Results 241 to 250 of about 5,484,719 (297)

Accuracy of surrogate outcomes in predicting true endpoints of surgical periodontal therapy. A narrative review with a 20‐year longitudinal analysis

Periodontology 2000, EarlyView.
Abstract Background Periodontal clinical trials commonly use surrogate end points (e.g., probing pocket depth [PPD], clinical attachment level [CAL], bleeding on probing [BoP], and composite scores such as the Periodontal Risk Score [PRS]) for efficiency, yet tooth loss, treatment burden/cost, and re‐treatment are the definitive patient‐relevant ...
Muhammad H. A. Saleh, Abdusalam E. Alrmali, Fatemeh SamavatiJame, Hamzeh Almanshi, Shahad Alhazmi, Sawsan Abu‐Reyal, Hom‐Lay Wang, Ann Decker   +7 more
wiley   +1 more source

Effects of Thai propolis mixed in mineral trioxide aggregate on matrix metalloproteinase-2 expression and activity in inflamed human dental pulp cells. [PDF]

J Appl Oral Sci
Tiyapitsanupaisan N, Kantrong N, Puasiri S, Makeudom A, Krisanaprakornkit S, Chailertvanitkul P.   +5 more
europepmc   +1 more source

Understanding exosomes in regenerative dentistry

Periodontology 2000, EarlyView.
Abstract Background Regenerative dentistry is shifting from cell‐based strategies to cell‐free biologics capable of orchestrating intricate tissue repair. Exosomes, nanosized extracellular vesicles carrying bioactive molecular payloads, have emerged as central modulators of intercellular communication.
Paras Ahmad, Anton Sculean, Richard J. Miron   +2 more
wiley   +1 more source

Impaired Tertiary Dentin Secretion after Shallow Injury in Tgfbr2-Deficient Dental Pulp Cells Is Rescued by Extended CGRP Signaling. [PDF]

Int J Mol Sci
Stanwick M, Fenesha F, Hamid A, Kang K, Kanniard D, Kim I, Mandarano N, Schumacher FL, Peters SB.   +8 more
europepmc   +1 more source

Understanding extracellular vesicle biology, isolation, and characterization: The theory of EV‐erything

Periodontology 2000, EarlyView.
Abstract Background Extracellular vesicles (EVs), especially exosomes, are nanoparticles increasingly recognized as key regulators of intercellular communication in both physiological and pathological aspects. Despite rapid progress, inconsistencies in nomenclature, isolation, and characterization continue to restrict translational advancement.
Paras Ahmad, Nima Farshidfar, Nathan E. Estrin, Yulan Wang, Yufeng Zhang, Anton Sculean, Richard J. Miron   +6 more
wiley   +1 more source

MicroRNA-27a-5p Downregulates Expression of Proinflammatory Cytokines in Lipopolysaccharide-Stimulated Human Dental Pulp Cells via the NF-κB Signaling Pathway. [PDF]

Int J Mol Sci
Wang S, Kawashima N, Han P, Sunada-Nara K, Yu Z, Tazawa K, Fujii M, Kieu TQ, Okiji T.   +8 more
europepmc   +1 more source

Periodontitis and metabolic dysfunction‐associated steatotic liver disease

Periodontology 2000, EarlyView.
Abstract Objective Periodontitis is a chronic inflammatory disease with systemic effects that extend beyond the oral cavity and contribute to systemic immune and metabolic dysregulation. Chronic liver diseases, particularly metabolic dysfunction‐associated steatotic liver disease (MASLD) and its progressive phenotypes, have emerged as major global ...
Rafael Scaf de Molon, Erica Dorigatti de Avila, Davi da Silva Barbirato, Mariana Fampa Fogacci, Jamil Awad Shibli, Anton Sculean, Alpdogan Kantarci   +6 more
wiley   +1 more source

Exploring the Therapeutic Potential of Extracellular Vesicles Derived from Human Immature Dental Pulp Cells on Papillary Thyroid Cancer. [PDF]

Int J Mol Sci
Teixeira MR, Alievi AL, da Costa VR, Kerkis I, Araldi RP.   +4 more
europepmc   +1 more source

Oral health and systemic health outcomes: A call for interdisciplinary action

Periodontology 2000, EarlyView.
Abstract Objectives To make the case, from periodontology and dental public health, for interdisciplinary action on oral and systemic health, and to set out recommendations for practice, policy, education, and research. Materials and Methods A joint working group of the European Federation of Periodontology (EFP) and the European Association of Dental ...
Moritz Kebschull, Ryan T. Demmer, Nigel Pitts, Huda Yusuf, Gitana Rederiene, Nikolaos Donos, Wim Teughels, Raman Bedi, Orsolya Nemeth, Mia Rakic, Stéphanie Tubert‐Jeannin, Raimondo Ascione, Francesco D'Aiuto, James Deschner, Thomas Dietrich, Mili Doshi, Julian Fisher, Ramón Juanatey, Phoebus Madianos, Katalin Nagy, Barry Quinn, Saulė Skinkytė, Lina Stangvaltaite‐Mouhat, Maria van den Muijsenbergh, Josep Vilaseca, Nicola West, Anton Sculean, Andreas Stavropoulos, Kenneth Eaton, Joint EFP/EADPH Working Group   +29 more
wiley   +1 more source

Histiocytes: Multifaceted Regulators of Health and Disease

Veterinary Clinical Pathology, EarlyView.
ABSTRACT The mononuclear phagocyte system encompasses macrophages, dendritic cells (DCs), and monocytes. Tissue‐resident macrophages and dendritic cells arise during embryogenesis and are replenished either through self‐renewal or by monocytes during inflammation.
Erika J. Gruber
wiley   +1 more source