Results 61 to 70 of about 192,494 (228)

Intrapleural tissue plasminogen activator and deoxyribonuclease administered concurrently and once daily for complex parapneumonic pleural effusion and empyema

open access: yes, 2023
Background: Pleural infection is life-threatening and increasingly prevalent. In addition to usual care, twice-daily, separate administration of tissue plasminogen activator and deoxyribonuclease (tPA-DNase) reduces radiological pleural opacity with ...
Timothy Ryder   +5 more
core   +1 more source

Plasma DNA and deoxyribonuclease are associated with glucose metabolism in healthy mice.

open access: yesPLoS ONE, 2022
It is currently unknown why obesity leads in some patients to prediabetes and metabolic syndrome. Microinflammation potentially caused by extracellular DNA is supposed to be involved.
Katarína Kmeťová   +5 more
doaj   +1 more source

Nonthermal plasma approaches for combating implant‐associated infections: A compendious review

open access: yesVIEW, EarlyView.
Implant‐associated infections pose serious clinical challenges. Non‐thermal plasma (NTP) modifications overcome this bottleneck in distinct ways relative to traditional sterilization methods. Gas‐phase plasmas generate highly energetic species, UV radiation and reactive oxygen/nitrogen species (RONS), which alter the implant surface properties.
A. M. Trimukhe   +8 more
wiley   +1 more source

Apo10 and TKTL1 as novel liquid biopsy biomarkers for early detection of gastrointestinal malignancies

open access: yesVIEW, EarlyView.
(A) Overview of the study population and schematic illustration showing tumor‐derived apoptotic and metabolic biomarkers, Apo10 and TKTL1, being phagocytosed by circulating monocytes and subsequently detected in peripheral blood. (B) Illustration of the epitope detection in monocytes (EDIM) strategy, using a flow‐cytometric gating approach based on ...
Zhiying Mao   +8 more
wiley   +1 more source

A PROTEIN INHIBITOR OF ACID DEOXYRIBONUCLEASES [PDF]

open access: yesProceedings of the National Academy of Sciences, 1969
A protein extracted and partially purified (about 100-fold) from mouse liver is able to inhibit the acid DNases from different tissues and species, whereas pancreatic DNase and E. coli endonuclease I are not inhibited.
P, Lesca, C, Paoletti
openaire   +2 more sources

Lactate‐Primed NETosis Modulates Hepatic Regeneration During Acute Liver Failure via the TLR9/KLF15/AJUBA Axis

open access: yesCell Proliferation, EarlyView.
This study elucidates a novel Kupffer cell‐neutrophil‐hepatocyte axis that drives metabolic‐immune crosstalk during acute liver failure. Specifically, lactate‐primed NETs release links metabolic reprogramming to NETosis‐induced regenerative failure in hepatocytes via the TLR9/KLF15/AJUBA axis.
Jin Guo   +5 more
wiley   +1 more source

Rutin as Deoxyribonuclease I Inhibitor

open access: yesChemistry & Biodiversity, 2019
AbstractDNase I inhibitory potential of water extract of nine Hypericum species (H. umbellatum, H. barbatum, H. rumeliacum, H. rochelii, H. perforatum, H. tetrapterum, H. olympicum, H. hirsutum, H. linarioides) and the most important Hypericum secondary metabolites (hypericin, hyperforin, quercetin, and rutin) was investigated.
Ana Kolarevic   +7 more
openaire   +3 more sources

PLIN5 Protects Against Ang II‐Induced Podocyte Lipotoxicity by Interacting With FKBP8 and Preserving Lipid Droplet–Mitochondria Contact

open access: yesCell Proliferation, EarlyView.
PLIN5‐FKBP8 tethers lipid droplets to mitochondria to counteract Ang II‐induced lipotoxicity. ABSTRACT Chronic kidney disease (CKD) remains a major global health challenge. Angiotensin II (Ang II)‐induced lipotoxicity is an important contributor to podocyte injury.
Ping Wang   +7 more
wiley   +1 more source

ACID DEOXYRIBONUCLEASE IN RAT LIVER CELL NUCLEI ISOLATED IN THE PRESENCE OF CALCIUM IONS

open access: yes, 1964
Nuclear fractions centrifugally separated from rat liver homogenates in isotonic sucrose or in water, containing in each case 1.8 mM CaCl2, and washed repeatedly in the same media, retained a considerable amount of acid deoxyribonuclease activity ...
KARL F. SWINGLE, LEONARD J. COLE
core   +1 more source

Unknown Areas of Activity of Human Ribonuclease Dicer: A Putative Deoxyribonuclease Activity

open access: yesMolecules, 2020
The Dicer ribonuclease plays a crucial role in the biogenesis of small regulatory RNAs (srRNAs) by processing long double-stranded RNAs and single-stranded hairpin RNA precursors into small interfering RNAs (siRNAs) and microRNAs (miRNAs), respectively ...
Marta Wojnicka   +2 more
doaj   +1 more source

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