Results 91 to 100 of about 47,583 (239)

Identifying the Tautomeric Form of a Deoxyguanosine-Estrogen Quinone Intermediate

open access: yesMetabolites, 2015
Mechanistic insights into the reaction of an estrogen o-quinone with deoxyguanosine has been further investigated using high level density functional calculations in addition to the use of 4-hyroxycatecholestrone (4-OHE1) regioselectivity labeled with ...
Douglas E. Stack
doaj   +1 more source

Effect of the tocotrienol-rich fraction on the lifespan and oxidative biomarkers in Caenorhabditis elegans under oxidative stress

open access: yesClinics, 2013
OBJECTIVE: This study was performed to determine the effect of the tocotrienol-rich fraction on the lifespan and oxidative status of C. elegans under oxidative stress.
Goon Jo Aan   +3 more
doaj  

Protective effect of measured physical oxidative stress load spermatozoa

open access: yesАндрология и генитальная хирургия, 2014
The immobilization stress is accompanied by disturbances of quantitative and qualitative ejaculate characteristics, the imbalance between pro- and antioxidant systems in sperm and elevated biomarker of oxidative DNA damage-8-hydroxy-2΄-deoxyguanosine ...
E. F. Galimova   +2 more
doaj   +1 more source

Formation, Repair, and Genotoxic Properties of Bulky DNA Adducts Formed from Tobacco-Specific Nitrosamines

open access: yesJournal of Nucleic Acids, 2010
4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and N′-nitrosonornicotine (NNN) are tobacco-specific nitrosamines present in tobacco products and smoke.
Lisa A. Peterson
doaj   +1 more source

A phased-addition strategy enhances the yield of RNAs obtained by in vitro transcription with modified transcriptional initiators [PDF]

open access: yes, 2015
RNA is active in multiple biological processes, not only as an information carrier but in catalyzing reactions and regulating gene expression. To understand the basis for this versatility, it is critical to establish structure-function relationships in ...
Adib, Katie
core  

Cross-sectional and longitudinal associations of acrolein exposure with pulmonary function alteration: Assessing the potential roles of oxidative DNA damage, inflammation, and pulmonary epithelium injury in a general adult population

open access: yesEnvironment International, 2022
Background: Acrolein is a significant high priority hazardous air pollutant with pulmonary toxicity and the leading cause of most noncancer adverse respiratory effects among air toxics that draws great attention. Whether and how acrolein exposure impacts
Bin Wang   +13 more
doaj  

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