Results 51 to 60 of about 238 (213)

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Dysregulated lipid metabolism links NAFLD to cardiovascular disease

Molecular Metabolism, 2020
Background: Non-alcoholic fatty liver disease (NAFLD) is rapidly becoming a global health problem. Cardiovascular diseases (CVD) are the most common cause of mortality in NAFLD patients.
Audrey Deprince, Joel T. Haas, Bart Staels   +2 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

ALEGRA-HEDP simulations of the dense plasma focus. [PDF]

, 2009
We have carried out 2D simulations of three dense plasma focus (DPF) devices using the ALEGRA-HEDP code and validated the results against experiments. The three devices included two Mather-type machines described by Bernard et. al. and the Tallboy device currently in operation at NSTec in North Las Vegas.
Flicker, Dawn G., Kueny, Christopher S. (Hewlett-Packard Company), Rose, David V.   +3 more
openaire   +2 more sources

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Study of The Dynamical Behavior For Deuterons in Dense Plasma Focus

Ibn Al-Haitham Journal for Pure and Applied Sciences, 2017
    The motion of fast deuterons in most dense plasma focus devices  ( DPF ) , may be characterized that it has a complex nature in its paths and this phenomena by describing a through gyrating motion with arbitrary changes in magnitude and direction . 
D. H. Yonas, R.H. Majeed
doaj  

The effect of a gas type on the soft X-ray yield from a plasma focus

St. Petersburg Polytechnical University Journal: Physics and Mathematics
Using the Lee code version (RADPFV5.15de), we carried out a series of numerical ‎experiments to find the parameters for the plasma focus and the soft X-ray yield for each of ‎nitrogen gas (molecular) and neon gas (atomic) within an appropriate ...
Nassif Alaa, Sahyouni Walid, Zeidan Ola
doaj   +1 more source

Quantitative Determination of Cellular-and Neurite Motility Speed in Dense Cell Cultures

Frontiers in Neuroinformatics, 2019
Mobility quantification of single cells and cellular processes in dense cultures is a challenge, because single cell tracking is impossible. We developed a software for cell structure segmentation and implemented 2 algorithms to measure motility speed ...
Andreas W. Henkel, Lulwa A. A. D. Al-Abdullah, Mohammed S. Al-Qallaf, Zoran B. Redzic   +3 more
doaj   +1 more source

Magnetically Induced Plasma Rotation and the Dense Plasma Focus

Zeitschrift für Naturforschung A, 1983
Abstract Fusion for Fission fuel breeding and other incentives for unconventional magnetic fusion research are introductorily mentioned. The design, operation and peculiar characteristics of dense plasma foci are briefly described with attention to their remarkable ion acceleration and plasma heating capabilities.
openaire   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source