Results 61 to 70 of about 53,334 (334)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Mitochondrial DNA Depletion Syndrome
Pediatric Neurology Briefs, 2002 Twenty patients with myopathic mitochondrial DNA (mtDNA) depletion syndrome (MDS) were screened for mutations in thymidine kinase 2 (TK2) and deoxyguanosine kinase (dGK) genes at Columbia University, New York, NY.
J Gordon Millichap
doaj +1 more source
PLoS ONE, 2020 Adult growth hormone deficiency (GHD) is being increasingly recognized to cause premature mortality exacerbated by oxidative stress. A case-control observational study has been performed with the primary objective of evaluating new parameters of ...
Antonio Mancini +6 more
doaj +1 more source
Molecular biomarkers and toxic consequences of impact by organic pollution in aquatic organisms [PDF]
, 1994 Organic contaminants are readily bioaccumulated by aquatic organisms. Exposure to and toxic effects of contaminants can be measured in terms of the biochemical responses of the organisms (i.e. molecular biomarkers).
Förlin, L. +2 more
core
Analytics of oxidative stress markers in the early diagnosis of oxygen DNA damage [PDF]
, 2017 Under homeostatic conditions, an equilibrium state between amounts of free radicals formed and their scavenging is observed. Free radicals are destructive only when present in excess.
Dabrowska, Natalia, Wiczkowski, Andrzej
core +1 more source
Frailty Exacerbates Disability in Progressive Multiple Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background To evaluate frailty in severe progressive multiple sclerosis (PMS) and to investigate the underlying mechanisms. Methods This prospective, cross‐sectional, multicenter study enrolled a late severe PMS group requiring skilled nursing (n = 53) and an age, sex, and disease duration‐matched control PMS group (n = 53).
Taylor R. Wicks +10 more
wiley +1 more source
Molecules, 2022 Reactive oxygen species (ROS) are continuously produced in living cells due to metabolic and biochemical reactions and due to exposure to physical, chemical and biological agents.
Ana-Maria Chiorcea-Paquim
doaj +1 more source
Aortic pathology from protein kinase G activation is prevented by an antioxidant vitamin B12 analog. [PDF]
, 2019 People heterozygous for an activating mutation in protein kinase G1 (PRKG1, p.Arg177Gln) develop thoracic aortic aneurysms and dissections (TAAD) as young adults.
Boss, Gerry R +15 more
core +1 more source
Environmental conditions can modulate the links among oxidative stress, age, and longevity [PDF]
, 2017 Understanding the links between environmental conditions and longevity remains a major focus in biological research. We examined within-individual changes between early- and mid-adulthood in the circulating levels of four oxidative stress markers linked ...
Boner, Winnie +5 more
core +1 more source
Near‐Infrared Organic Photovoltaic Electrodes for Subretinal Neurostimulation
Advanced Functional Materials, EarlyView.Organic photovoltaic electrodes based on the D18:Y6 blend enable precise and light‐controlled activation of retinal ganglion cells in a degenerating retina. NIR Light‐driven activation of retinal ganglion cells, tunable stimulation parameters, and biocompatibility with human retinal organoids highlight their potential for next‐generation prosthetics ...
Andrea Corna +10 more
wiley +1 more source