Results 111 to 120 of about 170,315 (251)

Biochemical and Comparative Proteomic Analyses Delineate the Anti‐Ovarian Carcinogenic Roles of Modified Calycosin

Food Science &Nutrition, Volume 14, Issue 1, January 2026.
The modified calycosin derivative H10 was more effective in inhibiting cell proliferation through G0/G1 cell cycle arrest, together with inhibiting the migration and colony formation abilities of ovarian cancer cell lines SKOV3 and A2780. Comparative proteomic analysis coupled with Ingenuity Pathway Analysis further delineated calycosin derivative H10 ...
Fuhong Yang, Xin Li, Hanchi Gao, Pei Yao, Xian Qin, Xiao Lin, Keng Po Lai, Jing Tian, Jian Chen   +8 more
wiley   +1 more source

Evidence for the role of proteoglycans in cation-mediated gene transfer [PDF]

, 1996
We report evidence that gene complexes, consisting of polycations and plasmid DNA enter cells via binding to membrane-associated proteoglycans. Treatment of HeLa cells with sodium chlorate, a potent inhibitor of proteoglycan sulfation, reduced luciferase
Baldeschwieler, John D., Mislick, Kimberly A.   +1 more
core   +1 more source

Radioprotection by inactivation of deoxyribonuclease I

The FASEB Journal, 2009
Gamma radiation‐induced cell death is associated with and mediated by enzymatic DNA fragmentation. A nuclease that produces this fragmentation of DNA is unknown. To determine whether deoxyribonuclease I (DNase I), a major cytotoxic/apoptotic nuclease expressed in all cells and tissues, can mediate gamma ...
Yevgeniy O. Apostolov, Izoumroud Soultanova, Alena V. Savenka, Osman O. Bagandov, Xiaoyan Yin, Anna G. Stewart, Richard B. Walker, Alexei G. Basnakian   +7 more
openaire   +1 more source

Investigating the mechanism of aluminum resistance conferred by aluminum resistance protein 1

Protein Science, Volume 35, Issue 1, January 2026.
Abstract Aluminum does not play any role in essential biological processes, but in acidic conditions it becomes biologically reactive and highly toxic even at low concentrations. Eukaryotes have developed numerous strategies for detoxification, one of which relies on membrane proteins.
Pavlo Stehantsev, Artem Stetsenko, Pavla Herynková, Andrei Zupnik, Carsten Takens, Olga Zimmermannova, Hana Sychrova, Albert Guskov   +7 more
wiley   +1 more source

Purification and characterization of deoxyribonuclease from small intestine of camel Camelus dromedarius

Journal of Genetic Engineering and Biotechnology, 2017
The chromatography of deoxyribonuclease (DNase) from small intestine of camel Camelus dromedarius by DEAE-Sepharose separated three isoforms DNase 1, DNase 2 and DNase 3. The DNase 3 was purified to homogeneity by chromatography on Sephacryl S-200.
Somia S. Abdel-Gany, Mohamed O. El-Badry, Afaf S. Fahmy, Saleh A. Mohamed   +3 more
doaj   +1 more source

Class of {varphi}X174 Mutants Relatively Deficient in Synthesis of Viral RNA [PDF]

, 1974
Nonpermissive cells infected with {varphi}X174 gene D amber mutants synthesized some sixfold less viral RNA than permissive cells. The decrease was unaffected by increasing the multiplicity of infection and was a consequence of an overall decrease in all
Clements, J. Barklie, Sinsheimer, Robert L.   +1 more
core  

Synergistic Effects in Condensed DNA Framework‐Mediated Synthesis of Amorphous Nanoalloys for Enhanced Electrocatalytic Oxygen Evolution

Small Structures, Volume 7, Issue 1, January 2026.
The condensed DNA framework generates a self‐confined space that facilitates the constrained synthesis of FeCoNi amorphous nanoalloys (FeCoNi ANAs), while simultaneously acting as a dispersant and adhesive, as well as synergistically modulating the coupling of the lattice oxygen mechanism (LOM) and the adsorbate evolution mechanism (AEM), thereby ...
Zhuang Cai, Rui Gao, Jianbang Wang, Huajie Liu   +3 more
wiley   +1 more source

Coordinated transcriptional regulation between a reactive oxygen species-responsive gene network and the circadian clock in Arabidopsis thaliana : a thesis presented in partial fulfillment of the requirements for the degree of Doctor of Philosophy in Plant Biology at Massey University, Plant Biology, New Zealand [PDF]

, 2012
Most organisms have evolved endogenous biological clocks as internal timekeepers to fine-tune physiological processes to the external environment. Energetic cycles such as photosynthesis and glycolytic cycles are physiological processes that have ...
Lai, Alvina Grace
core  

Caffeine Inhibits EGF-Stimulated Trophoblast Cell Motility through the Inhibition of mTORC2 and Akt. [PDF]

, 2012
Impaired trophoblast invasion is associated with pregnancy disorders such as early pregnancy loss and preeclampsia. There is evidence to suggest that the consumption of caffeine during pregnancy may increase the risk of pregnancy loss; however, little is
Alison E. Wallace, Bauer, Beavo, Biadasiewicz, Boulbes, Brent, Brooke Lumicisi, Brosens, Burton, CARE Study Group, Cartwright, Cartwright, Cartwright, Chui, Di Fiore, Fabro, Foukas, Goldstein, Gude, Guy S. Whitley, Hofmann, Isobelle Grant, Jang, Judith E. Cartwright, Julien, LaMarca, LaMarca, LaMarca, Lee, Liu, Marone, Maslova, Mei, Olayioye, Omori, Pollheimer, Robertson, Spindle, Stefanidou, Tsygankova, Wadge, Weng, Yarden, Yarden, Yoshino, Zhang, Zoncu   +46 more
core   +1 more source

Integrated Multiomics Analysis Reveals a Migrasome‐Related Signature for Prognosis and Immunotherapy Response in Lung Adenocarcinoma

Human Mutation, Volume 2026, Issue 1, 2026.
Background Migrasomes, a newly identified subtype of extracellular vesicles generated during cell migration, play crucial roles in tumor microenvironment modulation. However, their systematic characterization in lung adenocarcinoma (LUAD) remains unexplored.
Jiayu Zhou, Tianye Song, Nengzheng Wang, Ce Liang, Ming Jiang, Xu Zhang, Hong Gao, Qingqing Feng, Sujit Nair   +8 more
wiley   +1 more source