Results 101 to 110 of about 170,315 (251)
Role of Cytolethal Distending Toxin in Altered Stool Form and Bowel Phenotypes in a Rat Model of Post-infectious Irritable Bowel Syndrome. [PDF]
, 2012 Background/aimsCampylobacter jejuni infection is a leading cause of acute gastroenteritis, which is a trigger for post-infectious irritable bowel syndrome (PI-IBS). Cytolethal distending toxin (CDT) is expressed by enteric pathogens that cause PI-IBS. We
Alpern, Joel +12 more
core +1 more source
Advanced Science, Volume 13, Issue 1, 5 January 2026.EGFR mutations drive ERK/c‐Jun–mediated transcriptional activation of CD73, elevating adenosine levels and fostering an immunosuppressive TME by impairing DC maturation and CD8⁺ T cell priming. The pH‐responsive nanodrug F127ZIF‐8AB680 selectively inhibits CD73, normalizes adenosine metabolism, and re‐establishes effective anti‐tumor immunity ...
Xiaoling Shang +14 more
wiley +1 more source
A Deoxyribonuclease from Calf Spleen. II. Mode of Action [PDF]
, 1957 When highly polymerized deoxyribonucleic acid is digested with pancreatic DNase and the digest further degraded with phosphodiesterase from intestinal mucose or snake venom, the mononucleotides formed are 5'-phosphates.
Koerner, James F., Sinsheimer, Robert L.
core
Advanced Science, Volume 13, Issue 1, 5 January 2026.Metal–phenolic network (MPN) nanoparticles with neuroprotective functions are integrated into decellularized extracellular matrix (dECM) to obtain biomimetic composite fibrous scaffold MPN@dECM NFs by electrospinning, which protects spared neurons from secondary degeneration by suppressing excitotoxicity and inflammation, and promotes directional ...
Shu Chen +4 more
wiley +1 more source
Development of a reporter gene assay to identify control elements required for dosage compensation in Drosophila Melanogaster : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Genetics at Massey University [PDF]
, 1998 Dosage compensation (equalisation of X-linked gene products) occurs in Drosophila melanogaster by a two-fold transcriptional increase of X-linked gene expression in the male.
Fitzsimons, Helen
core
Strategies to prevent the occurrence of resistance against antibiotics by using advanced materials [PDF]
, 2018 This is a post-peer-review, pre-copyedit version of an article published in Applied microbiology and biotechnology The final authenticated version is available online at: http://dx.doi.org/10.1007/s00253-018-8776-0Drug resistance occurrence is a global ...
Bassegoda Puigdomenech, Arnau +3 more
core +2 more sources
Active Site of Deoxyribonuclease I . III. Effects of Radiation on Deoxyribonuclease I in Dry State [PDF]
Journal of Radiation Research, 1963 The mechanisms of inactivation of deoxyribonuclease by direct action of radiation have been studied. By testing kinetic properties of the enzyme and its tryptophan content, it seems likely that when the enzyme molecule absorbs energy from radiation, the energy is transferred to the ‘active site’ of the enzyme.
openaire +1 more source
Clinical and Translational Medicine, Volume 16, Issue 1, January 2026.TANs drive ICI resistance via antitumour immune remodelling, angiogenesis promotion, and elevation of tumour mutation burden Neutrophil biomarkers (e.g., NLR, TAN abundance) show strong predictive value for ICI response and prognosis. Targeting TAN recruitment, polarization, function and NETosis represents a promising strategy to overcome ICI ...
Ying Ning +7 more
wiley +1 more source
The Biology of the Cytolethal Distending Toxins
Toxins, 2011 The cytolethal distending toxins (CDTs), produced by a variety of Gram-negative pathogenic bacteria, are the first bacterial genotoxins described, since they cause DNA damage in the target cells. CDT is an A-B2 toxin, where the CdtA and CdtC subunits are
Teresa Frisan +3 more
doaj +1 more source
, 2012 The ejaculated semen consists of two major components viz. sperm cells (spermatozoa) and the fluid part obtained after centrifugation called seminal plasma.
P Perumal
core +2 more sources