Abstract Aim Establishing functional circulation on time is crucial to dental pulp tissue regeneration. Mesenchymal stem cells (MSCs) could act as mural cells to stabilize newly formed blood vessels, accelerating anastomosis. Our preliminary study found that direct coculture of dental pulp stem cells (DPSCs) and human umbilical vein endothelial cells ...
Jialin Zhong+8 more
wiley +1 more source
Investigating the Effects of Conditioned Media from Stem Cells of Human Exfoliated Deciduous Teeth on Dental Pulp Stem Cells [PDF]
Pulp regeneration has recently attracted interest in modern dentistry. However, the success ratio of pulp regeneration is low due to the compromising potential of stem cells, such as their survival, migration, and odontoblastic differentiation.
Dashnyam, Khandmaa+11 more
core
Adult Human Dental Pulp Stem Cells Differentiate Toward Functionally Active Neurons Under Appropriate Environmental Cues [PDF]
Agnieszka Arthur+4 more
openalex +1 more source
Abstract Aim Recent findings suggest that mitigating ferroptosis could serve as an effective strategy for treating inflammation. This study aimed to investigate the role that the enhancer of zeste homologue 2 (EZH2) mediated the signal transducer and activator of transcription 3 (stat3) methylation plays in the modulation of ferroptosis in pulpitis ...
Weilin Zhou+8 more
wiley +1 more source
Theory of Robustness of Irreversible Differentiation in a Stem Cell System: Chaos hypothesis [PDF]
Based on extensive study of a dynamical systems model of the development of a cell society, a novel theory for stem cell differentiation and its regulation is proposed as the ``chaos hypothesis''. Two fundamental features of stem cell systems - stochastic differentiation of stem cells and the robustness of a system due to regulation of this ...
arxiv
Collection, Cryopreservation, and Characterization of Human Dental Pulp–Derived Mesenchymal Stem Cells for Banking and Clinical Use [PDF]
Brandon C. Perry+8 more
openalex +1 more source
Abstract Background Solubilized endogenous dentine extracellular matrix components (dECMs) are potent mediators in pulp regeneration and could potentially promote similar healing effects in diseased periradicular tissues by upregulating local mesenchymal stem cell‐derived regenerative events.
Satnam Singh Virdee+4 more
wiley +1 more source
Successful isolation, in vitro expansion and characterization of stem cells from Human Dental Pulp
BACKGROUND: Recent studies have shown that mesenchymal stem cells isolated from post natal human dental pulp, (Dental pulp stem cells-DPSCs) which is from permanent teeth and SHED (stem cells from human exfoliated deciduous teeth),the Periodontal ...
Preethy SP+12 more
doaj
Effect of light‐cured pulp capping materials on human dental pulp cells in vitro
Abstract Aim Gold standard as material in vital pulp therapy (VPT) is hydraulic calcium silicate cements (HCSC). To circumvent their prolonged setting time, light‐cured pulp capping materials containing calcium silicate or calcium hydroxide powder are available.
Laurentia Schuster+3 more
wiley +1 more source
The potential therapeutic roles of dental pulp stem cells in spinal cord injury
Spinal cord injury (SCI) can lead to serious functional disorders, which have serious impacts on patients and society. The current traditional treatments of SCI are not effective the injured spinal cord is difficult to repair and regenerate.
Jing Fu+10 more
doaj +1 more source