Results 51 to 60 of about 2,181,379 (230)

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Constraining reionization using the thermal history of the baryons [PDF]

, 2000
The thermal evolution of the intergalactic medium (IGM) depends on the reionization history of the universe. Numerical simulations indicate that the low density IGM, which is responsible for the low column density Ly-alpha forest, follows a well defined ...
Efstathiou, G., J.Franco, L.Terlevich, O.López-Cruz, \& I.Aretxaga, Rauch, M., Sargent, W.L.W., Schaye, J., Theuns, T.   +6 more
core   +1 more source

Does Clade Density Constrain Geographical Range Evolution?

Ecology and Evolution
ABSTRACTThe role of biotic interactions, such as interspecific competition, in driving geographical range evolution is still poorly understood. For instance, lineages distributed across regions with a large number of potential competitors might experience some level of geographical packing of their range limits, so that changes in their geographical ...
Marcio R. Pie, Raquel Divieso, Fernanda S. Caron   +2 more
openaire   +4 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

The role and implications of mammalian cellular circadian entrainment

FEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

The Effect of Saturation on Belief Propagation Decoding of LDPC Codes

, 2014
We consider the effect of LLR saturation on belief propagation decoding of low-density parity-check codes. Saturation occurs universally in practice and is known to have a significant effect on error floor performance.
Iyengar, Aravind, Kudekar, Shrinivas, Richardson, Tom   +2 more
core   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

The density evolution of IRAS galaxies

The Astrophysical Journal, 1992
A maximum likelihood test for density evolution is applied to a full-sky redshift survey of 5297 galaxies selected from the IRAS data base and flux-limited at 1.2 Jy. No evidence for evolution is found. Attention is given to important systematic errors which decrease the certainty with which evolution can be measured, namely, limited knowledge of the ...
Karl B. Fisher, Michael A. Strauss, Marc Davis, Amos Yahil, John P. Huchra   +4 more
openaire   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source