Results 51 to 60 of about 6,028,836 (265)

Biological characteristics of dental pulp stem cells and their potential use in regenerative medicine.

Journal of Oral Biosciences, 2022
BACKGROUND Regenerative medicine has emerged as a multidisciplinary field with the promising potential of renewing tissues and organs. The main types of adult stem cells used in clinical trials are hematopoietic and mesenchymal stem cells (MSCs).
M. Honda, H. Ohshima
semanticscholar   +1 more source

Extracellular matrix of dental pulp stem cells: Applications in pulp tissue engineering using somatic MSCs

Frontiers in Physiology, 2014
Dental Caries affects approximately 90% of the world’s population. At present, the clinical treatment for dental caries is root canal therapy. This treatment results in loss of tooth sensitivity and vitality.
Sriram eRavindran, Chun-Chieh eHuang, ANNE eGEORGE   +2 more
doaj   +1 more source

Dental Pulp Stem Cells: Advances to Applications

Stem Cells and Cloning : Advances and Applications, 2020
Dental pulp stem cells (DPSCs) have a high capacity for differentiation and the ability to regenerate a dentin/pulp-like complex. Numerous studies have provided evidence of DPSCs’ differentiation capacity, such as in neurogenesis, adipogenesis ...
T. W. Tsutsui
semanticscholar   +1 more source

Secreted factors from dental pulp stem cells improve Sjögren’s syndrome via regulatory T cell-mediated immunosuppression

Stem cell research & therapeutics, 2021
Background Sjögren’s syndrome (SS) is a chronic autoimmune disease primarily characterized by inflammation in the salivary and lacrimal glands. Activated T cells contribute to disease pathogenesis by producing proinflammatory cytokines, which leads to a ...
Mayu Matsumura-Kawashima, Kenichi Ogata, M. Moriyama, Yuka Murakami, Tatsuya Kawado, Seiji Nakamura   +5 more
semanticscholar   +1 more source

Periodontitis‐compromised dental pulp stem cells secrete extracellular vesicles carrying miRNA‐378a promote local angiogenesis by targeting Sufu to activate the Hedgehog/Gli1 signalling

Cell Proliferation, 2021
Previously, our investigations demonstrated robust pro‐angiogenic potentials of extracellular vesicles secreted by periodontitis‐compromised dental pulp stem cells (P‐EVs) when compared to those from healthy DPSCs (H‐EVs), but the underlying mechanism ...
Huan Zhou, Xuan Li, Rui-Xin Wu, Xiao-Tao He, Ying An, Xin-Yue Xu, Hai-Hua Sun, Li-An Wu, Fa-Ming Chen   +8 more
semanticscholar   +1 more source

Stem Cells from Human Exfoliated Deciduous Teeth (SHEDs) and Dental Pulp Stem Cells (DPSCs) Display a Similar Profile with Pericytes [PDF]

, 2021
Background: Pericytes play an important role in forming functional blood vessels and establishing stable and effective microcirculation, which is crucial for vascular tissue engineering.
ZHU, SY, Liu, H, Wong, HM, Wang, PL, Gu, M, Yang, YQ, Yuan, CY, Zhang, CF, Lin, YF   +8 more
core   +1 more source

Biomimetic Extracellular Matrix Mediated Somatic Stem Cell Differentiation: Applications in Dental Pulp Tissue Regeneration.

Frontiers in Physiology, 2015
Dental caries is one of the most widely prevalent infectious diseases in the world. It affects more than half of the world’s population. The current treatment for necrotic dental pulp tissue arising from dental caries is root canal therapy.
Sriram eRavindran, ANNE eGEORGE
doaj   +1 more source

Application of bioactive hydrogels combined with dental pulp stem cells for the repair of large gap peripheral nerve injuries

Bioactive Materials, 2020
Due to the limitations in autogenous nerve grafting or Schwann cell transplantation, large gap peripheral nerve injuries require a bridging strategy supported by nerve conduit. Cell based therapies provide a novel treatment for peripheral nerve injuries.
Lihua Luo, Yan He, Ling Jin, Yanni Zhang, F. Guastaldi, A. Albashari, Fengting Hu, Xiao-Yan Wang, Lei Wang, Jian Xiao, Ling-Li Li, Jianming Wang, A. Higuchi, Qingsong Ye   +13 more
semanticscholar   +1 more source

Identification of Dental Stem Cells Similar to Skeletal Stem Cells.

, 2022
Stem and progenitor cells play important roles in the development and maintenance of teeth and bone. Surface markers expressed in bone marrow-derived mesenchymal stem cells are also expressed in dental tissue-derived stem cells. Mouse skeletal stem cells
Miron, R J, Liang, J F, Wang, J, Zhang, Y F, Zhao, Q, Han, L T, Ji, Y T, Miron, Richard John, R.J. Miron, J. Wang, Y.F. Zhang, Y.T. Ji, L.T. Han, Q. Zhao, J.F. Liang   +14 more
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Dental Stem Cells Harvested from Third Molars Combined with Bioactive Glass Can Induce Signs of Bone Formation In Vitro

eJournal of Oral Maxillofacial Research, 2018
Objectives: The aim of this study was to assess the interaction of a bioactive glass scaffold with cells derived from dental pulp, dental follicle and periodontal ligament. Material and Methods: Impacted third molars were surgically removed from three
Gregorio Raspini, Jan Wolff, Mika Helminen, Giovacchino Raspini, Mario Raspini, George K. Sándor   +4 more
doaj   +1 more source