Results 21 to 30 of about 159,619 (187)

Rutin as Deoxyribonuclease I Inhibitor

Chemistry & Biodiversity, 2019
AbstractDNase I inhibitory potential of water extract of nine Hypericum species (H. umbellatum, H. barbatum, H. rumeliacum, H. rochelii, H. perforatum, H. tetrapterum, H. olympicum, H. hirsutum, H. linarioides) and the most important Hypericum secondary metabolites (hypericin, hyperforin, quercetin, and rutin) was investigated.
Ana Kolarevic, Aleksandra Pavlovic, Aleksandra Djordjevic, Jelena Lazarevic, Sasa Savic, Gordana Kocic, Marko Anderluh, Andrija Smelcerovic   +7 more
openaire   +3 more sources

Redox metabolism correlates with cellular turnover and clinical phenotype of papillary thyroid carcinoma and colloid goiter

Archives of Medical Science, 2019
Introduction Papillary thyroid carcinoma (PTC) and colloid goiter (CG) represent the most common thyroid malignant and benign diseases, respectively.
Branislav Rovcanin, Kristina Gopcevic, Dusan Kekic, Vladan Zivaljevic, Aleksandar Diklic, Svetislav Tatic, Milan Jovanovic, Bozidar Odalovic, Ivan Paunovic   +8 more
doaj   +1 more source

Virus-Like Cytosolic and Cell-Free Oxidatively Damaged Nucleic Acids Likely Drive Inflammation, Synapse Degeneration, and Neuron Death in Alzheimer’s Disease

Journal of Alzheimer's Disease Reports, 2023
Oxidative stress, inflammation, and amyloid-β are Alzheimer’s disease (AD) hallmarks that cause each other and other AD hallmarks. Most amyloid-β-lowering, antioxidant, anti-inflammatory, and antimicrobial AD clinical trials failed; none stopped or ...
Owen Davis Sanders
doaj   +1 more source

Composite Hydrogel Modulates Intrinsic Immune-Cascade Neovascularization for Ocular Surface Reconstruction after Corneal Chemical Injury

Gels, 2023
Ocular alkali burns recruit neutrophils and triggers neutrophil extracellular trap (NET)-neovascularization cascade effects that limit ocular surface reconstruction and functional repair.
Jun Zhang, Kun Xi, Guohua Deng, Xi Zou, Peirong Lu   +4 more
doaj   +1 more source

3’-Methyl-4-thio-1H-tetrahydropyranspiro-5’-hydantoin platinum complex as a novel deoxyribonuclease I inhibitor [PDF]

Pharmacia
Deoxyribonuclease I (DNase I) is one of the main nucleases involved in deoxyribonucleic acid (DNA) degradation during apoptosis. It catalyzes the hydrolytic cleavage of DNA, producing 5‘-oligonucleotides.
Ana Marković, Mariyana Atanasova, Rossen Buyukliev, Adriana Bakalova, Andrija Šmelcerović, Emiliya Cherneva   +5 more
doaj   +3 more sources

New Cytoplasmic Virus-Like Elements (VLEs) in the Yeast Debaryomyces hansenii

Toxins, 2021
Yeasts can have additional genetic information in the form of cytoplasmic linear dsDNA molecules called virus-like elements (VLEs). Some of them encode killer toxins. The aim of this work was to investigate the prevalence of such elements in D.
Xymena Połomska, Cécile Neuvéglise, Joanna Zyzak, Barbara Żarowska, Serge Casaregola, Zbigniew Lazar   +5 more
doaj   +1 more source

Blood neutrophil extracellular traps: a novel target for the assessment of mammary health in transition dairy cows

Journal of Animal Science and Biotechnology, 2022
Background Mammary health is important for transition dairy cows and has been well recognized to exert decisive effects on animal welfare. However, the factors influencing mammary health are still unclear.
Luyi Jiang, Huizeng Sun, Fengfei Gu, Jin He, Fengqi Zhao, Jianxin Liu   +5 more
doaj   +1 more source

Single DNase or Proteinase Treatment Induces Change in Composition and Structural Integrity of Multispecies Oral Biofilms

Antibiotics, 2021
Biofilm virulence is mainly based on its bacterial cell surrounding biofilm matrix, which contains a scaffold of exopolysaccharides, carbohydrates, proteins, lipids, and nucleic acids.
Lamprini Karygianni, Pune N. Paqué, Thomas Attin, Thomas Thurnheer   +3 more
doaj   +1 more source

SAFETY EVALUATION OF SOME SYNTHETIC AND NATURAL PRESERVATIVES OF COSMETIC PRODUCTS [PDF]

Journal of Soil Sciences and Agricultural Engineering, 2004
The present study deals with the safety evaluation of two commonly used synthetic preservatives, i. e., germaben II (methyl-4-hydroxybenzoate) and euxyl K100 (a mixture of benzyl alcohol + methyl chloroisothiazolinone + methyl isothiazolinone) for ...
Nadia Abd- EI Moein
doaj   +1 more source

Cell-Free Double-Stranded DNA to DNase Ratio Predicts Outcome after Primary Survived Cardiac Arrest

Cells, 2022
(1) Double-stranded DNA (dsDNA) and deoxyribonuclease (DNase) as surrogate parameters for accumulating inflammatory hazards are insufficiently studied in resuscitation research. (2) Blood samples of 76 individuals after CA were analyzed 24 and 96 h after
Richard Rezar, Michael Lichtenauer, Vera Paar, Adrienne Aszlan, Thomas M. Hofbauer, Reinhard Kaufmann, Sarah Wernly, Clemens Seelmaier, Moritz Mirna, Andreas Mangold, Irene M. Lang, Uta C. Hoppe, Anna S. Ondracek, Bernhard Wernly   +13 more
doaj   +1 more source