Results 91 to 100 of about 102,850,963 (222)

Incomplete Protection against Dengue Virus Type 2 Re-infection in Peru. [PDF]

PLoS Neglected Tropical Diseases, 2016
BACKGROUND:Nearly half of the world's population is at risk for dengue, yet no licensed vaccine or anti-viral drug is currently available. Dengue is caused by any of four dengue virus serotypes (DENV-1 through DENV-4), and infection by a DENV serotype is
Brett M Forshey, Robert C Reiner, Sandra Olkowski, Amy C Morrison, Angelica Espinoza, Kanya C Long, Stalin Vilcarromero, Wilma Casanova, Helen J Wearing, Eric S Halsey, Tadeusz J Kochel, Thomas W Scott, Steven T Stoddard   +12 more
doaj   +1 more source

Virus‐specific alterations in placental structure and transporter expression following maternal arbovirus infection

The Journal of Physiology, EarlyView.
Abstract figure legend Arboviruses induce virus‐specific alterations in placental structure and functional markers. Chikungunya virus (CHIKV) exposure was associated with reduced syncytiotrophoblast and syncytial knot areas, increased cytotrophoblast proliferation (Ki‐67) and thyroid transporter (MCT8) expression, reduced protective (P‐gp and BCRP ...
Cherley B. V. Andrade, Enrrico Bloise, Natália L. Silva, Jair R. S. Braga, Sharton V. A. Coelho, Veronica M. O. Nascimento, Guinever E. Imperio, Camila O. S. Nunes, Antônio J. L. A. Cunha, Marcelo A. Pascoal‐Xavier, Luciana B. Arruda, Arnaldo Prata‐Barbosa, Kristin L. Connor, Tania M. Ortiga‐Carvalho   +13 more
wiley   +1 more source

Pre-epidemic DENV-2 neutralizing antibody prevalence among symptomatic and inapparent DENV-2 infections.

, 2016
Pre-epidemic DENV-2 neutralizing antibody prevalence among symptomatic and inapparent DENV-2 infections.
Angelica Espinoza (2137915), Tadeusz J. Kochel (137222), Kanya C. Long (2137906), Wilma Casanova (2137918), Stalin Vilcarromero (372094), Eric S. Halsey (129244), Brett M. Forshey (249475), Sandra Olkowski (2137909), Steven T. Stoddard (167457), Thomas W. Scott (102260), Robert C. Reiner (2137912), Amy C. Morrison (108730), Helen J. Wearing (245189)   +12 more
core   +1 more source

Viperin is induced following dengue virus type-2 (DENV-2) infection and has anti-viral actions requiring the C-terminal end of viperin.

PLoS Neglected Tropical Diseases, 2013
The host protein viperin is an interferon stimulated gene (ISG) that is up-regulated during a number of viral infections. In this study we have shown that dengue virus type-2 (DENV-2) infection significantly induced viperin, co-incident with production ...
Karla J Helbig, Jillian M Carr, Julie K Calvert, Satiya Wati, Jennifer N Clarke, Nicholas S Eyre, Sumudu K Narayana, Guillaume N Fiches, Erin M McCartney, Michael R Beard   +9 more
doaj   +1 more source

Immune Modulatory Therapy for Severe Dengue Hemorrhagic Fever in a Patient With Mitochondrial Complex I Deficiency: A Case Report

American Journal of Medical Genetics Part A, Volume 200, Issue 12, Page 2784-2789, December 2026.
ABSTRACT Dengue virus (DENV) poses a serious global health challenge, particularly in cases of dengue hemorrhagic fever (DHF). Patients with preexisting mitochondrial disorders may be at increased risk for complications due to the specific impact of DENV on mitochondrial‐dependent cellular processes and immune function.
Audra N. Iness, Ameya S. Walimbe, Emily R. Strouphauer, Michio Hirano, Alejandro D. Iglesias, Valentina Emmanuele, Caitlin C. Griffin, Sheldon L. Kaplan, William A. Gomes, Karen K. Moeller, Stephen F. Kralik, Fernando Scaglia   +11 more
wiley   +1 more source

Anti-DENV-2 activity of sulfated GAGs.

