Results 41 to 50 of about 238 (213)

Time Processing of Signals of NE102 and Stilbene Plastic Scintillator Detectors in Detecting Emission of Beams from Plasma Focus Device [PDF]

فیزیک کاربردی ایران
The plasma focus device is a pulsed source of soft X-ray (SXR), hard X-ray (HXR), ion beam, electron beam, and neutrons. In order to detect SXR, HXR, and neutrons, plastic scintillator detectors with different crystals are used.
Amir Raeisdana
doaj   +1 more source

Application of dense plasma focus devices and lasers in the radiation material sciences for the goals of inertial fusion beyond ignition

Matter and Radiation at Extremes, 2020
Specimens of materials for prospective use in chambers of nuclear fusion reactors with inertial plasma confinement, namely, W, ODS steels, Eurofer 97 steel, a number of ceramics, etc., have been irradiated by dense plasma focus ...
V. A. Gribkov, I. V. Borovitskaya, E. V. Demina, E. E. Kazilin, S. V. Latyshev, S. A. Maslyaev, V. N. Pimenov, T. Laas, M. Paduch, S. V. Rogozhkin   +9 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Hard X-Ray Emission Detection Using Deep Learning Analysis of the Radiated UHF Electromagnetic Signal From a Plasma Focus Discharge

IEEE Access, 2019
A method to determine the presence of hard X-ray emission processes from a dense plasma focus (205 J, 22 kV, 6.5 mbar H2) using Ultra High Frequency (UHF) measurements and deep learning techniques is presented.
Gonzalo Avaria, Jorge Ardila-Rey, Sergio Davis, Luis Orellana, Benjamin Cevallos, Cristian Pavez, Leopoldo Soto   +6 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

Development of a Miniaturized 2-Joule Pulsed Plasma Source Based on Plasma Focus Technology: Applications in Extreme Condition Materials and Nanosatellite Orientation

Micromachines
Plasma focus devices represent a class of hot and dense plasma sources that serve a dual role in fundamental plasma research and practical applications.
Leopoldo Soto, Cristian Pavez, José Pedreros, Jalaj Jain, José Moreno, Patricio San Martín, Fermín Castillo, Daniel Zanelli, Luis Altamirano   +8 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Double 3 MJ dense plasma focus for thermonuclear drive inertial confinement fusion

Scientific Reports
Nuclear fusion remains one of the most promising solutions for clean and sustainable energy production. However, significant challenges—including energy losses, plasma instabilities, and high operational costs—continue to hinder its practical realization.
S. M. Sadat Kiai, Shirin Adlparvar, Hossein Sadeghi, Samaneh Fazelpour   +3 more
doaj   +1 more source