Results 11 to 20 of about 63,507 (333)
RETRACTED: Biomimetic supramolecular protein matrix restores structure and properties of human dental enamel [PDF]
Abstract The authors have requested that this preprint be removed from Research Square.
Álvaro Mata +23 more
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Storage conditions differentially alter the human tooth enamel proteome [PDF]
IntroductionExfoliated or extracted human teeth are increasingly used as accessible records of health history, biomarkers for predicting health risks, or analyzed for organic components to uncover the mechanisms of atypical development or disease. During
Hakan Karaaslan +2 more
doaj +2 more sources
Novel MMP20 (matrix metalloproteinase 20) mutations causing hypoplastic-hypomaturation amelogenesis imperfecta [PDF]
Background/purpose: Matrix metalloproteinase 20 (MMP20) is a proteinase essential for dental enamel formation. Mutations in human MMP20 cause autosomal recessive amelogenesis imperfecta (AI), characterized by thin and soft enamel.
Shih-Kai Wang +7 more
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Matrix metalloproteinase-20 mediates dental enamel biomineralization by preventing protein occlusion inside apatite crystals [PDF]
Reconstruction of enamel-like materials is a central topic of research in dentistry and material sciences. The importance of precise proteolytic mechanisms in amelogenesis to form a hard tissue with more than 95% mineral content has already been reported. A mutation in the Matrix Metalloproteinase-20 (MMP-20) gene results in hypomineralized enamel that
Saumya Prajapati +4 more
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Amelogenesis, beginning with thickened epithelial aggregation and ending with highly mineralized enamel formation, is a process mediated by a complex signaling network that involves several molecules, including growth and transcription factors. During early tooth development, the transcription factor B‑cell CLL/lymphoma 11B (Bcl11b) participates in ...
Ziyue Li +4 more
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Enamel and dental anomalies in latent‐transforming growth factor beta‐binding protein 3 mutant mice [PDF]
Latent‐transforming growth factor beta‐binding protein 3 (LTBP‐3) is important for craniofacial morphogenesis and hard tissue mineralization, as it is essential for activation of transforming growth factor‐β (TGF‐β). To investigate the role of LTBP‐3 in tooth formation we performed micro‐computed tomography (micro‐CT), histology, and scanning electron ...
Supawich Morkmued +8 more
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Abundant Calcium Homeostasis Machinery in Rat Dental Enamel Cells [PDF]
Enamel cells handle large amounts of calcium, particularly during the developmental phase (termed maturation) when dental enamel is hypermineralized. The extent of intracellular calcium burden, and the nature of calcium homeostasis machinery used to accommodate it, are largely unknown. Here, the calcium‐binding capacity of enamel cell cytosol was found
Michael J. Hubbard
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The aim of this study was to determine the bone regenerative potential of enamel matrix derivative (EMD) in a defect around a dental implant.Five mongrel dogs were used. A circumferential defect was created around osteotomies that had been fabricated to receive titanium implants.
Hyun‐Chang Lim +3 more
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Background: Dental development, together with regenerative dentistry, depends heavily on three main enamel matrix proteins, including amelogenin, enamelin, and ameloblastin.
Kahaf Mujtaba +5 more
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Expression of Enamel Proteins in Rough Endoplasmic Reticulum and Golgi Complex in Human Dental Germs [PDF]
Tooth enamel is the hardest tissue in the body. The organic matrix configuration is provided by the main proteins amelogenin, ameloblastin and enamelysin (MMP20), an enzyme that helps to shape the matrix. The aim of this study was to determine by histochemistry the expression of amelogenin and enamelysin through the rough endoplasmic reticulum in the ...
Francisco Javier Gutiérrez-Cantú +8 more
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