Abstract Tumor necrosis factor-alpha (TNF-α) is a cytokine involved in the immune-inflammatory response. It can induce an odontoblastic phenotype and enhance biomineralization in dental pulp mesenchymal stem cells but does not have the same effect on osteoblasts. The reasons for this differential response, despite the shared lineage of these cell types,
Giuliana de Campos Chaves LAMARQUE +7 more
openaire +1 more source
Mesenchymal stem cells derived from inflamed dental pulpal and gingival tissue: a potential application for bone formation [PDF]
Background: Chronic periodontal disease is an infectious disease consisting of prolonged inflammation of the supporting tooth tissue and resulting in bone loss.
Campisi, G. +7 more
core +1 more source
ABSTRACT This in vitro study evaluated the effects of intracanal medications on the metabolic activity and adhesion of human periodontal ligament‐derived mesenchymal stem cells. Tested groups included Control (without medication), Triple Antibiotic Paste (TAP), Double Antibiotic Paste (DAP), calcium hydroxide with saline, calcium hydroxide with 2 ...
Arian Braido +7 more
wiley +1 more source
Pulpitis is a common inflammatory oral disease that can lead to pulp necrosis. The aim of this study is to investigate the expression and regulatory mechanisms of ATF3, a potential therapeutic marker, in pulpitis.
Liu Liu +4 more
doaj +1 more source
Interplay between dental pulp tissue osteoprotegerin and TNF-α levels with micromorphological changes in the teeth of patients with chronic pulpitis [PDF]
Background/Aim. Chronic pulpitis (CP) is an inflammatory dental pulp disorder associated with various pathophysiological mechanisms in its origin. The aim of the study was to evaluate the changes in the pulp tissue of osteoprotegerin (OPG) and tumor ...
Šubarić Ljiljana B. +9 more
doaj +1 more source
Consensus-Based Recommendations on Pulp Therapies in Primary and Permanent Teeth: IAPD Porto Forum. [PDF]
ABSTRACT Background Recent understanding of pulp biology has shifted treatment paradigms toward preservation‐based approaches. Traditional diagnostic terminology and treatment protocols require updating to align with current evidence supporting the pulp's healing capacity.
Dhar V +15 more
europepmc +2 more sources
Cyotoxicity of Etidronate as an Endodontic Chelator Against Periodontal Ligament Fibroblast
ABSTRACT Etidronic acid (HEBP) causes fewer alterations in dentine and can be used mixed with sodium hypochlorite during root canal preparation. This study investigated the cytotoxicity effects of the HEDP and EDTA on human periodontal ligament fibroblast cells. Primary culture was established from human periodontal ligament tissue of one donor and was
Bruno Vila Nova de Almeida +6 more
wiley +1 more source
Revascularization of an Immature Maxillary First Premolar with Necrotic Tissue: A Case Report
Objectives The purpose of this study was to present a case of regenerative endodontic procedure. Case The maxillary 1st premolar of a 9-year-old patient was diagnosed as necrotic.
Behnam Rahbani Nobar +3 more
doaj +1 more source
Clinical Applicability of Stem Cell Therapy in Dental Diseases: A Systematic Review of Available Clinical Trials [PDF]
Background: Developing cell-based therapeutic methods for differentiating various stem cells into dental tissues could be a revolutionary step toward using cell therapy for dental diseases.
Atena Shiva +5 more
doaj
In vitro study of the pulp chamber temperature rise during light-activated bleaching [PDF]
This study evaluated in vitro the pulp chamber temperature rise induced by the light-activated dental bleaching technique using different light sources.
CARRASCO, Thaise Graciele +2 more
core +3 more sources

