Results 221 to 230 of about 62,950 (262)
The effects of bipolar disorder granule cell hyperexcitability and lithium therapy on pattern separation in a computational model of the dentate gyrus. [PDF]
Transl PsychiatrySingh S +5 more
europepmc +1 more source
Pharmacologically increasing O-GlcNAcylation increases complexity of astrocytes in the dentate gyrus of TgF344-AD rats. [PDF]
Front Aging NeurosciGarcia ML +4 more
europepmc +1 more source
ยต-Opioid Receptor Control of Glutamate/GABA Coreleasing SUM and VTA Projections to the Dentate Gyrus. [PDF]
J NeurosciOleinichenko D.
europepmc +1 more source
Survey of transcriptome analyses of hippocampal neurogenesis with focus on adult dentate gyrus stem cells. [PDF]
Front Cell Dev BiolMicheli L +5 more
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The dentate gyrus in Alzheimer's disease
Progress in Brain Research, 2007As part of the hippocampus, the dentate gyrus is considered to play a crucial role in associative memory. The reviewed data suggest that the dentate gyrus withstands the formation of plaques, tangles and neuronal death until late stages of Alzheimer's disease (AD).
Thomas G Ohm
exaly +3 more sources
An analysis of dentate gyrus function (an update)
Behavioural Brain Research, 2018In this review there will be a description of the dentate gyrus (DG) neural circuitry that mediates the operation of a variety of mnemonic processes associated with dorsal and ventral DG function in rats. Dysfunction of the dorsal DG can be shown to mediate mnemonic processing of spatially based information including a) the operation of conjunctive ...
Raymond P Kesner
exaly +3 more sources
2007
Computational modeling has become an increasingly useful tool for studying complex neuronal circuits such as the dentate gyrus. In order to effectively apply computational techniques and theories to answer pressing biological questions, however, it is necessary to develop detailed, data-driven models. Development of such models is a complicated process,
Robert J, Morgan +2 more
openaire +2 more sources
Computational modeling has become an increasingly useful tool for studying complex neuronal circuits such as the dentate gyrus. In order to effectively apply computational techniques and theories to answer pressing biological questions, however, it is necessary to develop detailed, data-driven models. Development of such models is a complicated process,
Robert J, Morgan +2 more
openaire +2 more sources
Dentate Gyrus Immaturity in Schizophrenia
The Neuroscientist, 2019Hippocampal abnormalities have been heavily implicated in the pathophysiology of schizophrenia. The dentate gyrus of the hippocampus was shown to manifest an immature molecular profile in schizophrenia subjects, as well as in various animal models of the disorder.
Ayda Tavitian +2 more
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Norepinephrine and the dentate gyrus
2007Norepinephrine's role in the dentate gyrus is assessed based on a review of what is known about its innervation and receptor patterns and its functional effects at both cellular and behavioral levels. The data support seven hypotheses: (1) Norepinephrine's functional actions are primarily mediated by beta adrenoceptors and include electrophysiological ...
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Neurotrophins in the dentate gyrus
2007Since the discovery of nerve growth factor (NGF) in the 1950s and brain-derived neurotrophic factor (BDNF) in the 1980s, a great deal of evidence has mounted for the roles of neurotrophins (NGF; BDNF; neurotrophin-3, NT-3; and neurotrophin-4/5, NT-4/5) in development, physiology, and pathology.
openaire +2 more sources