Results 31 to 40 of about 436,511 (214)
Dengue Vector Dynamics in Pakistan [PDF]
During the last few year dengue has become an emerging vector borne disease in Pakistan. Aedes aegypti once considered eradicated from almost whole of Pakistan was again collected from 13 different cities.
Rasheed, Syed Basit
core +6 more sources
Dengue is globally the most important arboviral infection of humans with an estimated 100 million infections per annum and 2.5 billion people at risk in >100 countries. The burden of dengue is substantial in economic terms and in the strain it places on already fragile health systems.
Jamie Whitehorn, Cameron P Simmons
openaire +1 more source
Estimates of dengue force of infection in children in Colombo, Sri Lanka. [PDF]
Dengue is the most important vector-borne viral disease worldwide and a major cause of childhood fever burden in Sri Lanka, which has experienced a number of large epidemics in the past decade.
Harold S Margolis +26 more
core +2 more sources
Bioethics of establishing a CHIM model for dengue vaccine development
Introduction: Controlled human infection models (CHIM) have been used in vaccine development to up-select and down-select potential vaccine candidates and to provide proof of vaccine efficacy, and have also been used as a basis for licensure of vaccines ...
Anuradha Rose, Amrita Sekhar
doaj +1 more source
With one vaccine on the market and others in clinical trials, policy makers in dengue endemic regions face the decision of whether to introduce a dengue vaccine in their communities.
Elizabeth McMahon +14 more
doaj +1 more source
Dengue virus inhibits alpha interferon signaling by reducing STAT2 expression [PDF]
Type 1 interferons (IFN-?/?) are key mediators of innate antiviral responses but havelittle effect on established replication of dengue viruses, which are mosquito-borneflaviviruses of immense global health importance.
Jones, M +9 more
core +1 more source
Dengue vaccine development: Global and Indian scenarios
India is home to nearly a third of the global population at risk of dengue, a viral disease caused by four antigenically and genetically distinct dengue viruses.
Sathyamangalam Swaminathan, Navin Khanna
doaj +1 more source
Development of MVA-d34 Tetravalent Dengue Vaccine: Design and Immunogenicity
Dengue fever, an infectious disease that affects more than 100 million people every year, is a global health problem. Vaccination may be the most effective prevention strategy for the disease.
Ramil R. Mintaev +6 more
doaj +1 more source
Outlook for a dengue vaccine [PDF]
Dengue is an increasing medical problem in subtropical and tropical countries. The search for a safe and effective vaccine is complicated by the fact that there are four types of dengue virus and that, if a vaccine is live attenuated, it should be proven not to cause the life-threatening form of dengue, dengue haemorrhagic fever.
openaire +2 more sources
Vaccines licensed and in clinical trials for the prevention of dengue
Dengue has become a major global public health threat with almost half of the world's population living in at-risk areas. Vaccination would likely represent an effective strategy for the management of dengue disease in endemic regions, however to date ...
J. Torresi, G. Ebert, M. Pellegrini
doaj +1 more source

