Results 1 to 10 of about 19,068 (302)

Effect of melatonin on human dental papilla cells. [PDF]

Int J Mol Sci, 2014
Melatonin regulates a variety of biological processes, which are the control of circadian rhythms, regulation of seasonal reproductive function and body temperature, free radical scavenging and so on. Our previous studies have shown that various cells exist in human and mouse tooth germs that express the melatonin 1a receptor (Mel1aR).
Tachibana R, Tatehara S, Kumasaka S, Tokuyama R, Satomura K.   +4 more
europepmc   +6 more sources

C-Jun N-terminal kinase (JNK) pathway activation is essential for dental papilla cells polarization. [PDF]

PLoS ONE, 2021
During tooth development, dental papilla cells differentiate into odontoblasts with polarized morphology and cell function. Our previous study indicated that the C-Jun N-terminal kinase (JNK) pathway regulates human dental papilla cell adhesion ...
Jiao Luo, Xiujun Tan, Ling Ye, Chenglin Wang   +3 more
doaj   +2 more sources

Piezo1 Regulates Odontogenesis via a FAM83G-Mediated Mechanism in Dental Papilla Cells In Vitro and In Vivo [PDF]

Biomolecules
This study explored the role of Piezo1 in the odontogenic differentiation of dental papilla cells (DPCs) and tissue, focusing on a mechanism involving family with sequence similarity 83, member G (FAM83G). Here, we found Piezo1, a mechanosensitive cation
Xinyue Sheng, Jingzhou Li, Haozhen Ma, Hongwen He, Qin Liu, Shilin Jia, Fuping Zhang, Fang Huang   +7 more
doaj   +2 more sources

Unraveling the Role of the Apical Papilla During Dental Root Maturation

Frontiers in Cell and Developmental Biology, 2021
The apical papilla is a stem cell rich tissue located at the base of the developing dental root and is responsible for the progressive elongation and maturation of the root.
Ronald B. Driesen, Pascal Gervois, Tim Vangansewinkel, Ivo Lambrichts   +3 more
doaj   +3 more sources

Influence of inter-proximal dimensions on inter-dental papilla presence. [PDF]

Bioinformation
The presence of interdental papilla in relation to vertical distance between alveolar crest and the contact point, as well as horizontal distance between adjacent roots is of interest to dentists. Hence, 50 patients with a total of 501-papilla were examined.
Desai J, Vishnoi S, P Nadig P, Raj K, Kasundra D, Bharucha D.   +5 more
europepmc   +3 more sources

Decoding dental mesenchymal stem cells diversity: single-cell transcriptomics maps heterogeneity in molar development [PDF]

Frontiers in Cell and Developmental Biology
The spatial and temporal differences influence the development of vertebrate teeth in specific cell types, as well as the precise regulation of signalling networks.
Ruilin Zhang, Ruilin Zhang, Ruilin Zhang, Ruilin Zhang, Leyi Chen, Leyi Chen, Wanli Xu, Wanli Xu, Wenan Xu, Wenan Xu, Buling Wu, Buling Wu   +11 more
doaj   +2 more sources

Histatin-1 promotes the expression of markers associated with odontoblastic differentiation in the dental pulp and apical papilla [PDF]

Scientific Reports
Complex tooth injuries, including dental caries, require the reestablishment of tissue architecture and functionality through the regeneration of cellular populations that enable tertiary dentin formation and the reestablishment of vascular and neural ...
Patricio Silva, Mauricio Garrido, Héctor A. Tapia, Diego Ormeño, Sebastián Benito, Jorge Segura, Floris J. Bikker, Kamran Nazmi, Elías Utreras, Mónica Cáceres, Vicente A. Torres   +10 more
doaj   +2 more sources

SMAD7 regulates the canonical Wnt signaling through TGF-β cascade crosstalk and SMAD7/β-CATENIN transcription factor complex formation during tooth regeneration [PDF]

International Journal of Oral Science
Tooth morphogenesis is orchestrated by a complex interplay of signaling pathways and transcription factors that control cell proliferation, apoptosis, and differentiation, with the Wnt/β-catenin signaling pathway playing a pivotal role.
Qiuyu Chen, Zhi Liu, Bohuai Zhou, Cheng Liang, Yiping Chen, Weidong Tian, Tian Chen   +6 more
doaj   +2 more sources

Impact of Conventional vs. Vertical Tooth Extraction on Three-Dimensional Soft Tissue Remodelling and Aesthetic Parameters of Adjacent Teeth: One-Year Results of a Randomized Clinical Trial [PDF]

Dentistry Journal
Objectives: Post-extraction remodelling of hard and soft tissues results in volume reduction, leading to aesthetic challenges in planning prosthetic restorations, particularly in the anterior maxilla.
Jonas Kopp, Ragai Edward Matta, Mayte Buchbender, Werner Adler, Marco Kesting, Manfred Wichmann, Anna Seidel   +6 more
doaj   +2 more sources

Evaluation of the Effect of Hyaluronic Acid Injection on the Reconstruction of Reduced Interdental Papillae in Patients Referred to Shiraz School of Dentistry [PDF]

Journal of Dentistry, 2023
Statement of the Problem: The occurrence of papillary defects adjacent to teeth or dental implants causes both the dental staff and the patients to be concerned about the esthetic issues.
Reihaneh Ebrahimi, Hooman Khorshidi, Rabieh Boroumand, Ali Azadikhah, Pardis Haddadi   +4 more
doaj   +1 more source