Results 211 to 220 of about 224,534 (289)

BEX2 regulates autophagy by inhibiting PIK3CA-p85 interaction in non-small-cell lung cancer cells. [PDF]

Cell Commun Signal
Wang Y, Mu N, Wang X, Liu J, Qu Y, Liu X, Su L.   +6 more
europepmc   +1 more source

Resistance‐exercise‐induced stress intervenes in TGF‐β signaling by cooperatively downregulating nuclear αB‐crystallin and SMAD4 in human skeletal muscle fibers

The FEBS Journal, EarlyView.
Alpha‐crystallin B chain (CRYAB) has been reported to stabilize mothers against decapentaplegic homolog 4 (SMAD4) in transforming growth factor‐β (TGF‐β) signaling, enabling target gene transcription. We show nuclear CRYAB–SMAD4 interaction for the first time in human skeletal muscle fibers and its regulation by exercise.
Kirill Schaaf, Cassandra Duda, Tihomir Kostov, Patrick Diel, Käthe Bersiner, Wilhelm Bloch, Sebastian Gehlert, Daniel Jacko   +7 more
wiley   +1 more source

Acute Intermittent Hypoxia Exerts Beneficial Effects and Promotes Repair in Male Mice in the Experimental Autoimmune Encephalomyelitis Model of Multiple Sclerosis. [PDF]

Glia
Tokarska N, Roberts J, Koralage SR, Naniong JMA, Johnston JM, Wei Z, Verge VMK.   +6 more
europepmc   +1 more source

Investigation into the delivery and evaluation of a unique Avena sativa (Oat) Lipid Extract on skin barrier using LC‒MS/MS, Raman spectroscopy, immunostaining analysis and skin efficacy

International Journal of Cosmetic Science, EarlyView.
Abstract Objectives Oat lipids are rich in ceramides. In this investigation, we analysed the delivery of a specific Oat Lipid Extract derived from Avena sativa, comprising ‘skin identical’ ratios of fatty acids, ceramides and cholesterol/sterol. This investigation is the first reported investigation of oat lipids utilizing Raman spectroscopy for the ...
E. Gombert, C. Dewis
wiley   +1 more source

Smartphone-assisted HPTLC for simultaneous determination of vonoprazan fumarate and aspirin: a comparative study with HPTLC densitometry. [PDF]

Sci Rep
Hammad SF, Hamid MAA, Elagamy SH, Adly L.   +3 more
europepmc   +1 more source

TREM‐1 Blockade Inhibits Inflammasome Activation and Pyroptosis: Novel Insights on the Role of TREM‐1 and Syk in Monosodium Urate Crystal‐Induced Inflammation

Immunology, EarlyView.
Schematic overview of the roles triggering receptor expressed on myeloid cells‐1 (TREM‐1) plays in monosodium urate (MSU) crystal‐induced inflammasome activation and IL‐1β secretion in gout arthritis. The present study provides novel data suggesting that blockade of TREM‐1 by LP17 attenuates MSU‐crystal‐induced inflammation through inhibition of ...
Yair Molad, Irina Lagovsky, Vitaly Kliminski   +2 more
wiley   +1 more source

Correction to: Vertebral fracture prevalence and risk factors for fracture in The Gambia, West Africa: the Gambian Bone and Muscle Ageing Study. [PDF]

J Bone Miner Res
europepmc   +1 more source

AUM-302, a novel triple PIM/PI3K/mTOR inhibitor, synergizes with RAS inhibition and impedes the growth of pancreatic ductal adenocarcinoma spheroids and organoids. [PDF]

Front Pharmacol
Wen E, Vera C, Kesavan S, Kouassi F, LaComb JF, Zand N, Tuveson DA, Habowski AN, Baines AT, Bialkowska AB.   +9 more
europepmc   +1 more source

Thriving in Nursing Work: The Association Between Self‐Reports and Biomarkers of Stress, Inflammation and Neuroplasticity

Journal of Advanced Nursing, EarlyView.
ABSTRACT Aim To examine whether self‐reported thriving at work is associated with biomarkers of stress, inflammation, neuroplasticity and neurodegeneration in nurses. Design A cross‐sectional study. Methods An online questionnaire measuring thriving at work was administered to nurses in a teaching hospital in Michigan, U.S. over 5 weeks in 2024.
Judith E. Arnetz, Eamonn Arble, Jackeline Iseler, Michelle Pena, Nicolina Evola, John Vanschagen, John S. Beck, Scott E. Counts, Bengt B. Arnetz   +8 more
wiley   +1 more source

PRRSV Nsp11 antagonizes host antiviral immune response by reducing OAS1 and RNase L expressions. [PDF]

BMC Vet Res
Jiang D, Wang X, Sui C, Wu X, Hu Y, Cong X, Li J, Qi J, Lee C, Zhou M, Zhao S, Du Y.   +11 more
europepmc   +1 more source