Revealing the molecular signatures of host-pathogen interactions. [PDF]
Advances in sequencing technology and genome-wide association studies are now revealing the complex interactions between hosts and pathogen through genomic variation signatures, which arise from evolutionary co ...
C Herdtweck +53 more
core +21 more sources
Dengue Virus Infection: A Tale of Viral Exploitations and Host Responses
Dengue is a mosquito-borne viral disease (arboviral) caused by the Dengue virus. It is one of the prominent public health problems in tropical and subtropical regions with no effective vaccines.
Nikita Nanaware +4 more
doaj +1 more source
SUMOylation Is Essential for Dengue Virus Replication and Transmission in the Mosquito Aedes aegypti
Small ubiquitin-like modifier (SUMO) is a reversible post-translational protein modifier. Protein SUMOylation regulates a wide variety of cellular processes and is important for controlling virus replication.
Shih-Che Weng, Shin-Hong Shiao
doaj +1 more source
Comparative susceptibility of mosquito populations in North Queensland, Australia to oral infection with dengue virus. [PDF]
Dengue is the most prevalent arthropod-borne virus, with at least 40% of the world's population at risk of infection each year. In Australia, dengue is not endemic, but viremic travelers trigger outbreaks involving hundreds of cases.
Anderson +47 more
core +2 more sources
Episode of coexisting infections with multiple dengue virus serotypes in central Karnataka, India
Summary: Background: The co-circulation of multiple dengue virus serotypes has been reported in many parts of the world, including India; however, concurrent infection with more than one serotype of dengue virus in the same individual is rarely ...
C.S. VinodKumar +6 more
doaj +1 more source
Immunogenicity of NS4b dengue 3 virus mimotope presented to the immune system as multiple antigen peptide system [PDF]
The availability of random peptide libraries displayed on bacteriophage (RPL) has provided a powerful tool for selecting sequences that mimic binding properties of natural antigen epitopes (mimotopes). These mimotopes can be used for vaccine design, drug
Acosta, Armando +11 more
core +2 more sources
Class II ADP-ribosylation factors are required for efficient secretion of Dengue viruses [PDF]
This article is available open access through the publisher’s website.Identification and characterization of virus-host interactions are very important steps toward a better understanding of the molecular mechanisms responsible for disease progression ...
Brault, JB +9 more
core +3 more sources
THE CHANGING CLINICAL PERFORMANCE OF DENGUE VIRUS INFECTION IN THE YEAR 2009
Background: Dengue (DEN) virus, the most important arthropod-borne human pathogen, represents a serious public health threat. DEN virus is transmitted to humans by the bite of the domestic mosquito, Aedes aegypti, and circulates in nature as four ...
Soegeng Soegijanto +4 more
doaj +1 more source
Chimeric Yellow Fever/Dengue Virus as a Candidate Dengue Vaccine: Quantitation of the Dengue Virus-Specific CD8 T-Cell Response [PDF]
We have constructed a chimeric yellow fever/dengue (YF/DEN) virus, which expresses the premembrane (prM) and envelope (E) genes from DEN type 2 (DEN-2) virus in a YF virus (YFV-17D) genetic background. Immunization of BALB/c mice with this chimeric virus
Ahmed, Rafi +3 more
core +2 more sources
FEVER AS INDICATOR TO SECONDARY INFECTION IN DENGUE VIRAL INFECTION
Dengue Virus Infections are distributed in tropical and sub-tropical regions and transmitted by the mosquitoes such as Aedes aegypti and Aedes albopictus.
Soegeng Soegijanto +3 more
doaj +1 more source

