Results 31 to 40 of about 47,583 (239)
Angewandte Chemie International Edition, 2011 DFG [IRTG 1422]
Nadler, Andre +2 more
openaire +4 more sources
Syntheses and characterizations of the in vivo replicative bypass and mutagenic properties of the minor-groove O2-alkylthymidine lesions. [PDF]
, 2014 Endogenous metabolism, environmental exposure, and treatment with some chemotherapeutic agents can all give rise to DNA alkylation, which can occur on the phosphate backbone as well as the ring nitrogen or exocyclic nitrogen and oxygen atoms of ...
Cai, Qian +3 more
core +1 more source
Reduction in squamous cell carcinomas in mouse skin by dietary zinc supplementation. [PDF]
, 2016 Inadequate dietary Zn consumption increases susceptibility to esophageal and other cancers in humans and model organisms. Since Zn supplementation can prevent cancers in rodent squamous cell carcinoma (SCC) models, we were interested in determining if it
Druck, Teresa +9 more
core +2 more sources
Design, Synthesis, and Analysis of Minor Groove Binder Pyrrolepolyamide-2′-Deoxyguanosine Hybrids
Journal of Nucleic Acids, 2010 Pyrrolepolyamide-2′-deoxyguanosine hybrids (Hybrid 2 and Hybrid 3) incorporating the 3-aminopropionyl or 3-aminopropyl linker were designed and synthesized on the basis of previously reported results of a pyrrolepolyamide-adenosine hybrid (Hybrid 1 ...
Etsuko Kawashima +3 more
doaj +1 more source
PLoS ONE, 2020 Adult growth hormone deficiency (GHD) is being increasingly recognized to cause premature mortality exacerbated by oxidative stress. A case-control observational study has been performed with the primary objective of evaluating new parameters of ...
Antonio Mancini +6 more
doaj +1 more source
Hayati Journal of Biosciences, 2017 Human fertility and its correlation to ovarian function and cytological changes are linked to ever-increasing use of mobile phones. Wireless communications have become a critical topic of concern because of an increasing number of studies in this field ...
Ali Saeed Hammoodi Alchalabi +6 more
doaj +1 more source
Journal of Biological Chemistry, 1982 Detergent-disrupted vesicular stomatitis virus carried out in vitro transcription at a reduced rate in the presence of deoxyguanosine triphosphate. The transcripts annealed completely to excess vesicular stomatitis virus genomic RNA and consistent of the short leader RNA and even polyadenylated messenger RNA.
M Schubert, R A Lazzarini
openaire +3 more sources
Ab-initio study of model guanine assemblies: The role of pi-pi coupling and band transport
, 2001 Several assemblies of guanine molecules are investigated by means of first-principle calculations. Such structures include stacked and hydrogen-bonded dimers, as well as vertical columns and planar ribbons, respectively, obtained by periodically ...
A. Aviram +40 more
core +1 more source
Interaction of Nucleosides and Related Compounds with Nucleic Acids as Indicated by the Change of Helix-Coil Transition Temperature [PDF]
, 1962 A series of compounds has been tested for effectiveness in lowering the melting temperature of poly A and of thymus DNA. The order of increasing activity was found to be: adonitol, methyl riboside (both negligible) < cyclohexanol < phenol, pyrimidine ...
Helmkamp, G. K. +2 more
core +1 more source
Oligonucleotide Incorporation of 8-Thio-2‘-deoxyguanosine [PDF]
Organic Letters, 2004 [reaction: see text] 8-Thio-2'-deoxyguanosine (SdG) is a useful analogue of the abundant promutagen 8-oxo-2'-deoxyguanosine (OdG). Its synthesis and DNA incorporation using standard phosphoramidite chemistry is reported. To prevent oxidation during DNA synthesis, the sulfur was protected as a 2-(trimethylsilyl)ethyl sulfide.
Timothy J. Gill +3 more
openaire +4 more sources