Results 101 to 110 of about 1,778,097 (289)
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
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Assumptions about the dynamics sources and mechanisms of plate tectonic activities
Frontiers in Earth ScienceThe problem of the driving source and power mechanism of plate motion remains a major scientific issue in urgent need of resolution. Based on the isostatic hypothesis model proposed by G.B.
Ziyun Chen +4 more
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Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
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Molecular Oncology, EarlyView.Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor +2 more
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Journal of Extracellular VesiclesExtracellular vesicles (EVs) secreted by mammalian cells are highly heterogeneous in content and function. Whether this is also true for EVs secreted by plant cells is not yet known.
Benjamin L. Koch +5 more
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Zhongwai GongluTo reveal the effects of the number of dry-wet cycles and the material density gradient on the deterioration laws of macroscopic mechanical properties, microscopic damage mechanisms, and failure modes of foam concrete, foam concrete test blocks with ...
XU Ke, ZHANG Jun, KUANG Yuyang
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Generation of a controllable electron density gradient using a single plasma source
AIP Advances, 2019 In this work, an experimental design for generation of the controllable electron density gradient is achieved through a large area oxide coated cathode and two stainless meshes.
Yiming Ling +5 more
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Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
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Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
FEBS Open Bio, EarlyView.Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
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Terrestrial, Atmospheric and Oceanic Sciences, 2009 In this paper, a two-dimensional numerical study of a plasma density gradient effect on Farley-Buneman waves (FB waves) is per formed via a two-fluid code in which the electron inertia is neglected while the ion inertia is retained.
Chi-Lon Fern Fu-Shong Kuo
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