Results 31 to 40 of about 159,619 (187)

Mining Clinical Case Reports to Identify New Lines of Investigation in Alzheimer’s Disease: The Curious Case of DNase I

open access: yesJournal of Alzheimer's Disease Reports, 2019
Mining the case report literature identified an intriguing, yet neglected finding: Deoxyribonuclease I (DNase I) as a possible treatment for Alzheimer’s disease.
Neil R. Smalheiser
doaj   +1 more source

Interaction of iodoacetamidofluorescein‐labelled tropomyosin with deoxyribonuclease I [PDF]

open access: yesFEBS Letters, 1989
5‐Iodoacetamidofluorescein (IAF) reacted with rabbit cardiac muscle tropomyosin (TM) to yield a highly fluorescent product, IAF‐TM. The extent of labelling reached one fluorescein group per TM molecule in solutions at pH 8.5. While fluorescence polarization values for IAF‐TM solutions were unaffected by the presence or absence of KCl, addition of ...
Burtnick, L.D., Wong, M.K.C.
openaire   +2 more sources

Study on zeolitic imidazolate framework nanocomposites for biofilm eradication

open access: yes上海师范大学学报. 自然科学版, 2023
In recent years, novel antibacterial nanomaterials show a non-negligible potential in anti-biofilm due to their specific physiochemical properties and mechanism of action.
HOU Jiaxin   +3 more
doaj   +1 more source

AAV‐mediated gene transfer of DNase I in the liver of mice with colorectal cancer reduces liver metastasis and restores local innate and adaptive immune response

open access: yesMolecular Oncology, 2020
Liver metastasis is the main cause of colorectal cancer (CRC)‐related death. Neutrophil extracellular traps (NETs) play important roles in CRC progression.
Yujia Xia   +14 more
doaj   +1 more source

Genetically Engineered Cellular Nanovesicle as Targeted DNase I Delivery System for the Clearance of Neutrophil Extracellular Traps in Acute Lung Injury

open access: yesAdvanced Science, 2023
Acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) are prevalent critical illnesses with a high mortality rate among patients in intensive care units.
Yang Du   +5 more
doaj   +1 more source

Global identification of prokaryotic glycoproteins based on an Escherichia coli proteome microarray. [PDF]

open access: yesPLoS ONE, 2012
Glycosylation is one of the most abundant protein posttranslational modifications. Protein glycosylation plays important roles not only in eukaryotes but also in prokaryotes.
Zong-Xiu Wang   +8 more
doaj   +1 more source

Bacterial Genotoxin-Coated Nanoparticles for Radiotherapy Sensitization in Prostate Cancer

open access: yesBiomedicines, 2021
Prostate cancer (PCa) is one of the most commonly diagnosed cancers in men and usually becomes refractory because of recurrence and metastasis. CD44, a transmembrane glycoprotein, serves as a receptor for hyaluronic acid (HA).
Yu-An Chen   +12 more
doaj   +1 more source

Early DNase-I therapy delays secondary brain damage after traumatic brain injury in adult mice

open access: yesScientific Reports, 2023
Traumatic brain injury (TBI) causes the release of danger-associated molecular patterns (DAMP) from damaged or dead cells, which contribute to secondary brain damage after TBI.
Tobias J. Krämer   +9 more
doaj   +1 more source

A Fast and Efficient Decellularization Method for Tissue Slices

open access: yesBio-Protocol, 2022
The study and use of decellularized extracellular matrix (dECM) in tissue engineering, regenerative medicine, and pathophysiology have become more prevalent in recent years.
Maria Narciso   +7 more
doaj   +1 more source

Natural Biomaterials for Osteochondral Repair: From Source to Strategy

open access: yesAdvanced Healthcare Materials, EarlyView.
Biological origin‐guided overview of natural biomaterials and therapeutic strategies for osteochondral tissue engineering. The circular diagram categorizes representative materials and strategies into plant/algae‐derived, microbial‐derived, animal‐derived, and human‐derived sources, centered on an osteochondral defect repair model.
Hengyu Liu   +5 more
wiley   +1 more source

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