Results 231 to 240 of about 53,334 (334)

Solution-Phase Synthesis of Boranophosphate and Boranophosphate/Phosphorothioate/Phosphate Chimeric Oligonucleotides via the H-Boranophosphonate Method. [PDF]

J Org Chem
Takahashi Y, Kato I, Sato K, Wada T.
europepmc   +1 more source

The COX-2 inhibitor nimesulide suppresses superoxide and 8-hydroxy-deoxyguanosine formation, and stimulates apoptosis in mucosa during early colonic inflammation in rats [PDF]

, 2000
Delphine Tardieu
openalex   +1 more source

Changes in the microbiome and metabolome in captive red kangaroos (Osphranter rufus) affected by macropod progressive periodontal disease

Australian Veterinary Journal, EarlyView.
Macropod progressive periodontal disease (MPPD) is a severe oral condition frequently observed in captive macropods, particularly red kangaroos (Osphranter rufus), yet its underlying biological features remain poorly understood. In this exploratory descriptive study, we investigated oral and fecal microbiomes and metabolomic profiles in captive red ...
Y Yoshimoto, N Nagata, R Inoue, Y Yamamoto, K Nagaoka   +4 more
wiley   +1 more source

Evaluation of change in oxidative stress in urolithiasis patients following complete stone clearance: A prospective observational study. [PDF]

Indian J Urol
Tarigopula V, Devana SK, Sharma AP, Zohmangaihi D.   +3 more
europepmc   +1 more source

Compartmentalisation in cAMP signalling: A phase separation perspective

British Journal of Pharmacology, EarlyView.
Cells rely on precise spatiotemporal control of signalling pathways to ensure functional specificity. The compartmentalisation of cyclic AMP (cAMP) and protein kinase A (PKA) signalling enables distinct cellular responses within a crowded cytoplasmic space.
Milda Folkmanaite, Manuela Zaccolo
wiley   +1 more source

Investigating the Origins of Biochemical Dysregulation in Trisomy 21 Pregnancy.

J Clin Endocrinol Metab
Buczyńska A, Sidorkiewicz I, Krętowski AJ, Zbucka-Krętowska M.   +3 more
europepmc   +1 more source

Comprehensive metabolomics profiling reveals novel biomarkers and pathways for early detection of Alzheimer's disease. [PDF]

Brain Commun
Tiwari P, Gupta A, Kaushik M, Yadav A, Anjali A, Dwivedi R, Mudgal P, Kumar Y, Tripathi M, Dada R.   +9 more
europepmc   +1 more source

Structure of (5′S)-8,5′-Cyclo-2′-deoxyguanosine in DNA

, 2011
Hai Huang, Rajat S. Das, Ashis K. Basu, Michael P. Stone   +3 more
openalex   +2 more sources

Non‐canonical PKG1 regulation in cardiovascular health and disease

British Journal of Pharmacology, EarlyView.
It is well established that the cyclic GMP‐dependent protein kinase I (PKG1) is canonically activated by cyclic guanosine monophosphate (cGMP), enabling its regulation of vascular tone, cardiac function and smooth muscle homeostasis. However, diverse non‐canonical stimuli of PKG1 have also been identified.
Jie Su, Joseph Robert Burgoyne
wiley   +1 more source

Renoprotective Effects of Goreisan via Modulation of RAAS Activity, Oxidative Stress, and AQP2 Trafficking in a Rat Model of Nephrotic Syndrome. [PDF]

Biomedicines
Shimizu M, Goto S, Yamatani S, Sakamoto K, Kono K, Fujii H.   +5 more
europepmc   +1 more source