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The Migration and the Fate of Dental Pulp Stem Cells
Human dental pulp stem cells (hDPSCs) are adult mesenchymal stem cells (MSCs) obtained from dental pulp and derived from the neural crest. They can differentiate into odontoblasts, osteoblasts, chondrocytes, adipocytes and nerve cells, and they play a role in tissue repair and regeneration.
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Human dental pulp stem cell responses to different dental pulp capping materials [PDF]
Abstract Background Direct pulp capping is a vital pulp therapy for a pin-point dental pulp exposure. Applying a pulp capping material leads to the formation of a dentin bridge and protects pulp vitality. The aim of this study was to compare the effects of four dental materials, DyCal®, ProRoot® MTA, Biodentine™, and ...
Prasit Pavasant+7 more
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How has dental pulp stem cells isolation been conducted? A scoping review
: The objective of this study was to realize a scoping review the literature in order to identify the profile of DPSCs isolation and analyze the possible risk factors that could change the native behavior of these cells.
Camila Perelló Ferrúa+10 more
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Background Dental pulp stem cells (DPSCs) are adult stem cells with multi-directional differentiation potential derived from ectoderm. Vitro experiments have shown that adding cytokines can help DPSCs to be transformed from multipotent stem cells to ...
Pengfei Gao+4 more
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Although dental pulp and apical papilla are originated from neural crest cells, these tissues exhibit distinct characteristics. Notch signaling is one of the known signaling pathways regulating stemness and behaviors of stem cells.
Damrong Damrongsri+4 more
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Research progress on exosomes derived from dental pulp stem cells
Exosomes are bilayer lipid vesicles formed by a series of regulatory processes including endocytosis, fusion and efflux. Exosomes can be secreted by a variety of cells, including epithelial cells, mast cells, dendritic cells, T lymphocytes, and ...
HE Hongzhi, MA Dandan
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Stem Cells in Dental Pulp of Deciduous Teeth [PDF]
Dental pulp from deciduous (baby) teeth, which are discarded after exfoliation, represents an advantageous source of young stem cells. Herein, we discuss the methods of deciduous teeth stem cell (DTSC) isolation and cultivation. We show that based on these methods, at least three different stem cell populations can be identified: a population similar ...
Arnold I. Caplan, Irina Kerkis
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Epigenetic Regulation of Dental Pulp Stem Cell Fate [PDF]
Epigenetic regulation, mainly involving DNA methylation, histone modification, and noncoding RNAs, affects gene expression without modifying the primary DNA sequence and modulates cell fate. Mesenchymal stem cells derived from dental pulp, also called dental pulp stem cells (DPSCs), exhibit multipotent differentiation capacity and can promote various ...
Dan Zhou+10 more
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Monitoring Notch Signaling-Associated Activation of Stem Cell Niches within Injured Dental Pulp
Dental pulp stem/progenitor cells guarantee tooth homeostasis, repair and regeneration throughout life. The decision between renewal and differentiation of these cells is influenced by physical and molecular interactions with stromal cells and ...
Thimios A. Mitsiadis+4 more
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Characterization of stable hypoxia-preconditioned dental pulp stem cells compared with mobilized dental pulp stem cells for application for pulp regenerative therapy [PDF]
Abstract Background Dental pulp stem cells (DPSCs) have been developed as a potential source of mesenchymal stem cells (MSCs) for regeneration of dental pulp and other tissues. However, further strategies to isolate highly functional DPSCs beyond the colony-forming methods are required.
Michiyo Tominaga+5 more
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