Dental Pulp Stem Cells and Current in vivo Approaches to Study Dental Pulp Stem Cells in Pulp Injury and Regeneration [PDF]
Dental pulp stem cells (DPSCs) have garnered significant interest in dental research for their unique characteristics and potential in tooth development and regeneration. While there were many studies to define their stem cell-like characteristics and osteogenic differentiation functions that are considered ideal candidates for regenerating damaged ...
Dongwook Yang+2 more
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The treatment of bone defects by stem cells (MSCs) has achieved limited success over the recent few decades. The emergence of exosomes provides a new strategy for bone regeneration.
Jia Guo+9 more
semanticscholar +2 more sources
Atlas of human dental pulp cells at multiple spatial and temporal levels based on single-cell sequencing analysis [PDF]
The dental pulp plays a crucial role in the long-term maintenance of tooth function. The progress of endodontic treatment and pulp tissue regeneration engineering has made pulp-regeneration therapy promising in clinical practice.
Huihui Ren+4 more
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Extracellular matrix of dental pulp stem cells: Applications in pulp tissue engineering using somatic MSCs [PDF]
Dental Caries affects approximately 90% of the world’s population. At present, the clinical treatment for dental caries is root canal therapy. This treatment results in loss of tooth sensitivity and vitality.
Sriram eRavindran+2 more
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Application of thermosensitive-hydrogel combined with dental pulp stem cells on the injured fallopian tube mucosa in an animal model [PDF]
Objectives: Fallopian tube (FT) injury is an important factor that can lead to tubal infertility. Stem-cell-based therapy shows great potential for the treatment of injured fallopian tube.
Lihua Luo+9 more
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Evaluating the efficacy of human dental pulp stem cells and scaffold combination for bone regeneration in animal models: a systematic review and meta-analysis [PDF]
Introduction Human adult dental pulp stem cells (hDPSC) and stem cells from human exfoliated deciduous teeth (SHED) hold promise in bone regeneration for their easy accessibility, high proliferation rate, self-renewal and osteogenic differentiation ...
Amin Namjoynik+2 more
semanticscholar +7 more sources
Biomimetic Extracellular Matrix Mediated Somatic Stem Cell Differentiation: Applications in Dental Pulp Tissue Regeneration. [PDF]
Dental caries is one of the most widely prevalent infectious diseases in the world. It affects more than half of the world’s population. The current treatment for necrotic dental pulp tissue arising from dental caries is root canal therapy.
Sriram eRavindran, ANNE eGEORGE
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Dental pulp polyps contain stem cells comparable to the normal dental pulps [PDF]
Few studies investigated the isolation of stem cells from pathologically injured dental tissues. The aim of this study was to assess the possibility of isolation of stem cells from pulp polyps (chronic hyperplastic pulpitis), a pathological tissue produced in an inflammatory proliferative response within a tooth.Pulp polyp tissues were enzymatically ...
Attar, Armin+7 more
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The effects of ageing on dental pulp stem cells, the tooth longevity elixir [PDF]
Stem cells are essential for tissue homeostasis and regeneration throughout the lifespan of multicellular rganisms. The decline in stem cell function during advanced age is associated with a reduced regenerative potential of tissues that leads to an ...
I Iezzi+3 more
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The Angiogenic Potential of DPSCs and SCAPs in an In Vivo Model of Dental Pulp Regeneration [PDF]
Adequate vascularization, a restricting factor for the survival of engineered tissues, is often promoted by the addition of stem cells or the appropriate angiogenic growth factors.
Petra Hilkens+5 more
doaj +6 more sources