Results 251 to 260 of about 131,553 (328)

Cellular Organization and Migration Pathways of the Ventricular–Subventricular Zone in the Juvenile Swine Brain (Sus scrofa domesticus)

open access: yesJournal of Comparative Neurology, Volume 533, Issue 7, July 2025.
A detailed structural analysis of the juvenile swine ventricular–subventricular zone reveals four distinct cellular layers and diverse neuroblast migration routes, including pathways toward the olfactory bulb and cortical regions. These features underscore the swine brain's value as a translational model for studying postnatal neurogenesis in large ...
Lucía Inés Torrijos‐Saiz   +6 more
wiley   +1 more source

GATA Transcription Factors: A Cross‐Road for Erythropoiesis, Neurodevelopment, and Synucleinopathies

open access: yesDevelopmental Neurobiology, Volume 85, Issue 3, July 2025.
ABSTRACT Alpha‐synuclein (α‐syn), a 140 amino acid protein, is abundantly expressed in the central nervous system (CNS) and in the erythrocytes, playing a pivotal role in the pathogenesis of Parkinson's disease (PD) and other synucleinopathies.
Francesco Bellomi   +7 more
wiley   +1 more source

Dentate gyrus granule cells are a locus of pathology in Scn8a developmental encephalopathy

open access: yesNeurobiology of Disease
Gain-of-function mutations in SCN8A cause developmental and epileptic encephalopathy (DEE), a disorder characterized by early-onset refractory seizures, deficits in motor and intellectual functions, and increased risk of sudden unexpected death in ...
Wenxi Yu   +6 more
doaj  

Neuronal depletion of calcium-dependent proteins in the dentate gyrus is tightly linked to Alzheimer's disease-related cognitive deficits [PDF]

open access: green, 2003
Jorge J. Palop   +7 more
openalex   +1 more source

Developmental Disturbances in Animal Models of Autism Spectrum Disorder

open access: yesDevelopmental Neurobiology, Volume 85, Issue 3, July 2025.
ABSTRACT Although the early signs of autism spectrum disorder (ASD) are widely studied, the significant ambiguity and heterogeneity in symptoms require the comparison of available models, approaches, and the search for common denominators and key indicators.
Kristof Laszlo   +3 more
wiley   +1 more source

Neuron‐Derived Extracellular Vesicles: Emerging Biomarkers and Functional Mediators in Alzheimer's Disease, With Comparative Insights Into Neurodevelopment and Aging

open access: yesDevelopmental Neurobiology, Volume 85, Issue 3, July 2025.
ABSTRACT Alzheimer's disease (AD) is one of the most common neurodegenerative disorders characterized by the accumulation of amyloid‐β (Aβ) peptide and phosphorylated tau protein in the brain. Despite intensive efforts, early diagnosis and monitoring of AD remain challenging due to the lack of reliable biomarkers that can detect the disease in its ...
Ceren Perihan Gonul   +2 more
wiley   +1 more source

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