, 2013
HMEC-1 cells were infected with DENV-2 at a MOI 1. Viral infectivity was quantified 24 h after infection by flow cytometry using an anti-DENV-2 specific antibody.
Dominique Schols (12566), Peter Vervaeke (451300), Sam Noppen (253207), Pasqua Oreste (451302), Marijke Alen (451301), Sandra Liekens (355811)   +5 more
core   +1 more source

Viral Dynamic Model‐Informed Dose Selection of Mosnodenvir Prophylaxis against DENV‐3 in a Controlled Human Infection Model

Clinical Pharmacology &Therapeutics, Volume 120, Issue 5, Page 1379-1388, November 2026.
Dengue virus (DENV) infection is a significant global health threat. Mosnodenvir (JNJ‐64281802) is a pan‐serotype small molecule antiviral blocking DENV replication. A Phase IIa study (NCT05048875) evaluated the antiviral activity, safety, and pharmacokinetics of mosnodenvir as prophylaxis against DENV‐3 in a controlled human infection model (CHIM).
Nele Goeyvaerts, Xavier Woot de Trixhe, Martine Neyens, Thomas N. Kakuda, Liesbeth Van Wesenbeeck, Annemie Buelens, Freya Rasschaert, Anna Durbin, Oliver Ackaert   +8 more
wiley   +1 more source

Dengue Serotype Differences in Urban and Semi-rural Communities in Ecuador

ACI Avances en Ciencias e Ingenierías, 2018
Dengue is a major vector-borne infection causing large outbreaks in urban communities in tropical regions. During the period 2010- 2014; 434 serum samples from febrile patients were collected from a  semi-rural community hospital located in the ...
Sully Márquez, Julio Carrera, Emilia Espín, Sara Cifuentes, Gabriel Trueba, Josefina Coloma, Joseph N. Eisenberg   +6 more
doaj   +1 more source

An integrated workflow for Mycoplasma detection and removal from cell cultures and viral stocks

Current Protocols, Volume 6, Issue 11, November 2026.
Abstract Contamination of cell cultures and viral stocks with Mycoplasma is one of the most frequent and underdiagnosed problems in laboratories working with these materials, severely affecting experimental reproducibility, data reliability, and biosafety.
Eliza Flores‐Souza, Carolina Colombelli Pacca‐Mazaro, Naiara Clemente Tavares, Camila Salles Nascimento, Tamiris Vanessa Miguel de Souza, Anna Beatriz de Oliveira Mendes, Erna Geessien Kroon, Carlos Eduardo Calzavara‐Silva, Jaquelline Germano de Oliveira   +8 more
wiley   +1 more source

BSSVS results for DENV-2.

, 2023
BackgroundAedes-borne arboviruses cause both seasonal epidemics and emerging outbreaks with a significant impact on global health. These viruses share mosquito vector species, often infecting the same host population within overlapping geographic regions.
Irma López Martínez (8555781), Lorena Preciado-Llanes (6756047), Adnan Araiza Rodriguez (16943087), Claudia Wong Arámbula (16943090), Julien Thézé (6433850), Mauricio Vázquez Pichardo (16943099), Oliver G. Pybus (8098271), Bernardo Gutierrez (6453725), Fabiola Garces Ayala (16943081), Sumali Bajaj (8971151), Abril Paulina Rodriguez Maldonado (16943078), Moritz U. G. Kraemer (3290625), María de la Luz Torre Rodriguez (16943084), Ernesto Ramírez González (16943093), Marina Escalera-Zamudio (606283), Darlan da Silva Candido (6433859), José Alberto Díaz-Quiñónez (16943096), Arturo Reyes-Sandoval (174899), Nuno R. Faria (8098247), Sarah C. Hill (3311418)   +19 more
core   +1 more source