Results 101 to 110 of about 27,818 (210)

Immunological and viral determinants of dengue severity in hospitalized adults in Ha Noi, Viet Nam. [PDF]

PLoS Neglected Tropical Diseases, 2011
The relationships between the infecting dengue serotype, primary and secondary infection, viremia and dengue severity remain unclear. This cross-sectional study examined these interactions in adult patients hospitalized with dengue in Ha Noi.158 patients
Annette Fox, Nguyen Minh Hoa Le, Cameron P Simmons, Marcel Wolbers, Heiman F L Wertheim, Thi Khuong Pham, Thi Hai Ninh Tran, Thi Minh Lien Trinh, Thi Lien Nguyen, Vu Trung Nguyen, Duc Hien Nguyen, Jeremy Farrar, Peter Horby, Walter R Taylor, Van Kinh Nguyen   +14 more
doaj   +1 more source

Allosteric Regulation of RNA Affinity by Motif V‐VI Coupling in West Nile Virus NS3 Helicase

Proteins: Structure, Function, and Bioinformatics, Volume 94, Issue 6, Page 1212-1224, June 2026.
ABSTRACT The rise of flaviviral diseases, including West Nile virus (WNV), presents a growing threat to global public health and underscores the urgent need for new therapeutic strategies. The non‐structural protein 3 helicase (NS3h) of the Orthoflavivirus genus, including WNV, is essential for viral replication and a promising antiviral target ...
Priti Roy, Martin McCullagh
wiley   +1 more source

Functional analysis of antibodies against dengue virus type 4 reveals strain-dependent epitope exposure that impacts neutralization and protection [PDF]

, 2013
Although prior studies have characterized the neutralizing activities of monoclonal antibodies (MAbs) against dengue virus (DENV) serotypes 1, 2, and 3 (DENV-1, DENV-2, and DENV-3), few reports have assessed the activity of MAbs against DENV-4.
Austin, S. Kyle, Brien, James D, Diamond, Michael S, Doranz, Benjamin J, Fremont, Daved H, Johnson, Syd, Kahle, Kristen, Pierson, Theodore C, Shrestha, Bimmi, Sukupolvi-Petty, Soila, Swayne, Sherri   +10 more
core   +2 more sources

Exploring the genetic diversity of the 3′ untranslated region (UTR) of Dengue virus

Virology Journal
Background Dengue virus (DENV), with its four antigenically distinct serotypes, is the etiological agent of dengue fever, which is endemic in tropical and subtropical regions but has recently spread to previously non-endemic areas such as Europe.
Alessandra Lo Presti, Arnold Knijn, Enrico Palermo, Alessandra D’Auria, Miriana Quaranta, Stefano Pascarella, Federica Frasca, Carolina Scagnolari   +7 more
doaj   +1 more source

Dengue Serotype Differences in Urban and Semi-rural Communities in Ecuador

ACI Avances en Ciencias e Ingenierías, 2018
Dengue is a major vector-borne infection causing large outbreaks in urban communities in tropical regions. During the period 2010- 2014; 434 serum samples from febrile patients were collected from a  semi-rural community hospital located in the ...
Sully Márquez, Julio Carrera, Emilia Espín, Sara Cifuentes, Gabriel Trueba, Josefina Coloma, Joseph N. Eisenberg   +6 more
doaj   +1 more source

Dengue Virus Capsid Protein Interaction With Nucleic Acids

BioFactors, Volume 52, Issue 3, May/June 2026.
Binding of dengue virus capsid protein (DENV C) to ssDNA alters Trp fluorescence intensity, lifetime, and anisotropy, revealing structural rearrangements in the complex and suggesting a possible association with liquid–liquid phase separation (LLPS). ABSTRACT Dengue virus (DENV) transmission has greatly increased in the last decade, partly due to the ...
Nelly M. Silva, Ana S. Martins, Nina E. Karguth, Maria J. Sarmento, Francisco J. Enguita, Roland G. Huber, Ivo C. Martins, Nuno C. Santos   +7 more
wiley   +1 more source

Dengue Virus-Infected Dendritic Cells, but Not Monocytes, Activate Natural Killer Cells through a Contact-Dependent Mechanism Involving Adhesion Molecules [PDF]

, 2017
Natural killer (NK) cells play a protective role against dengue virus (DENV) infection, but the cellular and molecular mechanisms are not fully understood.
Azeredo, Bhatt, Bozza, Chen, Chen, Chen, Costa, Costa, Fagundes, García, Handa, Ho, Homchampa, Jessie, Khor, Kumar, Kurane, Kurane, Lanier, Lim, Lisnić, Marovich, Moretta, Rölle, Schmidt, Shresta, Sridharan, St John   +27 more
core   +2 more sources

Viperin is induced following dengue virus type-2 (DENV-2) infection and has anti-viral actions requiring the C-terminal end of viperin.

PLoS Neglected Tropical Diseases, 2013
The host protein viperin is an interferon stimulated gene (ISG) that is up-regulated during a number of viral infections. In this study we have shown that dengue virus type-2 (DENV-2) infection significantly induced viperin, co-incident with production ...
Karla J Helbig, Jillian M Carr, Julie K Calvert, Satiya Wati, Jennifer N Clarke, Nicholas S Eyre, Sumudu K Narayana, Guillaume N Fiches, Erin M McCartney, Michael R Beard   +9 more
doaj   +1 more source

Analysis of climatic and seasonal effects on the oviposition activity of Aedes spp. females in municipalities of Paraná, Brazil

Austral Entomology, Volume 65, Issue 2, May 2026.
Abstract Climate and environmental changes driven by global economic activities directly affect the physiology of insect vectors, such as Aedes spp., accelerating their development, increasing the number of generations per season and increasing the risk of transmission of aetiological agents. This study aimed to analyse how local climatic variables and
Ana Carolina Felicio‐Alves, Angela Maria Palacio‐Cortés, Bryan Steven Valencia Marin, João Antônio Cyrino Zequi, Mario Antônio Navarro‐Silva   +4 more
wiley   +1 more source

Age-associated differences in clinical manifestations and laboratory parameters during a dengue virus type 4 outbreak in Argentina [PDF]

, 2017
Infection by any of the four dengue virus (DENV) serotypes produces a wide spectrum of clinical illness in humans. Differences in clinical manifestation and severity have been associated with secondary heterologous infection, patient age, and virus ...
Bono, María M., Bruno, Agostina Alejandra, Byrne, Alana Brooke, Cordoba, María Teresa, Gutierrez, Francisco Guillermo, Polack, Fernando Pedro, Quipildor, Marcelo Omar, Talarico, Laura Beatriz   +7 more
core   +1 more source