Results 121 to 130 of about 1,914,645 (291)
FLEXR: automated multi-conformer model building using electron-density map sampling. [PDF]
Stachowski TR, Fischer M.
europepmc +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Evaluating quantitative proton‐density‐mapping methods
AbstractQuantitative magnetic resonance imaging (qMRI) aims to quantify tissue parameters by eliminating instrumental bias. We describe qMRI theory, simulations, and software designed to estimate proton density (PD), the apparent local concentration of water protons in the living human brain.
Aviv, Mezer +4 more
openaire +3 more sources
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Protein Structure Predictions, Atomic Model Building, and Validation Using a Cryo-EM Density Map from Hepatitis B Virus Spherical Subviral Particle. [PDF]
DiNunno N, Bianchini EN, Liu H, Wang JC.
europepmc +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Identification of genetic loci conferring seed coat color based on a high-density map in soybean. [PDF]
Yuan B +9 more
europepmc +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
PGC-Net: A Novel Encoder-Decoder Network With Path Gradient Flow Control for Cell Counting
To carry out cell counting, it is common to use neural network models with an encoder-decoder structure to generate regression density maps. In the encoder-decoder structure, skip connections are usually used to retain detailed features.
Jianke Li +4 more
doaj +1 more source
Landslides density map of S. Miguel Island, Azores archipelago [PDF]
The Azores archipelago is located in the Atlantic Ocean and is composed of nine volcanic islands. S. Miguel, the largest one, is formed by three active, E-W trending, trachytic central volcanoes with caldera (Sete Cidades, Fogo and Furnas). Chains of
P. Valadão +3 more
doaj

