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Dense deposit disease—A 2011 update
R.J.H. Smith +9 more
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Dense deposit disease: new insights
Current Opinion in Nephrology and Hypertension, 2007Dense deposit disease is a rare but devastating disease primarily affecting children. This review focuses on new information regarding the pathophysiology of dense deposit disease, its appearance histopathologically, its relationship to other diseases including macular degeneration and acquired partial lipodystrophy and potential new therapies.The ...
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Spontaneous clinical improvement in dense deposit disease
Pediatric Nephrology, 2000The clinical course and 3-year follow-up of a female patient aged 11 years who presented with nephrotic syndrome and renal failure is described. The renal biopsy revealed type II membranoproliferative glomerulonephritis or dense deposit disease. She was treated with penicillin prophylaxis, frusemide and captopril, and was not given immunosuppression ...
S D, Marks, L, Rees
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APMIS, 1993
A membranoproliferative glomerulonephritis (MPGN) was diagnosed in 10 Yorkshire piglets, aged between 33 and 73 days, that had been submitted for routine autopsy. Matings of animals related to these piglets subsequently produced 15 offspring that had a membranoproliferative glomerulonephritis when examined at between 5 and 48 days of age. The principal
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A membranoproliferative glomerulonephritis (MPGN) was diagnosed in 10 Yorkshire piglets, aged between 33 and 73 days, that had been submitted for routine autopsy. Matings of animals related to these piglets subsequently produced 15 offspring that had a membranoproliferative glomerulonephritis when examined at between 5 and 48 days of age. The principal
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Recurrent dense deposit disease in renal allograft
Urology, 1978This report documents the recurrence of dense deposit disease in a renal allograft thirty-three days post-transplantation and stresses the usefulness of immunofluorescence in early detection.
A F, Jukkola +3 more
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Dense Deposit Disease: What Makes the Deposits Dense
Journal of the American Society of Nephrology, 2023Lilian M. Palma +2 more
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Granular dense deposit disease.
Laboratory investigation; a journal of technical methods and pathology, 1979During a retrospective study of dense deposit disease, we observed in three patients, unusual granular electron-dense deposits in the glomerular basement membrane in a laminar pattern. However, the distribution of these electron-dense deposits was similar to the distribution of the homogeneous, extremely electron-dense deposits of dense deposit disease.
J T, King +3 more
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Partial lipoatrophy in dense deposit disease
Kidney International, 2020Gopalakrishnan, Natarajan +4 more
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Seeing through the density of dense deposit disease
Kidney InternationalLittle is known about what constitutes the dense deposits of dense deposit disease (DDD), apart from components of the complement pathway. This study presents the novel finding that large accumulations of apolipoprotein E are present in the deposits of DDD, as revealed by mass spectroscopy and confirmed by both confocal microscopy and ...
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