ChemistryOpen, EarlyView.A library of easily synthesizable CAPE analogs was screened in silico against the dengue virus envelope protein. Compound LQM778 showed stable binding and promising inhibitory potential. This study highlights LQM778 as a candidate for future in vitro validation and structural optimization toward accessible antiviral agents against dengue.
Luis Alfonso Cárdenas‐Granados +9 more
openalex +2 more sources
Virology Journal, 2008 Background Co-circulation of multiple dengue virus serotypes has been reported from many parts of the world including India, however concurrent infection with more than one serotype of dengue viruses in the same individual is rarely documented.
Guleria Randeep +7 more
doaj +1 more source
SAGE Open Medical Case Reports, 2021 Central nervous system involvement of dengue virus is increasingly reported from endemic areas. This study describes the clinical characteristics and laboratory features of a pediatric patient enrolled in a central nervous system illness study conducted ...
Dewi Hawani Alisjahbana +10 more
doaj +1 more source
Molecular typing of dengue viruses circulating in Assam, India during 2016–2017
Journal of Vector Borne Diseases, 2020 Background & objectives: The global incidence of dengue has grown dramatically in recent decades and Assam, India has witnessed several outbreaks of dengue since 2015.
A Sharma +6 more
doaj +1 more source
RNA sensors enable human mast cell anti-viral chemokine production and IFN-mediated protection in response to antibody-enhanced dengue virus infection. [PDF]
PLoS ONE, 2012 Dengue hemorrhagic fever and/or dengue shock syndrome represent the most serious pathophysiological manifestations of human dengue virus infection.
Michael G Brown +6 more
doaj +1 more source
The Epidemiology, Virology and Clinical Findings of Dengue Virus Infections in a Cohort of Indonesian Adults in Western Java. [PDF]
PLoS Neglected Tropical Diseases, 2016 Dengue has emerged as one of the most important infectious diseases in the last five decades. Evidence indicates the expansion of dengue virus endemic areas and consequently the exponential increase of dengue virus infections across the subtropics.
Herman Kosasih +15 more
doaj +1 more source
Lipidated dengue-2 envelope protein domain III independently stimulates long-lasting neutralizing antibodies and reduces the risk of antibody-dependent enhancement. [PDF]
PLoS Neglected Tropical Diseases, 2013 BACKGROUND: Dengue virus is a mosquito-transmitted virus that can cause self-limiting dengue fever, severe life-threatening dengue hemorrhagic fever and dengue shock syndrome.
Chen-Yi Chiang +9 more
doaj +1 more source
The Role Activity of Complement, TNFα & IL12 in Pathogenesis Dengue Virus
Indonesian Journal of Tropical and Infectious Disease, 2010 Dengue Virus infection is always found in some part of the world especially South East Asia including Indonesia. The pathogenesis of Dengue Virus infection is still controversial.
Soegeng Soegijanto +3 more
doaj +1 more source
Development of Dengue virus type 2 replicons capable of prolonged expression in host cells
BMC Microbiology, 2001 Background As part of a program to develop a Dengue virus vaccine which avoids the deleterious effects of antibody dependent enhancement (ADE) of infection mediated by antibodies to Dengue virus structural proteins, we have begun to investigate the ...
Dayton Andrew I +2 more
doaj +1 more source
System Analysis of Dengue Virus Surveillance in BBTKL PP Surabaya Year 2012–2014
Jurnal Berkala Epidemiologi, 2015 Changing the distribution of dengue virus serotypes has occurred in Indonesia. This condition should be monitored continuously through the Dengue Virus Surveillance. Implementation of Dengue Virus Surveillance also conducted by BBTKL PP Surabaya.
Atina Husnayain +2 more
doaj +1 more source