public health concern worldwide owing to the lack of specific treatments or antiviral drugs available.
Nuttapong Kaewjiw, Thanawat Thaingtamtanha, Damini Mehra, Wanida Chawnawa, Tanapan Prommool, Chunya Puttikhunt, Adisak Songjaeng, Kessiri Kongmanas, Panisadee Avirutnan, Prasit Luangaram, Chatchawan Srisawat, Sittiruk Roytrakul, Stephan A. Bäurle, Sansanee Noisakran   +13 more
doaj   +1 more source

Machine Learning‐Assisted Infectious Disease Detection in Low‐Income Areas: Toward Rapid Triage of Dengue and Zika Virus Using Open‐Source Hardware

Advanced Intelligent Discovery, EarlyView.
This study introduces an affordable machine learning platform for simultaneous dengue and zika detection using fluorine‐doped tin oxide thin films modified with gold nanoparticles and DNA aptamers. Designed for low‐cost, hardware‐limited devices (< $25), the model achieves 95.3% accuracy and uses only 9.4 kB of RAM, demonstrating viability for resource‐
Marina Ribeiro Batistuti Sawazaki, Bassam Bachour Junior, Marcelo Mulato, José Ilton de Oliveira Filho   +3 more
wiley   +1 more source

Fever in a traveler returning from the Amazon. Do not forget hepatitis A

IDCases, 2016
Travelers returning from the tropics with fever remain a diagnostic challenge. Fever and chills suggest malaria, but may be present in dengue, chikungunya and influenza, and splenomegaly favors malaria or typhoid fever.
Burke A. Cunha, Rina Seerke Teper, Muhammad Raza   +2 more
doaj   +1 more source

Modeling the effect of temperature on dengue virus transmission with periodic delay differential equations

Mathematical Biosciences and Engineering, 2020
Dengue fever is a re-emergent mosquito-borne disease, which prevails in tropical and subtropical regions, mainly in urban and peri-urban areas. Its incidence has increased fourfold since 1970, and dengue fever has become the most prevalent mosquito-borne
Haitao Song , Dan Tian , Chunhua Shan
doaj   +1 more source

Silica Nanoparticles as Multifunctional Platforms for Vaccine Delivery and Immune Modulation in Infectious Diseases

Advanced NanoBiomed Research, EarlyView.
Overview of the use of silica nanoparticles in vaccines against pathogens. Different kinds of vaccines against infectious diseases are currently using solid or mesoporous silica nanoparticles in their formulation. Silica microparticles and nanoparticles (SiNPs) have been studied as vehicles for vaccines.
Noe Juvenal Mendoza‐Ramírez, Julio García‐Cordero, Gabriela Navarro‐Tovar, Leticia Cedillo‐Barrón   +3 more
wiley   +1 more source

Dengue encephalitis

Muller Journal of Medical Sciences and Research, 2015
Presentation of dengue fever can range from asymptomatic infection to life-threatening dengue hemorrhagic fever and dengue shock syndrome. We report a case of dengue fever presenting as encephalitis, which is very rare.
Amit A Bharadiya, Jyotsna B Jaju, Swati C Aundhakar, Makarand Mane, Vikrant Mahajani   +4 more
doaj   +1 more source

Economic burden of dengue fever in China: A retrospective research study.

PLoS Neglected Tropical Diseases, 2022
BackgroundDengue fever has been a significant public health challenge in China. This will be particularly important in the context of global warming, frequent international travels, and urbanization with increasing city size and population movement.
Meng Xu, Nan Chang, Taotian Tu, Jimin Sun, Jinyong Jiang, Yu Xia, Wenge Tang, Hengqing Ji, Xiaotao Zhao, Jin Zhu, Li Qi, Xiaobo Liu, Qiyong Liu   +12 more
doaj   +1 more source

AgamOBP1‐Directed Discovery of Repellents to Control the Spread of Mosquito‐Borne Diseases

ChemMedChem, EarlyView.
Toward the discovery of novel mosquito repellents, a library of potential binders of AgamOBP1 (secondary amines) generated from two amines and seven aldehydes was designed aiming to enable interactions with critical amino acids at the DEET‐site and to bridge the DEET‐ and Icaridin sIC‐binding pockets. 1H STD NMR spectroscopy in the presence of AgamOBP1
Evanthia Chazapi, Eftichia Kritsi, Constantinos Potamitis, Panagiota G. V. Liggri, Katerina E. Tsitsanou, Christina E. Drakou, Antonios Michaelakis, Dimitrios P. Papachristos, Spyros E. Zographos, Maria Zervou, Theodora Calogeropoulou   +10 more
wiley   +1 more source

Validity and Usefulness of Revised WHO Guidelines in Children with Dengue Fever [PDF]

Journal of Clinical and Diagnostic Research, 2018
Introduction: Dengue fever is the most rapidly spreading mosquito borne viral infection with a 30-fold increase in the disease burden over last five decades with a variable clinical course and outcome.
Sriram Pothapregada, Vijayalakshmi Sivapurapu, Banupriya Kamalakannan, Mahalakshmy Thulasingham   +3 more
doaj   +1 more source