Results 31 to 40 of about 6,028,836 (265)

Vascularization of a Bone Organoid Using Dental Pulp Stem Cells

open access: yesStem Cells International, 2023
Bone organoids offer a novel path for the reconstruction and repair of bone defects. We previously fabricated scaffold-free bone organoids using cell constructs comprising only bone marrow-derived mesenchymal stem cells (BMSCs). However, the cells in the
Ao-Nan Li   +5 more
semanticscholar   +1 more source

Anti-inflammatory effect of dental pulp stem cells

open access: yesFrontiers in Immunology, 2023
Dental pulp stem cells (DPSCs) have received a lot of attention as a regenerative medicine tool with strong immunomodulatory capabilities. The excessive inflammatory response involves a variety of immune cells, cytokines, and has a considerable impact on
Fenyao Li   +5 more
semanticscholar   +1 more source

Conditioned medium from human dental pulp stem cells treats spinal cord injury by inhibiting microglial pyroptosis

open access: yesNeural Regeneration Research, 2023
Human dental pulp stem cell transplantation has been shown to be an effective therapeutic strategy for spinal cord injury. However, whether the human dental pulp stem cell secretome can contribute to functional recovery after spinal cord injury remains ...
Tao Liu   +10 more
semanticscholar   +1 more source

The effects of ageing on dental pulp stem cells, the tooth longevity elixir [PDF]

open access: yesEuropean Cells & Materials, 2019
Stem cells are essential for tissue homeostasis and regeneration throughout the lifespan of multicellular rganisms. The decline in stem cell function during advanced age is associated with a reduced regenerative potential of tissues that leads to an ...
I Iezzi   +3 more
doaj   +1 more source

The Migration and the Fate of Dental Pulp Stem Cells

open access: yesBiology, 2023
Simple Summary The importance of stem cells for regenerative medicine has grown significantly in recent years. This is because stem cells can differentiate into multiple cell types and are often easy to recover.
N. Lampiasi
semanticscholar   +1 more source

Exosome‐shuttled mitochondrial transcription factor A mRNA promotes the osteogenesis of dental pulp stem cells through mitochondrial oxidative phosphorylation activation

open access: yesCell Proliferation, 2022
The treatment of bone defects by stem cells (MSCs) has achieved limited success over the recent few decades. The emergence of exosomes provides a new strategy for bone regeneration.
Jia Guo   +9 more
semanticscholar   +1 more source

Discovering the Potential of Dental Pulp Stem Cells for Corneal Endothelial Cell Production: A Proof of Concept

open access: yesFrontiers in Bioengineering and Biotechnology, 2021
Failure of corneal endothelium cell monolayer is the main cause leading to corneal transplantation. Autologous cell-based therapies are required to reconstruct in vitro the cell monolayer.
Begoña M. Bosch   +5 more
doaj   +1 more source

Application of dental pulp stem cells in oral maxillofacial tissue engineering

open access: yesInternational Journal of Medical Sciences, 2022
In the maxillofacial area, soft and hard tissue abnormalities are caused by trauma, tumors, infection, and other causes that expose the maxillofacial region to the surface of the human body.
P. Liu   +7 more
semanticscholar   +1 more source

Exosomes Derived from Dental Pulp Stem Cells Show Different Angiogenic and Osteogenic Properties in Relation to the Age of the Donor

open access: yesPharmaceutics, 2022
Craniofacial tissue reconstruction still represents a challenge in regenerative medicine. Mesenchymal stem cell (MSC)-based tissue engineering strategies have been introduced to enhance bone tissue repair.
G. Brunello   +11 more
semanticscholar   +1 more source

Distal C terminus of CaV1.2 channels plays a crucial role in the neural differentiation of dental pulp stem cells. [PDF]

open access: yesPLoS ONE, 2013
L-type voltage-dependent CaV1.2 channels play an important role in the maintenance of intracellular calcium homeostasis, and influence multiple cellular processes.
Jianping Ge   +6 more
doaj   +1 more source

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