Results 71 to 80 of about 50,398 (301)

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Damage Studies of Tungsten Samples Using Dense Plasma Focus Devices [PDF]

, 2020
Design and studies of plasma facing material for a fusion reactor is an engineering challenge. The focus of this M.Sc. thesis research project studies the interaction between the helium (He) ion beam produced in a dense plasma focus (DPF) device and the ...
Sharma, Priya
core  

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Investigations on the transition between colomn and micropinch mode of plasma focus operation

, 2022
S.324-331 : Abb.,Tab.,Lit.In plasma focus devices operated with pure nitrogen, neon or argon (Z equal or smaller than 18) with pinch current from 200 to 400 kA the emitting region is a column with several 100 mym in diameter and several mm in length ...
Engel, A., Neff, W., Gäbel, K., Lebert, R., Rothweiler, D., Förster, E.   +5 more
core  

Magnetically Induced Plasma Rotation and the Dense Plasma Focus

Zeitschrift für Naturforschung A, 1983
Abstract Fusion for Fission fuel breeding and other incentives for unconventional magnetic fusion research are introductorily mentioned. The design, operation and peculiar characteristics of dense plasma foci are briefly described with attention to their remarkable ion acceleration and plasma heating capabilities.
openaire   +1 more source

Fully three-dimensional simulation and modeling of a dense plasma focus [PDF]

The Journal of Defense Modeling and Simulation: Applications, Methodology, Technology, 2014
A dense plasma focus (DPF) is a pulsed-power machine that electromagnetically accelerates and cylindrically compresses a shocked plasma in a Z-pinch. The pinch results in a brief (~ 100 ns) pulse of X-rays, and, for some working gases, also a pulse of neutrons.
Meehan, B. T., Niederhaus, J. H. J.
openaire   +2 more sources

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Dense Plasma Focus: physics and applications (radiation material science, single-shot disclosure of hidden illegal objects, radiation biology and medicine, etc.) [PDF]

, 2015
The paper presents some outcomes obtained during the year of 2013 of the activity in the frame of the International Atomic Energy Agency Co-ordinated research project "Investigations of Materials under High Repetition and Intense Fusion-Relevant Pulses".
Gribkov, V. A, Talab, A, Pytel, K, Tomaszewski, K, GIANNINI, GIANROSSANO, Cicuttin, A, Skladnik Sadowska, E, NIEMELA, JOSEPH JAMES, Pimenov, V. N, LONGO, FRANCESCO, Chernyshova, M, Zielinska, E, Demina, E. V, Miklaszewski, R, Sadowski, M. J, Pisarczyk, T, Zawadka, A, Ul'Yanenko, S. E., Crespo, M. L, Paduch, M   +19 more
core   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source