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INTRODUCTION: Dengue is a vector-borne viral infection that endangers an estimated 2.5 billion people. Disease caused by dengue ranges from a relatively minor febrile illness to a life-threatening condition characterized by extensive capillary leak.
Whitehorn, J +6 more
core +1 more source
Background: Dengue is an important public health problem worldwide. A vaccine has recently been licensed in some countries of Latin America and Asia. Recommendations for dengue vaccine introduction include endemicity and a high serological prevalence of ...
Mabel Carabali +9 more
doaj +1 more source
Monoclonal antibody-based capture ELISA in the diagnosis of previous dengue infection
Background Dengue is an important mosquito-borne disease. There is currently only one licensed vaccine for dengue prevention. The vaccine provides higher efficacy in pre-vaccination dengue-seropositive persons but a higher risk of subsequent more severe ...
Chukiat Sirivichayakul +7 more
doaj +1 more source
Analysis of the optimal vaccination age for dengue in Brazil with a tetravalent dengue vaccine [PDF]
In this paper we study a mathematical model to analyse the optimal vaccination age against Dengue in Brazil. Data from Brazil are used to estimate the basic reproduction numbers for each of the four Dengue serotypes and then the optimal vaccination age is calculated using a method due to Hethcote [1].
Maier, Sandra B. +5 more
openaire +5 more sources
Dengvaxia: the world’s first vaccine for prevention of secondary dengue
The objective of this manuscript was to review and evaluate the efficacy and safety data of Dengvaxia for the treatment of severe secondary dengue infection. Dengvaxia is the brand name for chimeric yellow fever-dengue-tetravalent dengue vaccine (CYD-TDV)
Danielle Tully, Carrie L. Griffiths
doaj +1 more source
Molecular epidemiology of dengue viruses from complete genome sequences [PDF]
The availability of the complete genetic blueprint of the dengue virus is essential in molecular epidemiological studies to uncover the role of the virus in dengue pathogenesis.
Ong, Swee Hoe
core +1 more source
Background Dengue is the most rapidly spreading viral vector-borne disease in the world. Promising new dengue vaccines have contributed to a growing consensus that effective dengue control will require integrated strategies of vaccination and vector ...
Valerie K. Scott +3 more
doaj +1 more source
Dengue is an arthropod-borne infection caused by a flavivirus and spread by the Aedes mosquitoes. Many of the countries where dengue is endemic are popular tourist destinations and the disease is an increasingly important problem encountered by international travelers.
Annelies, Wilder-Smith +1 more
openaire +2 more sources
Dengue has emerged as one of the major global public health problems. The disease has broken out of its shell and has spread due to increased international travel and climatic changes. Globally, over 2.5 billion people accounting for >40% of the world's population are at risk from dengue.
Harashish, Jindal +3 more
openaire +2 more sources
Dengue virus activates polyreactive, natural IgG B cells after primary and secondary infection. [PDF]
BACKGROUND: Dengue virus is transmitted by mosquitoes and has four serotypes. Cross-protection to other serotypes lasting for a few months is observed following infection with one serotype.
Low, Jenny G. +62 more
core +2 more sources

