Results 91 to 100 of about 12,770 (234)

Histopathological Assessment of Tricalcium Aluminate-free Mineral Trioxide Aggregate and Two Antibacterial Enhanced Mineral Trioxide Aggregates As Pulpotomy Agents in Rat Model

European Endodontic Journal
Objective: To evaluate the effect of a newly developed MTA-based material and two antibacterial-enhanced MTAs as pulp capping materials in immature permanent dental elements underwent full pulpotomy.
Harsh Baldawa, Vignesh Ravindran, Ganesh Jeevanandan, Abirami Arthanari, Kavalipurapu Venkata Teja, Gianrico Spagnuolo, Carlo Rengo, Flavia Iaculli, Mariangela Cernera   +8 more
doaj   +1 more source

Inflammation‐Regeneration Axis of Dental Pulp Stem Cells: Wnt/NF‐κB Crosstalk

International Endodontic Journal, EarlyView.
ABSTRACT Background Inflammation critically determines dental pulp regenerative outcomes, with dental pulp stem cells (DPSCs) orchestrating tissue homeostasis through differentiation, self‐renewal and immunomodulation processes dynamically regulated by Wnt/β‐catenin and NF‐κB signaling crosstalk.
V. Rajasekar, M. Huang, M. M. Abdalla, P. Neelakantan, C. K. Y. Yiu   +4 more
wiley   +1 more source

Mamba‐Based Deep Learning Model for Automated Periapical Index Classification Using Periapical Radiographs and Clinical Metadata

International Endodontic Journal, EarlyView.
ABSTRACT Aim Apical periodontitis (AP) diagnosis primarily relies on periapical radiographs (PRs) and the Periapical Index (PAI) scoring system. However, existing automated approaches often simplify PAI into binary categories or ignore essential clinical metadata, limiting diagnostic performance and applicability.
Jiyun Lee, Yudam Park, Sunil Kim, Ikbeom Jang   +3 more
wiley   +1 more source

The Survival and Success of Teeth With External Cervical Resorption: A Multi‐Centre, Retrospective Study

International Endodontic Journal, EarlyView.
ABSTRACT Objectives To evaluate the survival and success outcomes of teeth affected by external cervical resorption (ECR) managed using three distinct treatment strategies, with periapical radiographs and small field of view cone beam computed tomography used for diagnosis and treatment planning.
Shanon Patel, Ryan Walsh, Paula Villa, Brent Hiebert, Elizabeth Shin Perry, Rahul Sadhwani, Nassr Al‐Nuaimi   +6 more
wiley   +1 more source

Outcomes of Root Canal Treatment in Patients With Autoimmune Disease: A Retrospective Case–Control Study

International Endodontic Journal, EarlyView.
ABSTRACT Aim The purpose of this study was to compare the outcome of nonsurgical root canal treatment (RCT) in patients with autoimmune diseases (AD) with the outcome in patients without AD. The null hypothesis was: there is no difference in the outcomes of RCT regardless of the patient group. Results were also compared among AD subgroups: inflammatory
Seoyeon Lee, Euiseong Kim, Hoiin Jung, Hyejin Kim, Sunil Kim   +4 more
wiley   +1 more source

Regenerative Endodontics in Teeth With Irreversible Pulpitis: A Scoping Review

International Endodontic Journal, EarlyView.
ABSTRACT Introduction Regenerative endodontic procedures (REPs) have been widely used to manage a range of pulpal pathologies, particularly in immature permanent teeth. The development of bioactive calcium silicate–based materials has led to a paradigm shift in vital pulp therapy (VPT) and REPs.
Mahmoud Torabinejad, Neda Najafimakhsoos, George Bogen   +2 more
wiley   +1 more source

Lipopolysaccharide-induced dental pulp cell apoptosis and the expression of Bax and Bcl-2 in vitro

Brazilian Journal of Medical and Biological Research, 2010
Lipopolysaccharide exerts many effects on many cell lines, including cytokine secretion, and cell apoptosis and necrosis. We investigated the in vitro effects of lipopolysaccharide on apoptosis of cultured human dental pulp cells and the expression of ...
H. Yang, Y.T. Zhu, R. Cheng, M.Y. Shao, Z.S. Fu, L. Cheng, F.M. Wang, T. Hu   +7 more
doaj  

Association Between the Root Canal Microbiome and Apical Lesion Size: An Observational Shotgun Metagenomic Study

International Endodontic Journal, EarlyView.
ABSTRACT Aim The aim was to characterize the taxonomic and functional composition of the microbiome involved in primary endodontic infections and to evaluate their association with the periapical lesion size using shotgun metagenomic sequencing. Methodology Samples from primary root canal infections diagnosed with apical periodontitis were analysed ...
Virginia Pérez‐Carrasco, David Uroz‐Torres, Ana Soriano‐Lerma, Miguel Soriano, Jose Antonio García‐Salcedo, Maria Teresa Arias‐Moliz   +5 more
wiley   +1 more source

Polydatin Modulates Inflammatory Cytokine Expression in Lipoteichoic Acid-Stimulated Human Dental-Pulp Stem Cells

Journal of Functional Biomaterials
Gram-positive bacteria are responsible for initiating dental caries. In this process, lipoteichoic acid (LTA), which is expressed on Gram-positive bacteria cell walls, binds to the dental pulp cells, triggering an immune response, followed by ...
Rawan Al-Ateeq, Mona Elsafadi, Manikandan Muthurangan, Solaiman Al-Hadlaq   +3 more
doaj   +1 more source

The Role of Neuropeptide Y in Dental Pulp: Balancing Neurogenic Inflammation and Pain Modulation

International Endodontic Journal, EarlyView.
ABSTRACT Background Dental pulp is a densely innervated, low‐compliance tissue in which neurogenic inflammation can rapidly escalate into oedema, raised intrapulpal pressure, microvascular compromise, and pain. While Substance P (SP) and Calcitonin gene‐related peptide (CGRP) are well‐established drivers of pulp vasodilation, the Neuroopeptide Y (NPY ...
Javier Caviedes‐Bucheli, Esteban Ulate, Hugo‐Roberto Munoz, Nestor Ríos‐Osorio   +3 more
wiley   +1 more source