Results 21 to 30 of about 20,256 (242)

Biomimetic Extracellular Matrix Mediated Somatic Stem Cell Differentiation: Applications in Dental Pulp Tissue Regeneration.

Frontiers in Physiology, 2015
Dental caries is one of the most widely prevalent infectious diseases in the world. It affects more than half of the world’s population. The current treatment for necrotic dental pulp tissue arising from dental caries is root canal therapy.
Sriram eRavindran, ANNE eGEORGE
doaj   +1 more source

Dental Stem Cells Harvested from Third Molars Combined with Bioactive Glass Can Induce Signs of Bone Formation In Vitro

eJournal of Oral Maxillofacial Research, 2018
Objectives: The aim of this study was to assess the interaction of a bioactive glass scaffold with cells derived from dental pulp, dental follicle and periodontal ligament. Material and Methods: Impacted third molars were surgically removed from three
Gregorio Raspini, Jan Wolff, Mika Helminen, Giovacchino Raspini, Mario Raspini, George K. Sándor   +4 more
doaj   +1 more source

Dental pulp stem cells: Potential significance in regenerative medicine [PDF]

Stomatološki glasnik Srbije, 2008
To date, three types of dental stem cells have been isolated: Dental Pulp Stem Cells (DPSC), Stem Cells From Human Exfoliated Deciduous Teeth (SHED) and Immature Dental Pulp Stem Cells (IDPC).
Todorović Vera, Marković Dejan, Milošević-Jovčić Nadežda, Petakov Marijana, Balint Bela, Čolić Miodrag, Milenković Ana, Čolak Ivana, Jokanović Vukoman, Nikolić Nebojša   +9 more
doaj   +1 more source

Bioprinting of three-dimensional dentin–pulp complex with local differentiation of human dental pulp stem cells

Journal of Tissue Engineering, 2019
Numerous approaches have been introduced to regenerate artificial dental tissues. However, conventional approaches are limited when producing a construct with three-dimensional patient-specific shapes and compositions of heterogeneous dental tissue.
Jonghyeuk Han, Da Sol Kim, Ho Jang, Hyung-Ryong Kim, Hyun-Wook Kang   +4 more
doaj   +1 more source

Nano‐Engineered Titanium Implants Loaded With Gingival Fibroblasts‐Derived Microvesicles Enhance Early Osseointegration And Soft Tissue Attachment In Vivo

Advanced Healthcare Materials, EarlyView.
Our study showed that human primary gingival fibroblast–derived microvesicles on nano‐engineered titanium implants promote early osseointegration and soft‐tissue attachment in vivo. ABSTRACT Titanium dental implants require both reliable osseointegration and peri‐implant soft tissue seal formation to ensure long‐term success. While osseointegration has
Pingping Han, Chun Liu, Anjana Jayasree, Kamil Sokolowski, Andrew Liaw, Dingbin Liu, Carlos Salomon, Karan Gulati, Ryan SB Lee, Baoxin Huang, Sašo Ivanovski   +10 more
wiley   +1 more source

Stem cells of the dental pulp

Indian Journal of Dental Research, 2012
Stem cells of the dental pulp are a population of postnatal stem cells with multilineage differentiation potential. These cells are derived from the neural ectomesenchyme, similar to most craniofacial tissues, and specific niches in the pulp have been ...
K Ranganathan, Vidya Lakshminarayanan
doaj   +1 more source

Human Atlas of Tooth Decay Progression: Identification of Cellular Mechanisms Driving the Switch from Dental Pulp Repair Toward Irreversible Pulpitis

Advanced Science, EarlyView.
Tooth decay progression transforms the dental pulp response from repair to fibrosis. At early stages, stromal cells reprogram to repair the extra cellular matrix (ECM), blood vessels, and nerves, remodel and grow, keeping repair possible. In advanced decay, hypoxia, and vessel regression, in complement with an immune switch, fuel nerve degeneration and
Hoang Thai Ha, Sofya Kosmynina, Amandine Verocq, Keremsah Ozen, Ines Tekia, Hugo Bussy, Marie Ramirez, Dima Sabbah, Chloe Goemans, Valerie Vandenbempt, Esteban N. Gurzov, Sumeet Pal Singh, Nicolas Baeyens   +12 more
wiley   +1 more source

Red Blood Cells Internalize Extracellular DNA via Apoptotic Bodies with Clinical Relevance to Cancer Patients

Advanced Science, EarlyView.
Mature red blood cells (RBCs) can capture extracellular DNA, with short fragments homologous to cfDNA. This uptake is mediated by apoptotic bodies, which induce RBC oxidative stress, deformation, and accelerated in vivo clearance. The rbcDNA abundance correlates with tumor burden and therapeutic response, highlighting its potential as a liquid biopsy ...
Zihang Zeng, Zongbi Yi, Jing Hu, Jiali Li, Yu Xu, Xiuli Guo, Qian Ji, Kaixiang Feng, Ying Zhang, Sirui Bai, Yushuang Tan, Yufei Yan, Linzhi Han, Jing Jiang, Tengfei Wang, Xiang Wang, Ziqing Zhan, Ruiying Huang, Jinfang Zhang, Conghua Xie, Binghe Xu   +20 more
wiley   +1 more source

Efficient immortalization of human dental pulp stem cells with expression of cell cycle regulators with the intact chromosomal condition.

PLoS ONE, 2020
Clinical studies have recently demonstrated that autologous transplantation of mobilized dental pulp stem cells is a safe and efficacious potential therapy for pulp regeneration.
Ai Orimoto, Seiko Kyakumoto, Takahiro Eitsuka, Kiyotaka Nakagawa, Tohru Kiyono, Tomokazu Fukuda   +5 more
doaj   +1 more source

Unraveling the Morphological and Functional Maturation Mechanisms Underlying Human Neural Development Using iPSCs‐Derived Neuronal Model

Advanced Science, EarlyView.
Using human induced pluripotent stem cells (hiPSCs)‐derived neuronal model, Tian and colleagues reveal that voltage‐gated calcium channels Cav1.2 and Cav1.3, and their mediated calcium ion influx, are essential for early morphogenesis of human neuronal development, while ECEL1 underlies human neuronal functional developmental maturation through CALM3 ...
Yue Tian, Yi‐Chun Ou, Zi‐Xian Zhang, Jie Cai, Si‐Qing Cai, Guo‐Gang Xing   +5 more
wiley   +1 more source