Results 61 to 70 of about 93,300,230 (204)
Liver Organoids: From Disease Modelling to Regenerative Medicine
Cell Proliferation, EarlyView.Liver organoids provide a versatile platform for disease modelling and drug discovery, leveraging stem cells and engineering techniques. They bridge research and clinical applications, offering significant potential for advancing precision medicine and regenerative therapies for liver diseases.
Tiepeng Wang +5 more
wiley +1 more source
Exploring the genetic diversity of the 3′ untranslated region (UTR) of Dengue virus
Virology JournalBackground Dengue virus (DENV), with its four antigenically distinct serotypes, is the etiological agent of dengue fever, which is endemic in tropical and subtropical regions but has recently spread to previously non-endemic areas such as Europe.
Alessandra Lo Presti +7 more
doaj +1 more source
Indonesian Journal of ChemistryDengue virus (DENV) remains a global health challenge. DENV-3 is the most virulent of the four dengue virus serotypes, requiring the identification of new inhibitors against RNA-dependent RNA polymerase (RdRp), an essential enzyme for viral replication ...
Siti Zainatun Wasilah +2 more
doaj +1 more source
Contribution of endosomal proteins EHD1 and EHD4 to the HIV‐1 replication cycle
The FEBS Journal, EarlyView.EHD1 and EHD4, two key trafficking proteins, regulate multiple stages of HIV‐1 infection: In producer cells, they help produce fully infectious virus particles, regulate Envelope protein incorporation in a cell‐type‐dependent manner, and limit the accumulation of antiviral IFITM proteins in virions.
Grégory Pacini +4 more
wiley +1 more source
Conserved dimerization architecture in C‐type lectins from virus‐vector mosquitoes
The FEBS Journal, EarlyView.C‐type lectins (CTLs) are involved in the detection of viral/microbial carbohydrates. We studied a family of soluble CTLs in the mosquito Aedes aegypti, which acts as a vector for viruses like dengue and Zika. Using crystallography, biophysics, and structure prediction approaches, we found that these proteins consistently pair together in the same ...
Mattia Bertinelli +6 more
wiley +1 more source
Serotype-specific differences in the risk of dengue hemorrhagic fever: an analysis of data collected in Bangkok, Thailand from 1994 to 2006. [PDF]
PLoS Neglected Tropical Diseases, 2010 It is unclear whether dengue serotypes differ in their propensity to cause severe disease. We analyzed differences in serotype-specific disease severity in children presenting for medical attention in Bangkok, Thailand.Prospective studies were conducted ...
Jessica R Fried +9 more
doaj +1 more source
Continuous Circulation of DENV-3 Genotype 3 in Delhi: A Single Hospital Based Surveillance Study [PDF]
, 2020 ABSTRACT BACKGROUND Delhi is hyperendemic for dengue virus (DENV) where all the four DENV have been previously reported. A constant vigilance of circulating dengue virus serotypes is important in surveillance, since the introduction of a new variant to areas affected by pre-existing serotypes ...
Abhishek Padhi +5 more
openaire +1 more source
Log Marginal Likelihoods by Path Sampling and Stepping Stone sampling for DENV-1 & DENV-3.
, 2015 Log Marginal Likelihoods by Path Sampling and Stepping Stone sampling for DENV-1 & DENV-3.
Anwar Ahmed (168240) +4 more
core +1 more source
DENV-specific IgG, but not IgA, mediates ADE in primary human monocyte-derived macrophages.
, 2023 A) Assessment of CD14 and CD163 expression on primary human monocyte-derived macrophages by flow cytometry. Dashed line indicates isotype control. B) Quantification of FcγRIIa (CD32), FcγRI (CD64), FcαR (CD89), and DC-SIGN (CD209) on primary human ...
Adam D. Wegman (11750252) +6 more
core +1 more source