Results 81 to 90 of about 47,583 (239)

Prognostic significance of 8-hydroxy-2′-deoxyguanosine in solid tumors: a meta-analysis

BMC Cancer, 2019
Background High level of reactive oxygen species (ROS) has been detected in almost all cancers, which make it become one of the best-characterized phenotypes in cancers.
Xiangcheng Qing, Deyao Shi, Xiao Lv, Baichuan Wang, Songfeng Chen, Zengwu Shao   +5 more
doaj   +1 more source

Assessment of oxidative damage to proteins and DNA in urine of newborn infants by a validated UPLC-MS/MS approach.

PLoS ONE, 2014
The assessment of oxidative stress is highly relevant in clinical Perinatology as it is associated to adverse outcomes in newborn infants. This study summarizes results from the validation of an Ultra Performance Liquid Chromatography-tandem Mass ...
Julia Kuligowski, Isabel Torres-Cuevas, Guillermo Quintás, Denise Rook, Johannes B van Goudoever, Elena Cubells, Miguel Asensi, Isabel Lliso, Antonio Nuñez, Máximo Vento, Javier Escobar   +10 more
doaj   +1 more source

Association between metal exposure and oxidative stress in preschool children and the moderating role of urinary creatinine

Environmental Chemistry and Ecotoxicology
The association between childhood metal exposure and oxidative stress levels is of paramount importance, as children are a susceptible group to metal toxicity and elevated oxidative damage has been linked to a variety of diseases.
Mei Liu, Yanfang Cheng, Jia He, Lin Zhang, Juntao Li, Lei Tan   +5 more
doaj  

Mitochondrial deoxyguanosine kinase is required for female fertility in mice

Acta Biochimica et Biophysica Sinica
Mitochondrial homeostasis plays a pivotal role in oocyte maturation and embryonic development. Deoxyguanosine kinase (DGUOK) is a nucleoside kinase that salvages purine nucleosides in mitochondria and is critical ...
Gao Yake, Dong Rui, Yan Jiacong, Chen Huicheng, Sang Lei, Yao Xinyi, Fan Die, Wang Xin, Zuo Xiaoyuan, Zhang Xu, Yang Shengyu, Wu Ze, Sun Jianwei   +12 more
doaj   +1 more source

Deoxyguanosine Triphosphate as a Possible Toxic Metabolite in the Immunodeficiency Associated with Purine Nucleoside Phosphorylase Deficiency [PDF]

, 1978
Amos Cohen, Lorraine J. Gudas, Arthur J. Ammann, G.E.J. Staal, David W. Martin   +4 more
openalex   +1 more source

Life fingerprints of nuclear reactions in the body of animals [PDF]

, 2010
Nuclear reactions are a very important natural phenomenon in the universe. On the earth, cosmic rays constantly cause nuclear reactions. High energy beams created by medical devices also induce nuclear reactions in the human body.
Ci-yi Liu, Ji-hui Han, Ji-hui Su, Jun Zeng, Qi-yin Sun, Quan-shi Zhang, Tao Sun, Wen-hui Xie, Xiao-jia Cai   +8 more
core   +1 more source

Hydrogen peroxide thermochemical oscillator as driver for primordial RNA replication

, 2014
This paper presents and tests a previously unrecognised mechanism for driving a replicating molecular system on the prebiotic earth. It is proposed that cell-free RNA replication in the primordial soup may have been driven by self-sustained oscillatory ...
Ball, Rowena, Brindley, John
core   +1 more source

Metabolomics reveals early pregnancy biomarkers in sows: a non-invasive diagnostic approach

Frontiers in Veterinary Science
In an effort to enhance reproductive management and reduce non-productive periods in swine breeding, this study presents a novel, non-invasive metabolomics approach for the identification of early pregnancy biomarkers in sows.
Yujun Ren, Qingze Zhang, Fan He, Menfan Qi, Binbin Fu, Huapeng Zhang, Tao Huang, Tao Huang   +7 more
doaj   +1 more source

Cholesterol Exchange, DNA Damages, Apoptosis and Necrosis of Blood Cells in Severe Concomitant Injury

Общая реаниматология, 2008
Objective: to study a number of free-radical reactions, the parameters of cholesterol exchange, and the extent of blood cell DNA damages in victims early after concomitant injury. Subjects and methods.
V. V. Moroz, V. I. Reshetnyak, M. Yu. Muravyeva, A. K. Zhanatayev, Yu. V. Marchenkov, A. D. Durnev   +5 more
doaj   +1 more source

Benzo[a]pyrene diol epoxide covalently binds to deoxyguanosine and deoxyadenosine in DNA [PDF]

, 1977
Thomas Meehan, Kenneth Straub, M. Calvin
openalex   +1 more source