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Immunopathogenesis of dengue virus infection
Dengue virus infection causes dengue fever (DF), dengue hemorrhagic fever (DHF), and dengue shock syndrome (DSS), whose pathogeneses are not clearly understood. Current hypotheses of antibody-dependent enhancement, virus virulence, and IFN-gamma/TNFalpha-mediated immunopathogenesis are insufficient to explain clinical manifestations of DHF/DSS such as ...
Shun-Hua Chen +2 more
exaly +3 more sources
Dengue Vector Dynamics in Pakistan [PDF]
During the last few year dengue has become an emerging vector borne disease in Pakistan. Aedes aegypti once considered eradicated from almost whole of Pakistan was again collected from 13 different cities.
Rasheed, Syed Basit
core +6 more sources
Investigation of denugue virus envelope gene quasispecies variation in patient samples : implications for virus virulence and disease pathognesis [PDF]
Due to the error-prone nature of RNA virus replication, each dengue virus (DV) exists as a quasispecies within the host. To investigate the hypothesis that DV quasispecies populations affect disease severity, serum samples were obtained from dengue ...
Love, Hannah
core +7 more sources
Dengue Virus and Autophagy [PDF]
Several independent groups have published that autophagy is required for optimal RNA replication of dengue virus (DENV). Initially, it was postulated that autophagosomes might play a structural role in replication complex formation. However, cryo-EM tomography of DENV replication complexes showed that DENV replicates on endoplasmic reticulum (ER ...
Heaton, Nicholas S., Randall, Glenn
openaire +3 more sources
Molecular Analysis of Dengue Virus Serotypes Circulating in Chennai, Tamil Nadu, India [PDF]
Introduction: Dengue fever is one of the most important arboviral infections all over the world. Globally, 50% of the human population is at risk of dengue virus infection.
Aridass Dhanasezhian +4 more
doaj +1 more source
Aedes aegypti is the most dominant vector in the transmission of dengue hemorrhagic fever (DHF). In addition to Ae. aegypti, Ae. albopictus is a secondary vector of the dengue virus, and both species are widespread in Indonesia.
Nia Kurnia +5 more
doaj +1 more source
Original antigenic sin in dengue - Hoskins effect
Dengue is a mosquito-borne viral infection found in tropical and subtropical climates worldwide, mostly in urban and semiurban areas. The virus responsible for causing dengue is called dengue virus. There are four dengue virus serotypes, implying that it
Vasantha Kamath, Nisha Davy Olakkengi
doaj +1 more source
Fighting the Dengue Virus [PDF]
The incidence of dengue has been on the upsurge in the last decade. It has affected around one-third of the world's population living in endemic areas. It can be asymptomatic or may present with some specific symptoms. No control measures have proven beneficial to decrease the prevalence of this disease.
Faraz, Aniqa +2 more
openaire +2 more sources
Dengue is the most prevalent arthropod-borne virus affecting humans today. The virus group consists of 4 serotypes that manifest with similar symptoms. Dengue causes a spectrum of disease, ranging from a mild febrile illness to a life-threatening dengue hemorrhagic fever.
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Secondary infection with the dengue virus causes mild to severe manifestations. The distribution of dengue virus serotypes varies in various areas and can change over time.
Annelin Kurniati +4 more
doaj +1 more source

