Molecular Characterization of Circulating DENV-2 During Outbreak in Northern Senegal, Rosso 2018
Globally 390 millions of people are at risk of dengue infection; over the past 50 years the virus incidence increased thirty-fold. In Senegal, an unprecedented occurrence of outbreaks and sporadic cases was noticed since 2017. In October 2018 an outbreak of DENV-2 was reported in Rosso area in the north of Senegal at the border with Mauritania.
Idrissa Dieng +12 more
openaire +2 more sources
ABSTRACT Objectives Prior studies have associated elevated ferritin levels with worse dengue outcomes but data from older adults remain limited. The aim of this study is to evaluate the serum ferritin levels and their correlation with disease severity in a population of older adults.
Sacha Orberg Temer +3 more
wiley +1 more source
Non-structural protein-1 is required for West Nile virus replication complex formation and viral RNA synthesis [PDF]
BACKGROUND: Flavivirus NS1 is a non-structural glycoprotein that is expressed on the cell surface and secreted into the extracellular space, where it acts as an antagonist of complement pathway activation.
Ambrose, Rebecca L +3 more
core +3 more sources
Subversion of early innate antiviral responses during antibody-dependent enhancement of Dengue virus infection induces severe disease in immunocompetent mice [PDF]
Dengue is a mosquito-borne disease caused by one of four serotypes of Dengue virus (DENV-1–4). Epidemiologic and observational studies demonstrate that the majority of severe dengue cases, dengue hemorrhagic fever and dengue shock syndrome (DHF/DSS ...
Ascenção, Fernando R. +17 more
core +1 more source
Genotypes of dengue virus circulate in dengue sentinel surveillance in Indonesia
Latar Belakang: Demam berdarah dengue disebabkan oleh infeksi virus dengue (DENV) yang terdiri atas serotipe 1 sampai dengan serotipe 4. Masing-masing serotipe dibedakan lagi menjadi beberapa genotipe.
Reni Herman +4 more
doaj +1 more source
Detection of dengue virus serotype 2 in aedes aegypti in Quintana Roo, Mexico, 2011 [PDF]
. In October 2011, the State Health Department announced that several laboratory-confirmed cases of dengue had occurred among residents in two neighborhoods of Benito Juarez, Quintana Roo State, Mexico. To identify the dengue virus serotype(s) temporally
Alpuche Delgado, Rafael H. +14 more
core
Alphaviral Capsid Proteins Inhibit Stress Granule Assembly via Competitive RNA Binding With G3BP1
Stress granules exert antiviral functions. This study illustrates a conserved function of alphaviral capsid proteins in modulating stress granules. Oligomerization mediated by a helical motif coupled with a positively charged intrinsically disordered region (IDR) directly competes with G3BP1 for RNA binding, thereby disrupting G3BP1‐RNA liquid–liquid ...
Yun Zhang +10 more
wiley +1 more source
Sentinel surveillance of imported dengue via travellers to Europe 2012 to 2014: TropNet data from the DengueTools Research Initiative. [PDF]
We describe the epidemiological pattern and genetic characteristics of 242 acute dengue infections imported to Europe by returning travellers from 2012 to 2014.
Angheben, Andrea +29 more
core +6 more sources
DENV and ZIKV detection in patients with acute febrile syndrome in Córdoba, Colombia
Objective: To determine simultaneous circulation of DENV serotypes and ZIKV in Córdoba, Colombia, during 2015 and 2016. Material and methods: A total of 294 samples from patients with clinical diagnosis of febrile syndrome compatible with dengue were ...
Paula A. Avilés-Vergara +6 more
doaj +1 more source
This study introduces an affordable machine learning platform for simultaneous dengue and zika detection using fluorine‐doped tin oxide thin films modified with gold nanoparticles and DNA aptamers. Designed for low‐cost, hardware‐limited devices (< $25), the model achieves 95.3% accuracy and uses only 9.4 kB of RAM, demonstrating viability for resource‐
Marina Ribeiro Batistuti Sawazaki +3 more
wiley +1 more source

