Results 21 to 30 of about 362,662 (183)

What did CRISPR-Cas9 accomplish in its first 10 years? [PDF]

open access: yes, 2023
It’s been 10 years now from the debut of clustered regularly interspaced short palindromic repeats-associated protein 9 (CRISPR/Cas9) era in which gene engineering has never been so accessible, precise and efficient.
Khlidj, Yehya
core   +2 more sources

Autophosphorylation of type II CaM kinase in hippocampal neurons: localization of phospho- and dephosphokinase with complementary phosphorylation site-specific antibodies.

open access: yesMolecular Biology of the Cell, 1993
We have visualized the distribution of autophosphorylated type II CaM kinase in neural tissue with the use of two complementary antibodies: a monoclonal antibody that binds to the alpha and beta subunits of the kinase only when they are ...
Bruce L. Patton   +2 more
semanticscholar   +1 more source

Type of Leibniz Rule on Riemann-Liouville Variable-Order Fractional Integral and Derivative Operator [PDF]

open access: yesarXiv, 2021
In this paper, types of Leibniz Rule for Riemann-Liouville Variable-Order fractional integral and derivative Operator is developed. The product rule, quotient rule, and chain rule formulas for both integral and differential operators are established. In particular, there are four types of product rule formulas: Product rule type-I, Product rule type-II,
arxiv  

Restriction-modification system with methyl-inhibited base excision and abasic-site cleavage activities [PDF]

open access: yes, 2015
The restriction-modification systems use epigenetic modification to distinguish between self and nonself DNA. A modification enzyme transfers a methyl group to a base in a specific DNA sequence while its cognate restriction enzyme introduces breaks in ...
Fukuyo, Masaki   +9 more
core   +2 more sources

Using the EAGLE simulations to elucidate the origin of disc surface brightness profile breaks as a function of mass and environment [PDF]

open access: yes, 2021
We analyse the surface brightness profiles of disc-type galaxies in the EAGLE simulations in order to investigate the effects of galaxy mass and environment on galaxy profile types. Following observational works, we classify the simulated galaxies by their disc surface brightness profiles into single exponential (Type I), truncated (Type II) and anti ...
arxiv   +1 more source

The Potential Active Site of the Lipoprotein-specific (Type II) Signal Peptidase of Bacillus subtilis *

open access: yesJournal of Biological Chemistry, 1999
Type II signal peptidases (SPase II) remove signal peptides from lipid-modified preproteins of eubacteria. As the catalytic mechanism employed by type II SPases was not known, the present studies were aimed at the identification of their potential active
H. Tjalsma   +4 more
semanticscholar   +1 more source

Virtual Screening of Natural Products against Type II Transmembrane Serine Protease (TMPRSS2), the Priming Agent of Coronavirus 2 (SARS-CoV-2)

open access: yesMolecules, 2020
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused about 2 million infections and is responsible for more than 100,000 deaths worldwide. To date, there is no specific drug registered to combat the disease it causes, named coronavirus
Noor Rahman   +5 more
semanticscholar   +1 more source

The statistical investigation of type Ib/c and II supernovae and their host galaxies [PDF]

open access: yesAstrophysics.51:69-76,2008, 2008
This is a statistical study of the properties of type Ib/c and II supernovae and of the integral parameters of their spiral host galaxies. The methods of one-dimensional and multivariate statistics were applied to the data sample. It was found that the Ib/c supernovae are more concentrated radially toward the centers of the galaxies than those of type ...
arxiv   +1 more source

New extremal Type II $\mathbb{Z}_4$-codes of length 64 by the doubling method [PDF]

open access: yesarXiv, 2023
Extremal Type II $\mathbb{Z}_4$-codes are a class of self-dual $\mathbb{Z}_4$-codes with Euclidean weights divisible by eight and the largest possible minimum Euclidean weight for a given length. A small number of such codes is known for lengths greater than or equal to $48.$ The doubling method is a method for constructing Type II $\mathbb{Z}_4$-codes
arxiv  

The coiled coil of in vitro assembled keratin filaments is a heterodimer of type I and II keratins: use of site-specific mutagenesis and recombinant protein expression

open access: yesJournal of Cell Biology, 1990
Recombinant DNA technology has been used to analyze the first step in keratin intermediate filament (IF) assembly; i.e., the formation of the double stranded coiled coil.
M. Hatzfeld, K. Weber
semanticscholar   +1 more source

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