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Differential expression of lncRNA/miRNA/mRNA and their related functional networks during the osteogenic/odontogenic differentiation of dental pulp stem cells

Journal of Cellular Physiology, 2020
Dentin‐pulp regeneration requires dental pulp stem cells (DPSCs), but the role of long noncoding RNAs (lncRNAs) during this process remains unclear. Here, we cultured human DPSCs in osteogenic/odontogenic medium for 14 days and analyzed cells via RNA ...
Zhongjun Liu   +4 more
semanticscholar   +1 more source

Dental pulp stem cells in regenerative dentistry

Odontology, 2011
Stem cells constitute the source of differentiated cells for the generation of tissues during development, and for regeneration of tissues that are diseased or injured postnatally. In recent years, stem cell research has grown exponentially owing to the recognition that stem cell-based therapies have the potential to improve the life of patients with ...
Silvia A. Nör   +3 more
openaire   +3 more sources

Dental pulp stem cells and regeneration

Endodontic Topics, 2013
Dental pulp‐derived stem cells (DPSCs) are considered to be of great promise for use in tissue repair and regenerative medicine. DPSCs can easily be collected from discarded teeth with little ethical concerns and harvested in a minimally invasive and safe manner.
Misako Nakashima   +2 more
openaire   +2 more sources

Magnetic Cryopreservation for Dental Pulp Stem Cells

Cells Tissues Organs, 2012
Magnetic cryopreservation has been successfully used for tooth banking with satisfactory implantation outcomes, suggesting that the method preserves human periodontal ligament cells and dental pulp stem cells (DPSCs). Therefore, magnetic cryopreservation may be applied for the preservation of DPSCs; however, this method has not been evaluated yet.
Wei Chung Vivian Yang   +7 more
openaire   +3 more sources

Dental pulp stem cells in regenerative medicine

British Dental Journal, 2018
The mesenchymal stem cells (dental pulp stem cells; DPSC) found inside teeth represent a significant future source of stem cells for regenerative medicine procedures. This review describes the ontogeny of DPSC; the laboratory processing and collection of DPSC; the immuno-cytochemical characterisation of DPSC; the differentiation between adult DPSC and ...
D Aboyeji, M Orcharton, P Hollands
openaire   +3 more sources

Dental Pulp Stem Cells

2015
The identification of putative multi-potential dental stem cell populations, capable of regenerating organized tooth structures, has stimulated interest into the potential use of postnatal stem cell-based therapies to treat the damage caused by trauma, cancer, and caries.
Songtao Shi   +2 more
openaire   +2 more sources

Dental Stem Cells for Pulp Regeneration

2016
The management of pathological conditions of the dental pulp is mainly based on the disinfection of root canal system followed by the replacement of the infected or inflamed pulp tissues by inert materials. In immature teeth, the routine root canal treatment often limits the completion of root formation and protection against external root resorption ...
Kyung-San Min   +2 more
openaire   +2 more sources

Parathyroid hormone enhances the osteo/odontogenic differentiation of dental pulp stem cells via ERK and P38 MAPK pathways

Journal of Cellular Physiology, 2020
Parathyroid hormone (PTH) is a main systemic mediator of calcium and phosphate homeostasis in the bone. Dental pulp stem cells (DPSCs) have been extensively studied in the regeneration of bone and tooth tissues.
Xingyun Ge   +6 more
semanticscholar   +1 more source

EFFECT OF SOMATOSTATIN ON DENTAL PULP STEM CELLS.

Journal of biological regulators and homeostatic agents, 2015
Dental pulp stem cells (DPSCs) are multipotent stem cells with the potential to differentiate into various cell types. For this reason, they have been proposed as an alternative source for mesenchymal stem cells. Somatostatin is a peptide hormone with an inhibitory effect on several endogenous hormones.
Lauritano, D   +6 more
openaire   +4 more sources

Cellular senescence in dental pulp stem cells

Archives of Oral Biology, 2019
This short review summarizes our current knowledge about dental stem cell aging and about possible targets for the regulation of cellular senescence.A literature search was performed using a combination of keywords, e.g., stem cells, replicative senescence, differentiation potential, dental pulp, dental follicle and periodontal ligament.Previous ...
openaire   +3 more sources

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