Results 231 to 240 of about 111,284 (274)

GLP-1 selectively enhances tonic GABA_A receptor-mediated currents in mouse dentate gyrus granule cells of the ventral hippocampus. [PDF]

Front Cell Neurosci
Netsyk O, Korol SV, Birnir B, Jin Z.
europepmc   +1 more source

Protocol for culturing neurospheres from progenitor cells in the dentate gyrus of aged mouse hippocampus. [PDF]

STAR Protoc
Vafaeva O, Namchaiw P, Murray K, Diaz E, Cheng HJ.   +4 more
europepmc   +1 more source

The GluA1 cytoplasmic tail regulates intracellular AMPA receptor trafficking and synaptic transmission onto dentate gyrus GABAergic interneurons, gating response to novelty. [PDF]

Mol Psychiatry
Leana-Sandoval G, Madrid A, Kolli AV, Chinn CA, Sandoval MA, Lo I, Alizo Vera V, Simms J, Wood MA, Díaz-Alonso J.   +9 more
europepmc   +1 more source

Impaired spatial coding of the hippocampus in a dentate gyrus hypoplasia mouse model. [PDF]

Proc Natl Acad Sci U S A
Chen X, Cheng N, Wang C, Knierim JJ.
europepmc   +1 more source

γ-Aminobutyric Acid Transporter Mutation GAT1 (S295L) Substantially Impairs Neurogenesis in Dentate Gyrus. [PDF]

Brain Sci
Liu W, Yang Y, Liu Y, Ni B, Zhuang H, Chen K, Shi J, Zhu C, Wang H, Fei J.   +9 more
europepmc   +1 more source

Protective exercise responses in the dentate gyrus of Alzheimer's disease mouse model revealed with single-nucleus RNA-sequencing. [PDF]

Nat Neurosci
da Rocha JF, Lance ML, Luo R, Schlachter P, Moreira L, Iqbal MA, Kuhn P, Gardner RS, Valaris S, Islam MR, Gassner GM, Mazuera S, Healy K, Shastri S, Hibbert NB, Moran-Figueroa KV, Haley EB, Pfeiffer RD, Aygar S, Kastanenka KV, Brase L, Harari O, Benitez BA, Tucker NR, Wrann CD.   +24 more
europepmc   +1 more source

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Dentate Gyrus Immaturity in Schizophrenia

The Neuroscientist, 2019
Hippocampal abnormalities have been heavily implicated in the pathophysiology of schizophrenia. The dentate gyrus of the hippocampus was shown to manifest an immature molecular profile in schizophrenia subjects, as well as in various animal models of the disorder.
Ayda Tavitian, Wei Song, Hyman M. Schipper   +2 more
openaire   +2 more sources

Modeling the dentate gyrus

2007
Computational modeling has become an increasingly useful tool for studying complex neuronal circuits such as the dentate gyrus. In order to effectively apply computational techniques and theories to answer pressing biological questions, however, it is necessary to develop detailed, data-driven models. Development of such models is a complicated process,
Robert J, Morgan, Vijayalakshmi, Santhakumar, Ivan, Soltesz   +2 more
openaire   +2 more sources

Dentate gyrus neurogenesis and depression

2007
Major depressive disorder (MDD) is a debilitating and complex psychiatric disorder that involves multiple neural circuits and genetic and non-genetic risk factors. In the quest for elucidating the neurobiological basis of MDD, hippocampal neurogenesis has emerged as a candidate substrate, both for the etiology as well as treatment of MDD.
Amar, Sahay, Michael R, Drew, Rene, Hen
openaire   +2 more sources

Electrophysiology of dentate gyrus granule cells

Journal of Neurophysiology, 1984
The orthodromic synaptic responses, membrane properties, and responses of dentate gyrus granule cells (DGCs) to several convulsant agents were studied in the in vitro hippocampal slice preparation. Orthodromic stimulation via the perforant pathway (PP) evoked excitatory-inhibitory postsynaptic potentials (EPSP-IPSP) sequences in 27 of 34 DGCs studied.
R A, Fricke, D A, Prince
openaire   +2 more sources