Results 221 to 230 of about 149,082 (291)
Exploring Desmin as a Potential Modifier in Duchenne Muscular Dystrophy–Associated Cardiomyopathy
ABSTRACT Aim Duchenne muscular dystrophy (DMD), a rare X‐linked genetic disorder, is affecting skeletal and cardiac muscles due to the loss of the dystrophin protein. Modifier proteins, whose expression is altered in DMD patients, may influence disease progression.
Brice‐Emmanuel Guennec +12 more
wiley +1 more source
Retraction: The Polyherbal Wattana Formula Displays Anti-Amyloidogenic Properties by Increasing α-Secretase Activities. [PDF]
PLOS One Editors.
europepmc +1 more source
Temporal roles of collagen XII in regulating cell and matrix organization during tendon development were investigated by tendon‐targeted knockout throughout development and induced knockdown at birth. Tendon‐targeted knockout disrupted patellar tendon morphology, cell and matrix organization, and mechanical properties.
Ashley K. Fung +6 more
wiley +1 more source
USP10 inhibits the degradation of α-synuclein, a pathogenic factor associated with Parkinson's disease, by inhibiting chaperone-mediated autophagy. [PDF]
Anisimov S +6 more
europepmc +1 more source
ORM1 promotes LPS‐induced ARDS by activating NF‐κB in alveolar epithelial II cells, upregulating TF/PAI‐1 to cause hypercoagulation and fibrinolysis inhibition, leading to lung injury. ORM1 knockdown reverses these effects, indicating therapeutic potential.
Xianjun Chen +12 more
wiley +1 more source
MyD88 orchestrates fatty acid metabolism in tumor-associated macrophages and non-alcoholic fatty liver disease-related hepatocarcinogenesis. [PDF]
Chen H +7 more
europepmc +1 more source
Objective Autoimmunity occurs due to the tactics between pathogenic and regulatory factors in systemic organs. Although interorgan communication has been demonstrated in various diseases, the effects of the crosstalk between the immune system and other organs on autoimmune disease is unknown.
Kunihiro Otsuka +8 more
wiley +1 more source
The E3 ubiquitin ligase MARCH9 alleviates pyroptosis by regulating NLPR3 ubiquitination following myocardial ischemia reperfusion. [PDF]
Lu H +9 more
europepmc +1 more source

